A‐L Hartikainen

Physical health of singleton children born after frozen embryo transfer using slow freezing: a 3-year follow-up study

Sari Pelkonen, Mika Gissler, Sari Koivurova, Satu S. Lehtinen et autres

STUDY QUESTION: Are there differences in the physical health of singleton children born after frozen embryo transfer (FET) compared with children born after fresh embryo transfer (fresh ET)? SUMMARY ANSWER: Register-based health indicators were similar among FET and fresh ET singletons during …

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Major congenital anomalies in children born after frozen embryo transfer: a cohort study 1995-2006

Sari Pelkonen, A‐L Hartikainen, Annukka Ritvanen, Riku-Jaakko Koivunen et autres

STUDY QUESTION: Is there a different risk for major congenital anomalies (CAs) in children born after frozen-thawed embryo transfer (FET) compared with children born after fresh embryo transfer (ET)? SUMMARY ANSWER: Children born after FET have a similar risk of developing major …

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Menstrual disorders in adolescence: a marker for hyperandrogenaemia and increased metabolic risks in later life? Finnish general population-based birth cohort study

Pekka Pinola, Hany Lashen, Aini H. Bloigu, Katri S. Puukka et autres

STUDY QUESTION: Are self-reported menstrual disorders associated with hyperandrogenaemia and metabolic disturbances as early as in adolescence? SUMMARY ANSWER: Menstrual disorders at the age 16 are a good marker of hyperandrogenaemia, and an adverse lipid profile was associated with higher androgen levels. …

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Maternal weight gain during the first half of pregnancy and offspring obesity at 16 years: a prospective cohort study

Jaana H. Laitinen, Anne Jääskeläinen, A‐L Hartikainen, Ulla Sovio et autres

OBJECTIVE: To assess the association between maternal gestational weight gain (GWG) during the first 20 weeks of gestation and overweight/obesity and abdominal obesity of offspring at the age of 16 years. DESIGN: A prospective cohort study. SETTING: The two northernmost provinces of …

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Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk.

International Consortium for Blood Pressure Genome-Wide Associat, GB Ehret, PB Munroe, K M Rice et autres

Blood pressure is a heritable trait influenced by several biological pathways and responsive to environmental stimuli. Over one billion people worldwide have hypertension (≥140 mm Hg systolic blood pressure or ≥90 mm Hg diastolic blood pressure). Even small increments in blood pressure …

Smoking habits and early pregnancy thyroid hormone and antibody levels

Tuija I. Männistö, Aimo Ruokonen, H-M Surcel, Aini H. Bloigu et autres

Relation of Immediate Postnatal Growth With Obesity and Related Metabolic Risk Factors in Adulthood

Ioanna Tzoulaki, Ulla Sovio, Demetris Pillas, A‐L Hartikainen et autres

New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk (vol 42, pg 105, 2010)

Josée Dupuis, Claudia Langenberg, Inga Prokopenko, Rita Saxena et autres

Perinatal outcome of children born after frozen and fresh embryo transfer: the Finnish cohort study 1995–2006

Sari Pelkonen, Riku-Jaakko Koivunen, Mika Gissler, S. Nuojua-Huttunen et autres

BACKGROUND: The number of children born after frozen embryo transfer (FET) is steadily rising. However, studies on obstetric and perinatal outcomes are limited. Our primary aim was to compare the perinatal health of children born after FET and fresh embryo transfer, and …

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Treating Miscarriages: A Randomized Study of Cost-Effectiveness in Medical or Surgical Choice

Maarit J. Niinimäki, Petri J. Karinen, A‐L Hartikainen, Anneli M. Pouta

Miscarriage occurs in up to 15% of women with a history of at least 1 miscarriage during their reproductive life span. A meta-analysis reported that treatment of miscarriage surgically was considerably more effective than medical or expectant management when complete abortion was …

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Treating miscarriages: a randomised study of cost‐effectiveness in medical or surgical choice

Maarit J. Niinimäki, Petri J. Karinen, A‐L Hartikainen, Anneli M. Pouta

OBJECTIVE: The aim was to carry out a cost effectiveness analysis (CEA) of medical and surgical treatment of miscarriage using quantitative and qualitative indicators. DESIGN: A prospective study where the data of the clinical course of the treatment and the patients; experiences …

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Common genetic variation near MC4R is associated with eating behaviour patterns in European populations

Fanny Stutzmann, Stéphane Cauchi, Emmanuelle Durand, C. Calvacanti-Proença et autres

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