Yasuo Totsuka

Impaired Awareness of Hypoglycemia and Driving Mishaps in Patients with Type 1 Diabetes Mellitus: A Multi-center Survey in Japan

Naoki Sakane, Kazuhiko Kotani, Kokoro Tsuzaki, Masami Nishi et autres

Naoki Sakane1*, Kazuhiko Kotani1,2, Kokoro Tsuzaki1, Masami Nishi1,20, Kaoru Takahashi1,3, Takashi Murata4, Kazunori Yamada4, Kentaro Okazaki5, Katsuyuki Yanagisawa6, Kenichi Yamada7, Nobuichi Kuribayashi8, Yasuo Totsuka9, Toru Hiyoshi10, Motoji Naka11, Masatake Sugimoto12, Yuji Aoki13, Masako Waki14, Miyuki Furuya15, Haruko Kitaoka16, Mariko Oishi17, Ikki Shimizu18, …

Fear of hypoglycemia and its determinants in insulin‐treated patients with type 2 diabetes mellitus

Naoki Sakane, Kazuhiko Kotani, Kokoro Tsuzaki, Masami Nishi et autres

The aim of the present study was to investigate the prevalence of fear of hypoglycemia, in association with severe hypoglycemia and social factors, in insulin-treated patients with type 2 diabetes mellitus. A questionnaire survey on hypoglycemia and patient-physician communication was carried out …

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Glucagon Underutilized Among Type 1 Diabetes Mellitus Patients in Japan

Takashi Murata, KENTARO OKAZAKI, Katsuyuki Yanagisawa, Kenichi Yamada et autres

AIM: Glucagon is recommended to treat severe hypoglycemia in nonhospital environments, when a patient with type 1 diabetes mellitus (T1DM) is unconscious and unable to eat or drink. However, the actual possession rate of glucagon in Japan has not been investigated. SUBJECTS …

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[Medical nutrition therapy and exercise in type 1 diabetes].

Yasuo Totsuka

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[Glucagonoma and glucose intolerance].

Miho Ajima, Yasuo Totsuka

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[Somatostatinoma and glucose intolerance].

Kunichi Kouyama, Yasuo Totsuka

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Blood Sugar Control Reverses the Increase in Urinary Excretion of Prostaglandin D Synthase in Diabetic Patients

Kumiko Hamano, Yasuo Totsuka, Miho Ajima, Tomoko Gomi et autres

BACKGROUND/AIMS: We investigated basal levels of serum and urinary lipocalin-type prostaglandin D synthase/beta-trace (L-PGDS) in type-2 diabetic patients and explored whether glycemic control affects L-PGDS status in another 55 diabetic inpatients with normoalbuminuria. METHODS: Fifty-five type-2 diabetic outpatients (HbA1c, 9.14 +/- 0.20%; …

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Urinary Prostaglandin D Synthase (β-Trace) Excretion Increases in the Early Stage of Diabetes mellitus

Nobuhito Hirawa, Yoshio Uehara, Toshio Ikeda, Tomoko Gomi et autres

OBJECTIVE: Circulating levels of lipocalin-type prostaglandin D synthase (L-PGDS)/beta-trace reportedly increase in renal failure as well as in cardiovascular injuries. We investigated the alterations of L-PGDS in urine and plasma in the early stage of type-2 diabetic patients. METHOD: Thirty-six type-2 diabetic …

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Ectopic Adrenocorticotropin Syndrome Exhibiting Paradoxical Adrenocorticotropin Responsiveness to Gonadotropin-Releasing Hormone.

Makoto Ujihara, Takanobu Yoshimoto, REIKA CHO, Yasuo Totsuka et autres

In a 37-year-old man who had Cushing's syndrome, investigations, including overnight dexamethasone suppression test, corticotropin-releasing hormone (CRH) test, pituitary MRI and inferior petrosal sinus sampling suggested the presence of ectopic adrenocorticotropin (ACTH) production. Interestingly, gonadotropin-releasing hormone (GnRH) increased plasma ACTH from 73 …

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Subject Index Vol. 87, 2001

Yasuo Totsuka, Claudio Angelini, Salvatore Badalamenti, Masako Ohnishi et autres

A Novel Activating Mutation in Calcium-Sensing Receptor Gene Associated with a Family of Autosomal Dominant Hypocalcemia1

Ryo Okazaki, Noriko Chikatsu, Masami Nakatsu, Yasuhiro Takeuchi et autres

Autosomal dominant hypocalcemia (ADH), caused by activating mutations of the calcium-sensing receptor (CaSR), is characterized by hypocalcemia with an inappropriately low concentration of PTH. Among 11 missense mutations of CaSR reported to date in patients with ADH or sporadic hypocalcemia, functional properties …

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Serum leptin levels during cancer chemotherapy

Kensuke Usuki, Ryuji Okazaki, Seiko Iki, Mizuho MURAMATSU et autres

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