Efstathios Alexopoulos

The Effects of Vitamin E-Coated Membrane Dialyzer Compared to Simvastatin in Patients on Chronic Hemodialysis

Dimitrios Kirmizis, Αikaterini Papagianni, Fani Dogrammatzi, Anna‐Maria Belechri et autres

BACKGROUND: We investigated the effects of the use of vitamin E-coated membrane (VEM) dialyzer in comparison to simvastatin on markers of chronic inflammation, oxidative stress, and endothelial cell apoptosis in ten patients on chronic hemodialysis (HD), aiming at distinguishing the different treatment …

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Steroids and azathioprine in the treatment of IgA nephropathy

Μaria Stangou, Domniki Ekonomidou, Panagiotis Giamalis, Helen Liakou et autres

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Effects of simvastatin on markers of inflammation, oxidative stress and endothelial cell apoptosis in patients on chronic hemodialysis

Dimitrios Kirmizis, Αikaterini Papagianni, Fani Dogrammatzi, Lemonia Skoura et autres

AIM: We investigated the effects of simvastatin on markers of inflammation, oxidative stress and endothelial cell apoptosis in hyperlipidemic endstage renal disease patients on chronic hemodialysis (HD). METHODS: In 25 hyperlipidemic HD patients who received 10 mg of simvastatin for 6 months …

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Is Presence of ANCA in Crescentic IgA Nephropathy a Coincidence or Novel Clinical Entity? A Case Series

Christos Bantis, Μaria Stangou, Christoph Schlaugat, Efstathios Alexopoulos et autres

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Abstract: S4-18 EFFECTS OF SIMVASTATIN ON MARKERS OF INFLAMMATION, ENDOTHELIAL DYSFUNCTION AND APOPTOSIS IN CHRONIC HEMODIALYSIS PATIENTS

Dimitrios Kirmizis, Αikaterini Papagianni, A-M Belechri, Georgios Efstratiadis et autres

Abstract: P1425 ANTI-INFLAMMATORY AND ANTI-OXIDATIVE EFFECTS OF VITAMIN E-COATED MEMBRANE DIALYZER IN CHRONIC HEMODIALYSIS PATIENTS

Dimitrios Kirmizis, Αikaterini Papagianni, A-M Belechri, Georgios Efstratiadis et autres

Urinary levels of epidermal growth factor, interleukin‐6 and monocyte chemoattractant protein‐1 may act as predictor markers of renal function outcome in immunoglobulin A nephropathy

Μaria Stangou, Efstathios Alexopoulos, Αikaterini Papagianni, Afroditi Pantzaki et autres

AIM: Urinary cytokine excretion may reflect histological changes in immunoglobulin A nephropathy (IgAN), and their measurement can give information about disease outcome. METHODS: Thirty-three IgAN patients were prospectively followed for 5.6 +/- 3.1 years. Urinary levels of monocyte chemoattractant protein-1 (MCP-1), interleukin …

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NPHS2 screening with SURVEYOR in Hellenic children with steroid-resistant nephrotic syndrome

Konstantinos Voskarides, Christiana Makariou, Gregory Papagregoriou, Nicolaos Stergiou et autres

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C5b-9 glomerular deposition and tubular α3β1-integrin expression are implicated in the development of chronic lesions and predict renal function outcome in immunoglobulin A nephropathy

Μaria Stangou, Efstathios Alexopoulos, Afroditi Pantzaki, Maria Leonstini et autres

OBJECTIVE: Tubular atrophy is one of the factors predicting poor outcome of renal function in primary immunoglobulin A nephropathy (IgAN). However, the development of tubular atrophy is a late phenomenon during the disease progression. It would be useful to identify early factors …

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Fibrotic Mechanisms in Idiopathic Rapidly Progressive Glomerulonephritis: The Role of TGF-β1 and C5b-9

Lazaros Gionanlis, Efstathios Alexopoulos, Αikaterini Papagianni, Maria Leontsini et autres

BACKGROUND: Idiopathic IRPGN is a form of renal vasculitis in which a high chronicity index is present despite minimal impairment of renal function. The present study investigated the mechanisms underlining the relatively early appearance of fibrosis. METHODS: In all, 34 patients (17 …

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Carotid Atherosclerosis and Endothelial Cell Adhesion Molecules as Predictors of Long-Term Outcome in Chronic Hemodialysis Patients

Αikaterini Papagianni, Spyros Dovas, Christos Bantis, Anna‐Maria Belechri et autres

BACKGROUND/AIMS: Cardiovascular disease (CVD) remains the leading cause of increased morbidity and mortality for hemodialysis (HD) patients. The aim of this study was to investigate the predictive values of carotid artery atherosclerotic lesions and endothelial adhesion molecule levels for long-term outcome in …

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COL4A3/COL4A4 Mutations Producing Focal Segmental Glomerulosclerosis and Renal Failure in Thin Basement Membrane Nephropathy

Konstantinos Voskarides, Loukas Damianou, Vassos Neocleous, Ioanna Zouvani et autres

Mutations in the COL4A3/COL4A4 genes of type IV collagen have been found in approximately 40% of cases of thin basement membrane nephropathy, which is characterized by microscopic hematuria and is classically thought to cause proteinuria and chronic renal failure rarely. Here we …

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