M. Vautier

Generation of a human induced pluripotent stem cell line (FLENIi004-A) from an Autosomal-Dominant Alzheimer’s disease PSEN1 p.M146L patient

M. Vautier, Patricio Chrem Méndez, Guillermo Jerez Ferreyra, Victoria Massazza et autres

Human induced pluripotent stem cell (hiPSC) line FLENIi004-A was generated from peripheral blood mononuclear cells (PBMCs) using the lentiviral-hSTEMCCA-loxP vector. FLENIi004-A was derived from a 41-year-old Argentinean Caucasian male patient with Autosomal-Dominant Alzheimer's Disease, who carried the heterozygous PSEN1 p.M146L mutation. The …

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“Identification of microRNAs regulated by E2F transcription factors in human pluripotent stem cells”

María Soledad Rodríguez-Varela, M. Vautier, Sofía Mucci, Luciana Isaja et autres

ABSTRACT Human pluripotent stem cells (hPSCs), which include embryonic and induced pluripotent stem cells (hESCs and hiPSCs, respectively), have an unusual cell cycle structure which consists of a short G1 phase and the absence of the G1/S checkpoint regulation. E2F transcription factors …

ar (code pays fourni par la source)

Voie de signalisation JAK/STAT dans la maladie de Takayasu

P. Regner, L Alexandre, Mancuso Anna, A.C. Desbois et autres

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272 8-(1-Anilino)ethyl)-2-morpholino-4-oxo-4H-chromene-6-carboxamides as PI3Kbeta/delta inhibitors: structure–activity relationships and identification of AZD8186, a clinical candidate for the treatment of PTEN deficient tumours

Bernard Barlaam, Sabina Cosulich, Sébastien L. Degorce, Martina Fitzek et autres