A. P. Marsh

Validating an open access and low-cost 3D-printed dermatoscope for enhanced accessibility into dermoscopy

Amy Prideaux, Jack Norris, Hagar Elgezeri, Kalina Bridgewater et autres

Traditional dermatoscopes remain expensive and therefore relatively inaccessible, particularly in the resource-poor and nonspecialist setting. To address this concern, we have developed a self-assembly three-dimensional (3D)-printed dermatoscope, which has an estimated total cost of £5–20. No significant difference between traditional and 3D-printed …

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Development of Subject-Specific Proximal Femur Finite Element Models Of Older Adults with Obesity to Evaluate the Effects of Weight Loss on Bone Strength

Samantha L. Schoell, Anne Weaver, Daniel P. Beavers, Leon Lenchik et autres

STUDY BACKGROUND: Recommendation of intentional weight loss in older adults remains controversial, due in part to the loss of bone mineral density (BMD) known to accompany weight loss. While finite element (FE) models have been used to assess bone strength, these methods …

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SELF-REPORTED PHYSICAL FUNCTION AS A PREDICTOR OF HOSPITALIZATION IN THE LIFE STUDY

Kathryn E. Callahan, Laura Lovato, Marilyn E. Miller, A. P. Marsh et autres

Background: For older adults, hospitalization confers functional loss, which in turn increases hospitalizations. Physical function screening may identify an at-risk population for early intervention. The Mobility Assessment Tool – short form (MAT-sf) is a brief, innovative, avatar-based self-report tool that predicts mobility …

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ANIMATED VIDEO TECHNOLOGY: ADVANCING THE ASSESSMENT OF MOBILITY

W. Jack Rejeski, A. P. Marsh, Ross Barnard, Jason Fanning et autres

Within the past 10 years, our research group has used Animated Video Technology as a means of enriching assessment stimuli when evaluating various aspects of physical function. This session focuses on the mobility assessment tool-short form (MAT-sf) and also briefly illustrates how …

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Legacy effects of short-term intentional weight loss on total body and thigh composition in overweight and obese older adults

Elizabeth A. Chmelo, Daniel P. Beavers, Mary F. Lyles, A. P. Marsh et autres

OBJECTIVE: Weight regain following intentional weight loss may negatively impact body composition, accelerating fat regain and increasing risk of physical disability. The purpose of this study was to compare long-term changes in whole body and thigh composition in obese older adults who …

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Human Slow Troponin T (TNNT1) Pre-mRNA Alternative Splicing Is an Indicator of Skeletal Muscle Response to Resistance Exercise in Older Adults

Tan Zhang, Seung-Jun Choi, Zhou Wang, Alexander Birbrair et autres

Slow skeletal muscle troponin T (TNNT1) pre-messenger RNA alternative splicing (AS) provides transcript diversity and increases the variety of proteins the gene encodes. Here, we identified three major TNNT1 splicing patterns (AS1-3), quantified their expression in the vastus lateralis muscle of older …

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The MAT-sf: Clinical Relevance and Validity

W. Jack Rejeski, A. P. Marsh, Steve Anton, S.-H. Chen et autres

BACKGROUND: The measurement of mobility is essential to both aging research and clinical practice. A newly developed self-report measure of mobility, the mobility assessment tool-short form (MAT-sf), uses video animations to improve measurement accuracy/precision. Using a large baseline data set, we recalibrated …

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Resistance Training and Pioglitazone Lead to Improvements in Muscle Power During Voluntary Weight Loss in Older Adults

A. P. Marsh, M. Kyla Shea, R. M. Vance Locke, Michael E. Miller et autres

BACKGROUND: The prevalence of obesity in older adults is increasing but concerns exist about the effect of weight loss on muscle function. Demonstrating that muscle strength and power are not adversely affected during "intentional" weight loss in older adults is important given …

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Physical Activity Increases Gains in and Prevents Loss of Physical Function: Results From the Lifestyle Interventions and Independence for Elders Pilot Study

Edward H. Ip, Timothy S. Church, Sarah A. Marshall, Qi Zhang et autres

BACKGROUND: Physical activity (PA) appears to have a positive effect on physical function, however, studies have not examined multiple indices of physical function jointly nor have they conceptualized physical functioning as a state rather than a trait. METHODS: About 424 men and …

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LATISSIMUS DORSI TENDON TRANSFER FOR IRREPARABLE ROTATOR CUFF TEARS

A. P. Marsh, Umberto G. Fazzi

Massive, irreparable rotator cuff tears occur in about 15% of patients with ruptures of the rotator cuff tendons. There is no consistently agreed management for irreparable rotator cuff tears, however, latissimus dorsi tendon transfer is a recognised technique. We aimed to review …

Muscle Strength and BMI as Predictors of Major Mobility Disability in the Lifestyle Interventions and Independence for Elders Pilot (LIFE-P)

A. P. Marsh, W. Jack Rejeski, Mark A. Espeland, Michael E. Miller et autres

BACKGROUND: Muscle weakness and obesity are two significant threats to mobility facing the increasing number of older adults. To date, there are no studies that have examined the association of strength and body mass index (BMI) on event rates on a widely …

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Change in 25-Hydroxyvitamin D and Physical Performance in Older Adults

Denise K. Houston, Janet A. Tooze, Dorothy B. Hausman, Mary Ann Johnson et autres

BACKGROUND: Vitamin D deficiency is common among older adults and is associated with poor physical performance; however, studies examining longitudinal changes in 25-hydroxyvitamin D (25[OH]D) and physical performance are lacking. We examined the association between 25(OH)D and physical performance over 12 months …

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