J M Mercader

Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls

T.M. Teslovich, Nancy J. Cox, T D-GENES, M. Laakso et autres

Protein-coding genetic variants that strongly affect disease risk can yield relevant clues to disease pathogenesis. Here we report exome-sequencing analyses of 20,791 individuals with type 2 diabetes (T2D) and 24,440 non-diabetic control participants from 5 ancestries. We identify gene-level associations of rare …

us (code pays fourni par la source)

The First Genome-Wide Association Study (GWAS) for Type 2 Diabetes in Youth from the Progress in Diabetes Genetics in Youth (ProDiGY) Collaboration

Shylaja Srinivasan, Jennifer N. Todd, Ling Chen, Jasmin Divers et autres

The prevalence of type 2 diabetes is increasing in youth, particularly in certain ethnic groups, and studies have highlighted differences between youth- and adult-onset disease. However, its genetic determinants remain largely unexplored. To identify genetic variants predisposing to type 2 diabetes in …

Combination of diffusion tensor and functional magnetic resonance imaging during recovery from the vegetative state

Davinia Fernández‐Espejo, Carme Junqué, Damian Cruse, Montserrat Bernabeu et autres

BACKGROUND: The rate of recovery from the vegetative state (VS) is low. Currently, little is known of the mechanisms and cerebral changes that accompany those relatively rare cases of good recovery. Here, we combined functional magnetic resonance imaging (fMRI) and diffusion tensor …

es, gb (code pays fourni par la source)

Reductions of Thalamic Volume and Regional Shape Changes in the Vegetative and the Minimally Conscious States

Davinia Fernández‐Espejo, Carme Junqué, Montserrat Bernabeu, Teresa Roig-Rovira et autres

The thalamus is known to play a key role in arousal regulation and support of human consciousness. Neuropathological studies have identified thalamic damage as one of the most common abnormalities present in the brains of patients who were in a vegetative state …

es (code pays fourni par la source)

Cistoadenoma gigante de páncreas: Una entidad poco frecuente

M. A. Medranda Gómez, H. Salama Benarroch, R. García Selligrat, J M Mercader et autres

Cistoadenoma gigante de páncreas. Una entidad poco frecuentePalabras clave: Neoplasias quísticas.

es (code pays fourni par la source)

Amygdalar and hippocampal MRI volumetric reductions in Parkinson's disease with dementia

Carme Junqué, Blanca Ramírez‐Ruiz, Eduardo Tolosa, Christopher Summerfield et autres

Parkinson's disease (PD) involves neuropathological changes in the limbic system that lead to neuronal loss and volumetric reductions of several nuclei. We investigated possible volumetric reductions of the amygdala and hippocampus associated to PD. We carried out magnetic resonance imaging (MRI) volumetric …

es (code pays fourni par la source)

P.3.068 Regional gray matter density and correlates of disease severity in panic disorder

Guillem Massana, Pilar Salgado‐Pineda, Josep M. Serra‐Grabulosa, Cristòbal Gastó et autres

fMRI pattern cerebral activation during a face-name encoding task in subjects with antecedents of prematurity

Mònica Giménez, Xavier Caldú, Pilar Salgado‐Pineda, Ana Narberhaus et autres

es (code pays fourni par la source)

Dementia in Parkinson Disease

Christopher Summerfield, Beatriz Gómez‐Ansón, Eduardo Tolosa, J M Mercader et autres

BACKGROUND: Magnetic resonance spectroscopy has been shown to be useful in differentiating idiopathic Parkinson disease (PD) from atypical parkinsonian syndromes such as progressive supranuclear palsy, multiple system atrophy, and corticobasal degeneration. OBJECTIVE: To systematically investigate the utility of proton magnetic resonance spectroscopy …

es (code pays fourni par la source)

Long-term effects of ursodeoxycholic acid in primary biliary cirrhosis: results of a double-blind controlled multicentric trial

Albert Parés, Llorenç Caballería, Juan Rodés, Miquel Bruguera et autres

es (code pays fourni par la source)

Pre-Mammillary Endoscopy: Evaluation with Phase Contrast Cine-MR Imaging

Giulio Zuccoli, Núria Bargalló, J M Mercader, Javier Ibáñez et autres

Cerebrospinal fluid (CSF) waveform evaluation through the use of Phase Contrast Cine-Magnetic Resonance (MR) imaging after pre-mammillary endoscopic ventriculostomy. A descriptive study of 21 patients, 13 men and 8 women (average age 36), submitted to pre-mammillary endoscopic ventriculostomy for treatment of non-communicating …

it, es, us (code pays fourni par la source)

Metadoxine accelerates fatty liver recovery in alcoholic patients: results of a randomized double-blind, placebo-control trial

Joan Caballería, Albert Parés, Concepció Brú, J M Mercader et autres

es (code pays fourni par la source)