Accès ouvert
2026
article
OpenAlex
Antonia Dalmer, Stefan Siewert, Dominique Passler, Hagen Paetow et autres
PURPOSE: A standardized, population-based three-dimensional (3D) computer-aided design (CAD) model of the intracranial arterial system was developed from time-of-flight magnetic resonance angiography (TOF-MRA) data of the Study of Health in Pomerania (SHIP) cohort, tailored for realistic simulation and experimental neurovascular applications. METHODS: …
de
(code pays fourni par la source)
Accès ouvert
2025
article
OpenAlex
Michael Stiehm, Christoph Brandt-Wunderlich, Arne Briest, Leonard Pitts et autres
Abstract Acute type A aortic dissection (ATAAD) remains a life-threatening condition with high morbidity and mortality rates despite advancements in surgical and perioperative management. The Ascyrus Medical Dissection Stent (AMDS) has been introduced as an adjunct to the hemiarch procedure to reduce …
de
(code pays fourni par la source)
Accès ouvert
2025
article
OpenAlex
Jan Oldenburg, Finja Borowski, Laura Supp, Matthias Leuchter et autres
Abstract Minimally invasive transcatheter aortic valve replacement (TAVR) has become the preferred procedure for patients with aortic valve stenosis or insufficiency who are at high risk for conventional open-heart surgery. The favorable clinical outcomes observed in high-risk patients have led to an …
de
(code pays fourni par la source)
Accès ouvert
2025
article
OpenAlex
W. J. Schmidt, Swen Großmann, Eric Bohne, Peter Behrens et autres
Abstract Radiopacity is an important prerequisite for X-ray visibility of implants. Existing standards refer to the use of Xray systems for medical imaging. Micro Computed Tomography (μCT) technology is available with high resolution imaging. Experimental studies should verify the comparability of radiopacity …
de
(code pays fourni par la source)
Accès ouvert
2025
article
OpenAlex
Vivien Kauschke, Sylvia Pfensig, Valeria Khaimov, Ariane Dierke et autres
Abstract In upper limb amputees implantation of prostheses equipped with electrodes to innervate respective musculature might improve sensitivity and life quality. Besides different types of prostheses being available, there is still a need for devices that provide more comfort and functionality to …
de
(code pays fourni par la source)
Accès ouvert
2025
article
OpenAlex
Swen Großmann, Rosa Maria Staufer, Niels Grabow, Valeria Khaimov et autres
Abstract Stents play a vital role in the treatment of cardiovascular diseases. In this context, endothelialization is of crucial importance for the final implant performance and the key to an effective treatment. To enhance endothelial cell (EC) attachment and surface coverage, laser-induced …
de
(code pays fourni par la source)
Accès ouvert
2025
article
OpenAlex
Matthias Leuchter, Laura Supp, Jan Oldenburg, Michael Stiehm et autres
Abstract The assesment of the safety and efficacy of medical devices can be time-consuming, expensive, and raise ethical concerns. Additionally, the high costs of innovation and lengthy development times may result in increased prices and unequal access for certain patient groups. In …
de
(code pays fourni par la source)
Accès ouvert
2025
article
OpenAlex
Klaus‐Peter Schmitz, Tanner L. Larson, Michael W. Borovich, Xianfang Wu et autres
Peripheral nerve injuries (PNIs) have a significant impact on the quality of life for patients suffering from trauma or disease. In injuries with critical nerve gaps, PN regeneration requires tissue scaffolds with appropriate physiological properties that promote cell growth and functions. Hydrogel …
us, se, fr
(code pays fourni par la source)
Accès ouvert
2025
article
OpenAlex
Laura Supp, Jan Oldenburg, Matthias Leuchter, Jan Brüning et autres
Transcatheter aortic valve replacement (TAVR) has revolutionized the treatment of severe aortic stenosis, yet paravalvular leakage (PVL) remains a significant complication, associated with increased mortality. Clinical studies have identified correlations between PVL and both anatomical features and calcification patterns. Numerical simulations, particularly …
de, gr, gb
(code pays fourni par la source)
Accès ouvert
2025
article
OpenAlex
Stefan Oschatz, Selina Schultz, Nicklas Fiedler, Jana Markhoff et autres
Within this work, blending of high molecular weight (HMW) PLLA with HMW polyethylene oxide (PEO) as self-curing biodegradable stent material for potential treatment of Eustachian tube dysfunction (ETD) is reported. Blending with PEO significantly enhances the material’s mechanical properties, enabling the stent …
de
(code pays fourni par la source)
Accès ouvert
2025
article
OpenAlex
Kaitlyn Ann Rose Schroyer, Klaus‐Peter Schmitz, Gunjeeta Raheja, Bin Su et autres
Glioblastoma (GBM, isocitrate dehydrogenase wild-type) is the most common primary malignant brain tumor in adults and is associated with a severely low survival rate. Treatments offer mere palliation and are ineffective, due, in part, to a lack of understanding of the intricate …
us
(code pays fourni par la source)
Accès ouvert
2024
article
OpenAlex
Stefan Siewert, Christoph Brandt-Wunderlich, Felix Streckenbach, Hagen Paetow et autres
Abstract In vitro test setups for simulated application testing are necessary for physician training as well as for development and benchmarking of various devices in interventional neuroradiology. Within the current study, we implemented a test setup for in vitro simulated application testing. …
de
(code pays fourni par la source)