Pieter C F Stokkers

IBD-specific Cognitive Behavioral Therapy: Sustainability of effect after three years

Floor Bennebroek Evertsz, Florentine L. S. Goes, Pieter C F Stokkers, Robbert Sanderman et autres

Background and Aims ‘Inflammatory Bowel Disease (IBD)-specific-Cognitive-Behavioral Therapy’ (CBT) is effective in improving Quality of Life (QoL) and in decreasing anxiety and depression in IBD-patients with poor mental QoL, one month after completing CBT. Main aim was to examine the sustainability of …

nl (code pays fourni par la source)

Appendicectomy plus standard medical therapy versus standard medical therapy alone for maintenance of remission in ulcerative colitis (ACCURE): a pragmatic, open-label, international, randomised trial

Yaïr I. Z. Acherman, Naila Arebi, Elizabeth Arthurs, Willem A. Bemelman et autres

BACKGROUND: The appendix might have an immunomodulatory role in ulcerative colitis. Appendicectomy has been suggested as a potentially therapeutic intervention to maintain remission in ulcerative colitis. We aimed to evaluate the clinical effectiveness of laparoscopic appendicectomy in maintaining remission in patients with …

Using Participatory Narrative Inquiry to Assess Experiences and Self-Experimentation with Diet Interventions in Inflammatory Bowel Disease Patients

Celine Hos, Merel Tebbens, Tjitske Bezema, Jos A. Bosch et autres

BACKGROUND AND AIMS: To improve quality of life (QoL), patients with inflammatory bowel diseases (Crohn's disease and ulcerative colitis) often self-experiment with lifestyle changes such as dietary modifications. The nature (e.g., type of interventions, expectations, perceived efficacy) of these single-subject experiments has …

nl, us (code pays fourni par la source)

DAMP-ing IBD: Extinguish the Fire and Prevent Smoldering

Oliver Sandys, Pieter C F Stokkers, Anje A. te Velde

In inflammatory bowel diseases (IBD), the most promising therapies targeting cytokines or immune cell trafficking demonstrate around 40% efficacy. As IBD is a multifactorial inflammation of the intestinal tract, a single-target approach is unlikely to solve this problem, necessitating an alternative strategy …

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FIRST REAL WORLD EVIDENCE IN THE NETHERLANDS EVALUATING THE EFFICACY AND EFFICIENCY OF A NEW SEDATIVE REMIMAZOLAM COMPARED WITH MIDAZOLAM IN PATIENTS UNDERGOING COLONOSCOPY OR GASTROSCOPY

Jorn Krijnen, Pieter C F Stokkers, Jeroen M. Jansen

FIRST REAL WORLD EVIDENCE IN THE NETHERLANDS EVALUATING THE EFFICACY AND EFFICIENCY OF A NEW SEDATIVE REMIMAZOLAM COMPARED WITH MIDAZOLAM IN PATIENTS UNDERGOING COLONOSCOPY OR GASTROSCOPY

Jorn Krijnen, Pieter C F Stokkers, Jeroen M. Jansen

FIRST REAL WORLD EVIDENCE IN THE NETHERLANDS EVALUATING THE EFFICACY AND EFFICIENCY OF A NEW SEDATIVE REMIMAZOLAM COMPARED WITH MIDAZOLAM IN PATIENTS UNDERGOING COLONOSCOPY OR GASTROSCOPY

Jorn Krijnen, Pieter C F Stokkers, Jeroen M. Jansen

Electronic Nose Sensor Drift Affects Diagnostic Reliability and Accuracy of Disease-Specific Algorithms

Sofie Bosch, Renée X. de Menezes, Suzanne Orhan Pees, Dion J. Wintjens et autres

Sensor drift is a well-known disadvantage of electronic nose (eNose) technology and may affect the accuracy of diagnostic algorithms. Correction for this phenomenon is not routinely performed. The aim of this study was to investigate the influence of eNose sensor drift on …

nl (code pays fourni par la source)

Integration of stool microbiota, proteome and amino acid profiles to discriminate patients with adenomas and colorectal cancer

Sofie Bosch, Animesh Acharjee, Mohammed Nabil Quraishi, Irene V. Bijnsdorp et autres

BACKGROUND: Screening for colorectal cancer (CRC) reduces its mortality but has limited sensitivity and specificity. Aims We aimed to explore potential biomarker panels for CRC and adenoma detection and to gain insight into the interaction between gut microbiota and human metabolism in …

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The potential of fecal microbiota and amino acids to detect and monitor patients with adenoma

Sofie Bosch, Animesh Acharjee, Mohammed Nabil Quraishi, Patricia Guzmán Rojas et autres

The risk of recurrent dysplastic colonic lesions is increased following polypectomy. Yield of endoscopic surveillance after adenoma removal is low, while interval colorectal cancers occur. To longitudinally assess the dynamics of fecal microbiota and amino acids in the presence of adenomatous lesions …

ca, nl, gb, it (code pays fourni par la source)

Healthy Cotwins Share Gut Microbiome Signatures With Their Inflammatory Bowel Disease Twins and Unrelated Patients

Eelco Christiaan Brand, Marjolein A. Y. Klaassen, Ranko Gaćeša, Arnau Vich Vila et autres

BACKGROUND & AIMS: It is currently unclear whether reported changes in the gut microbiome are cause or consequence of inflammatory bowel disease (IBD). Therefore, we studied the gut microbiome of IBD-discordant and -concordant twin pairs, which offers the unique opportunity to assess …

nl (code pays fourni par la source)

Hypnotherapy for Irritable Bowel Syndrome-Type Symptoms in Patients with Quiescent Inflammatory Bowel Disease: A Randomized, Controlled Trial

Daniël R. Hoekman, Arine M. Vlieger, Pieter C F Stokkers, Nofel Mahhmod et autres

BACKGROUND AND AIMS: Many inflammatory bowel disease [IBD] patients in remission have persisting symptoms, compatible with irritable bowel syndrome [IBS-type symptoms]. We aimed to compare the effectiveness of gut-directed hypnotherapy vs standard medical treatment [SMT] for IBS-type symptoms in IBD patients. METHODS: …

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