Mark Reimers

SpatiaXen: an interactive platform for cell-type-resolved spatial transcriptomics analysis of Xenium data

Anirban Chakraborty, Cort Thompson, Lauren Wade-Kleyn, Mark Reimers et autres

Title: SpatiaXen: An Open-Source Interactive Platform for Cell-Type-Resolved Spatial Transcriptomics Analysis. Background: In-situ spatial transcriptomics technologies, such as the 10x Genomics Xenium platform, enable single-cell-resolution analysis of gene expression while also preserving the spatial organization of tissue. These platforms can provide new …

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SpatiaXen: an interactive platform for cell-type-resolved spatial transcriptomics analysis of Xenium data

Anirban Chakraborty, Cort Thompson, Lauren Wade-Kleyn, Mark Reimers et autres

Title: SpatiaXen: An Open-Source Interactive Platform for Cell-Type-Resolved Spatial Transcriptomics Analysis. Background: In-situ spatial transcriptomics technologies, such as the 10x Genomics Xenium platform, enable single-cell-resolution analysis of gene expression while also preserving the spatial organization of tissue. These platforms can provide new …

us (code pays fourni par la source)

Human resilience depends on distinctively human brain circuitry and development

Mark Reimers

Most studies of psychological resilience in the past century have focused on either biological or social psychological correlates of resilience or depression. This article argues that the two approaches need to be integrated because of uniquely human processes of cortical development during …

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Safety considerations for dietary supplement manufacturers in the United States

Jay E. Sirois, S A G Reddy, Tony T. Nguyen, Heather J. Walker et autres

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HPV+ head and neck cancer–derived small extracellular vesicles communicate with TRPV1+ neurons to mediate cancer pain

Kufreobong E. Inyang, Christine M. Evans, Matthew Heussner, Margaret G. Petroff et autres

ABSTRACT: Severe pain is often experienced by patients with head and neck cancer and is associated with a poor prognosis. Despite its frequency and severity, current treatments fail to adequately control cancer-associated pain because of our lack of mechanistic understanding. Although recent …

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Author Correction: Sparse whole-genome sequencing identifies two loci for major depressive disorder

Na Cai, Tim B. Bigdeli, Warren W. Kretzschmar, Yihan Li et autres

gb, us, cn, jp, de, mo, dk, sa (code pays fourni par la source)

Supplementary Data from MicroRNA Expression in Squamous Cell Carcinoma and Adenocarcinoma of the Esophagus: Associations with Survival

Ewy A. Mathé, Giang Huong Nguyen, Elise D. Bowman, Yiqiang Zhao et autres

Supplementary Data from MicroRNA Expression in Squamous Cell Carcinoma and Adenocarcinoma of the Esophagus: Associations with Survival

Supplementary Material from In vitro differential sensitivity of melanomas to phenothiazines is based on the presence of codon 600 BRAF mutation

Ogechi N. Ikediobi, Mark Reimers, Steffen Durinck, Paul E. Blower et autres

Supplementary Material from In vitro differential sensitivity of melanomas to phenothiazines is based on the presence of codon 600 BRAF mutation

Data from MicroRNA Expression in Squamous Cell Carcinoma and Adenocarcinoma of the Esophagus: Associations with Survival

Ewy A. Mathé, Giang Huong Nguyen, Elise D. Bowman, Yiqiang Zhao et autres

Abstract Purpose: The dismal outcome of esophageal cancer patients highlights the need for novel prognostic biomarkers, such as microRNAs (miRNA). Although recent studies have established the role of miRNAs in esophageal carcinoma, a comprehensive multicenter study investigating different histologic types, including squamous …

Data from In vitro differential sensitivity of melanomas to phenothiazines is based on the presence of codon 600 BRAF mutation

Ogechi N. Ikediobi, Mark Reimers, Steffen Durinck, Paul E. Blower et autres

Abstract The panel of 60 human cancer cell lines (the NCI-60) assembled by the National Cancer Institute for anticancer drug discovery is a widely used resource. We previously sequenced 24 cancer genes in those cell lines. Eleven of the genes were found …

us, gb, cn (code pays fourni par la source)

Data from MicroRNA Expression in Squamous Cell Carcinoma and Adenocarcinoma of the Esophagus: Associations with Survival

Ewy A. Mathé, Giang Huong Nguyen, Elise D. Bowman, Yiqiang Zhao et autres

Abstract Purpose: The dismal outcome of esophageal cancer patients highlights the need for novel prognostic biomarkers, such as microRNAs (miRNA). Although recent studies have established the role of miRNAs in esophageal carcinoma, a comprehensive multicenter study investigating different histologic types, including squamous …

Data from In vitro differential sensitivity of melanomas to phenothiazines is based on the presence of codon 600 BRAF mutation

Ogechi N. Ikediobi, Mark Reimers, Steffen Durinck, Paul E. Blower et autres

Abstract The panel of 60 human cancer cell lines (the NCI-60) assembled by the National Cancer Institute for anticancer drug discovery is a widely used resource. We previously sequenced 24 cancer genes in those cell lines. Eleven of the genes were found …