Yidi Zhu

Single-cell pancancer analysis reveals epithelial–immune crosstalk in shaping the premetastatic niche of liver metastasis

Hua-Kai Wang, Qiu‐Yi Tang, Zi-you Wu, Yue Yang et autres

Liver metastasis is a frequent and clinically important event across multiple solid tumors, yet a cross-cancer single-cell description of the metastatic immune ecosystem remains incomplete. Here, we integrated single-cell RNA-sequencing data from primary tumors and liver metastases across 12 cancer types and …

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Feasibility study on preparation of hydroxyapatite from calcium-containing construction waste

Yonghong Zheng, Xiufang Ou, Zhiguo Zhang, Weihua Peng et autres

In response to the environmental issues arising from the increasing volume of urban construction waste, this study utilized waste putty powder as a calcium source to synthesize hydroxyapatite (HAP) via hydrothermal synthesis. The synthesized HAP was characterized using multiple analytical techniques, including …

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Single-cell profiling unveils the immuno-favorable tumor microenvironment remodeling after successful neoadjuvant therapy for advanced gallbladder cancer

Qiu‐Yi Tang, Yi‐Jian Zhang, Zi-you Wu, Tianyu Zhang et autres

BACKGROUND: Neoadjuvant treatment has demonstrated clinical benefits in advanced gallbladder cancer (GBC). However, the overall response rate remains suboptimal, and the underlying mechanisms driving treatment efficacy are not fully understood. MATERIALS AND METHODS: This study aimed to evaluate the therapeutic effects of …

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Cerebrovascular Reactivity Modulates Spontaneous Brain Activity Abnormalities in Alzheimer's disease: A Resting-State Functional MRI Study

Tang Xue, Luoyu Wang, Qi Feng, Qingqing Wen et autres

Motivation: In Alzheimer's disease (AD), the effect of vascular factors on the BOLD signal needs further study. Goal(s): To investigate the alterations of the dynamic amplitude of low-frequency fluctuation (dALFF) following the adjustment of cerebrovascular reactivity (CVR) factors in AD patients. Approach: …

Differential Cerebrovascular Reactivity in the Precuneus: A Resting-State fMRI Study of Alzheimer's Disease and Mild Cognitive Impairment

Luoyu Wang, Qi Feng, Hanjun Hu, Qingqing Wen et autres

Motivation: The individual cerebral hemodynamics variations and their relationships with cognitive function are not fully understood for Alzheimer's disease (AD) spectrum disorders. Goal(s): To investigate changes in cerebrovascular reactivity (CVR) obtained by resting-state functional MRI (rs-fMRI) in patients with mild cognitive impairment …

An end-to-end interpretable machine-learning-based framework for early-stage diagnosis of gallbladder cancer using multi-modality medical data

Chuang Miao, Yidi Zhu, Yijun Shu, Xiangsong Wu et autres

BACKGROUND: The accurate early-stage diagnosis of gallbladder cancer (GBC) is regarded as one of the major challenges in the field of oncology. However, few studies have focused on the comprehensive classification of GBC based on multiple modalities. This study aims to develop …

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Ecological Risk Assessment of Heavy Metal Occurrences in the Coal-Fired Furnace Bottom Slags of Power Plants

Zhiguo Zhang, Qingbin Ma, Yonghong Zheng, Yidi Zhu et autres

This study explored the ecological risks related to bulk resource utilization of industrial solid waste slag from the Yuanyanghu Power Plant in the Ningdong Energy and Chemical Industry Base. Scanning electron microscopy, energy spectrum analysis, and X-ray diffraction were used to characterize …

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Cerebral Perfusion Features in Takayasu Arteritis: Insights From pCASL MRI

Yi Zhao, Hongtao Zhang, Fang Kong, Li Su et autres

OBJECTIVE: This study aimed to investigate the cerebral perfusion features in patients with Takayasu arteritis (TA) involving the brain blood supply arteries with pseudo-continuous arterial spin labeling magnetic resonance (pCASL) imaging. METHODS: pCASL-MRI was utilized to measure the cerebral perfusion in the …

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Resting-state functional magnetic resonance imaging study on cerebrovascular reactivity changes in the precuneus of Alzheimer’s disease and mild cognitive impairment patients

Xue Tang, Luoyu Wang, Qi Feng, Hanjun Hu et autres

Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by memory impairment and cognitive decline, ultimately culminating in dementia. This study aims to evaluate cerebrovascular reactivity (CVR) and functional connectivity (FC) in patients with AD and mild cognitive impairment (MCI) using resting-state …

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PTBP3 Mediates IL‐18 Exon Skipping to Promote Immune Escape in Gallbladder Cancer

Cheng Zhao, Yuhan Zhang, Yidi Zhu, Ziyi Yang et autres

Gallbladder cancer (GBC) is the most common malignant tumor of the biliary system, with poor response to current treatments. Abnormal alternative splicing has been associated with the development of a variety of tumors. Combining the GEO database and GBC mRNA-seq analysis, it …

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Sonar Waveform Synthesis Based on Mel Generative Adversarial Networks with Self-Attention Mechanisms

Yidi Zhu, Zhiquan Bai, Xiuwen Li, Hai‐Xiao Wang et autres

Considering the complicated process of traditional sonar waveform synthesis method, in this study, we apply models from the speech domain to the underwater acoustic domain based on deep learning algorithms using a transfer learning approach. The core of this study lies in …

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Underwater Acoustic Signal Recognition with Small Transfer Learning-based Training Samples

Zhiquan Bai, Yidi Zhu, Xuanlin Li, Hai‐Xiao Wang et autres

To address the challenges of underwater acoustic signal recognition under small sample training conditions, we propose a deep learning model based on transfer learning. The proposed model integrates a pretrained VGGish system with bidirectional long short-term memory (BiLSTM) to achieve high-performance recognition …

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