Colin N. FERGUSON

Exploring Unmet Needs and Interventions to Improve Frailty in Adults With Heart Failure: A Focus Group Study

J. E. R. McDonagh, Henok Mulugeta, Scott William, Colin N. FERGUSON

au (code pays fourni par la source)

ESCAPE-CS-Explore: Barriers and Enablers to Quality Cardiogenic Shock Care: A Focus Group Study

S William, Sabine M. Allida, Mark Dennis, Pankaj Jain et autres

au (code pays fourni par la source)

HYPERLUCENCY ON CHEST RADIOGRAPHS

Harith Altemimi, V. P. Jadhav, Lorraine Apps, Nigel Hollister et autres

Liver albumin synthesis in sepsis in the rat: influence of parenteral nutrition, glutamine and growth hormone

Michael J. O’Leary, Michael Koll, Colin N. FERGUSON, J. H. Coakley et autres

The effect of sepsis on liver synthesis of albumin remains controversial, with studies in man suggesting that synthesis increases, whereas in animals increased, decreased and unaltered synthesis have been reported. To reconcile these conflicting data, total and relative albumin synthesis was measured …

au, gb, us (code pays fourni par la source)

Influence Of Starvation, Surgery, and Sepsis on Cardiac Protein Synthesis in Rats: Effects of Parenteral Nutrition, Glutamine, and Growth Hormone

Michael J. O’Leary, Colin N. FERGUSON, J. H. Coakley, Charles Hinds et autres

The effect of sepsis on the rate of protein synthesis in the heart is poorly described. We have investigated changes in protein synthesis in the ventricles of the heart over time after cecal ligation and puncture (CLP) in rats in comparison with …

au, gb (code pays fourni par la source)

Effect of growth hormone on muscle and liver protein synthesis in septic rats receiving glutamine-enriched parenteral nutrition

Michael J. O’Leary, Colin N. FERGUSON, Michael J. Rennie, Charles Hinds et autres

OBJECTIVE: Administration of recombinant human growth hormone (rhGH) to critically ill adults in an attempt to attenuate catabolism was associated with increased morbidity and mortality. Possible explanations included inhibition of glutamine release from skeletal muscle and consequent restriction of splanchnic glutamine supply. …

gb (code pays fourni par la source)

Sequential changes in in vivo muscle and liver protein synthesis and plasma and tissue glutamine levels in sepsis in the rat

Michael J. O’Leary, Colin N. FERGUSON, Michael J. Rennie, Charles Hinds et autres

We have investigated sequential changes in skeletal muscle and hepatic protein synthesis following sepsis, and their relationship to changes in circulating and tissue glutamine concentrations. Male Wistar rats underwent caecal ligation and puncture (CLP) or sham operation, with starvation, and were killed …

gb (code pays fourni par la source)

Sequential changes in in vivo muscle and liver protein synthesis and plasma and tissue glutamine levels in sepsis in the rat

Michael J. O’Leary, Colin N. FERGUSON, Michael J. Rennie, Charles Hinds et autres

We have investigated sequential changes in skeletal muscle and hepatic protein synthesis following sepsis, and their relationship to changes in circulating and tissue glutamine concentrations. Male Wistar rats underwent caecal ligation and puncture (CLP) or sham operation, with starvation, and were killed …

gb (code pays fourni par la source)

In rats with sepsis, the acute fall in IGF-I is associated with an increase in circulating growth hormone-binding protein levels

Michael J. O’Leary, Naomi D. Quinton, Colin N. FERGUSON, Victor R. Preedy et autres

gb, au (code pays fourni par la source)

Oxygenator exhaust capnography as an index of arterial carbon dioxide tension during cardiopulmonary bypass using a membrane oxygenator

M J O’Leary, S. P. J. MACDONNELL, Colin N. FERGUSON

gb (code pays fourni par la source)

DESENSITIZATION OF THE INFLAMMATORY RESPONSE IN HUMANS

Tony Ng, Fiona A. M. Gibson, Keith E. Nye, Philip Hughes et autres

Although circulating levels of interleukin 8 (IL-8), a potent pro-inflammatory chemokine, and many other inflammatory mediators increase in response to cardiopulmonary bypass, only a small proportion of patients develop a clinically significant systemic inflammatory response. The natural mechanisms that control the inflammatory …

gb (code pays fourni par la source)

Reduction in circulating IGF-I and hepatic IGF-I mRNA levels after caecal ligation and puncture are associated with differential regulation of hepatic IGF-binding protein-1, -2 and -3 mRNA levels

Javier Rodriguez-Arnao, G. D. Yarwood, Colin N. FERGUSON, JOHN P. MIELL et autres

Sepsis is characterized by a severe shift in metabolism, characterized by low IGF-I levels. We have studied the influence of caecal ligation and puncture (CLP) on the levels of circulating IGF-I and hepatic IGF-I and IGF-binding protein (IGFBP)-1, -2 and -3 mRNA …

gb (code pays fourni par la source)