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Profil bibliographique

Hubert Laude

Informations fournies par OpenAlex. Research Africa ne déduit ni nationalité, ni poste, ni coordonnées personnelles.

109Publications signalées
3959Citations signalées
1Affiliations récentes

Les institutions déclarées

Les domaines associés

Prion Diseases and Protein MisfoldingAnimal Virus Infections StudiesViral gastroenteritis research and epidemiologyNeurological diseases and metabolismVirus-based gene therapy research

Les publications récentes

Accès ouvert 2015 article OpenAlex

Prion protein localizes at the ciliary base during neural and cardiovascular development and its depletion affects α-tubulin post-translational modifications

Sophie Halliez, Severine Martin‐Lannerée, Bruno Passet, Julia Hernandez-Rapp et autres

Although conversion of the cellular form of the prion protein (PrP(C)) into a misfolded isoform is the underlying cause of prion diseases, understanding PrP(C) physiological functions has remained challenging. PrP(C) depletion or overexpression alters the proliferation and differentiation properties of various types …

fr (code pays fourni par la source)

14 citations Scientific Reports
Accès ouvert 2014 article OpenAlex

To develop with or without the prion protein

Sophie Halliez, Bruno Passet, Séverine Martin-Lannerée, Julia Hernandez-Rapp et autres

The deletion of the cellular form of the prion protein (PrP(C)) in mouse, goat, and cattle has no drastic phenotypic consequence. This stands in apparent contradiction with PrP(C) quasi-ubiquitous expression and conserved primary and tertiary structures in mammals, and its pivotal role …

fr (code pays fourni par la source)

21 citations Frontiers in Cell and Developmental Biology
Accès ouvert 2014 article OpenAlex

The prion protein family: a view from the placenta

Samira Makzhami, Bruno Passet, Sophie Halliez, Johan Castille et autres

Based on its developmental pattern of expression, early studies suggested the implication of the mammalian Prion protein PrP, a glycosylphosphatidylinositol-anchored ubiquitously expressed and evolutionary conserved glycoprotein encoded by the Prnp gene, in early embryogenesis. However, gene invalidation in several species did not …

Maroc, fr (code pays fourni par la source)

16 citations Frontiers in Cell and Developmental Biology
Accès ouvert 2013 erratum OpenAlex

Correction: Glycoform-Selective Prion Formation in Sporadic and Familial Forms of Prion Disease

Xiangzhu Xiao, Jue Yuan, Stéphane Haà ̄k, Ignazio Calì et autres

The four glycoforms of the cellular prion protein (PrP C ) variably glycosylated at the two N-linked glycosylation sites are converted into their pathological forms (PrP Sc ) in most cases of sporadic prion diseases.However, a prominent molecular characteristic of PrP Sc …

us, cn, fr, Maroc, nl, jp (code pays fourni par la source)

19 citations PLoS ONE
Accès ouvert 2011 article OpenAlex

Atypical Scrapie Isolates Involve a Uniform Prion Species with a Complex Molecular Signature

Dorothea R. Götte, Sylvie Lafond Benestad, Hubert Laude, Andreas Zurbriggen et autres

The pathobiology of atypical scrapie, a prion disease affecting sheep and goats, is still poorly understood. In a previous study, we demonstrated that atypical scrapie affecting small ruminants in Switzerland differs in the neuroanatomical distribution of the pathological prion protein (PrP(d)). To …

ch, no, fr (code pays fourni par la source)

24 citations PLoS ONE

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