Accès ouvert
2025
article
OpenAlex
Daniel J. Scheese, Peng Lü, Hannah Moore, Koichi Tsuboi et autres
BACKGROUND AND AIMS: Necrotizing enterocolitis (NEC) is a life-threatening condition in premature infants, marked by acute intestinal necrosis. NEC develops in part after activation of the lipopolysaccharide receptor toll-like receptor 4 (TLR4) by intestinal microbes in the intestinal epithelium. Previous authors have …
us
(code pays fourni par la source)
Accès ouvert
2024
article
OpenAlex
Zachariah Raouf, Steve N. Steinway, Daniel J. Scheese, Carla Marisa Lopez et autres
BACKGROUND & AIMS: The abdominal discomfort experienced by patients with colitis may be attributable in part to the presence of small intestinal dysmotility, yet mechanisms linking colonic inflammation with small-bowel motility remain largely unexplored. We hypothesize that colitis results in small intestinal …
us
(code pays fourni par la source)
Accès ouvert
2023
article
OpenAlex
Chhinder Pal Sodhi, Raheel Ahmad, William B. Fulton, Carla Marisa Lopez et autres
This study reveals that the administration of human milk oligosaccharides, which are present in human breast milk, can interfere with the proinflammatory gut-brain axis and prevent neuroinflammation in the setting of necrotizing enterocolitis, a major intestinal disorder seen in premature infants.
us
(code pays fourni par la source)