Jörg Schirra

Diagnostic accuracy and Patient Derived Organoid (PDO) yield of 19G vs 22G Franseen needles for EUS-Guided biopsy in solid pancreatic lesions: A prospective comparative study

Sarah Klauss, Yonggan Xue, Ahmed Alnatsha, Prince Allawadhi et autres

BACKGROUND/OBJECTIVES: Endoscopic ultrasound-guided fine needle biopsy (EUS-FNB) is the standard procedure for conducting histological assessment of solid pancreatic lesions and obtaining tissue cores for generating patient-derived organoids (PDOs) in unresectable patients. The aim of this single-institution, prospective, comparative study was to investigate …

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Multicentre randomised controlled trial of a self-assembling haemostatic gel to prevent delayed bleeding following endoscopic mucosal resection (PURPLE Trial)

J. Drews, Markus Zachäus, Tobias Kleemann, Jörg Schirra et autres

BACKGROUND: Prophylactic application of a haemostatic gel to the resection field may be an easy way to prevent delayed bleeding, a frequent complication after endoscopic mucosal resection (EMR). OBJECTIVE: We aimed to evaluate if the prophylactic application of a haemostatic gel to …

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Severity of Gallstone-, Sludge-, or Microlithiasis-Induced Pancreatitis—All of the Same?

Simon Sirtl, Katharina Bretthauer, Mahmood Ahmad, Eric Hohmann et autres

BACKGROUND/AIM: Severity of microlithiasis- and sludge-induced pancreatitis in comparison to gallstone-induced pancreatitis has never been studied for a lack of definition. MATERIALS AND METHODS: In this retrospective cohort study, 263 patients with acute biliary pancreatitis treated at a tertiary care center from …

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Interstitial and Intraluminal Photodynamic Therapy – The Munich Experiences

Ronald Sroka, Maximilian Aumiller, Maria Apfelbeck, Mohamed El Fahim et autres

Different clinical aspects of photodynamic therapy (PDT), like treatment planning, treatment and dosimetry protocols, spectral on-line-monitoring (SOM) as well as follow-up evaluation of clinical outcome, are of interest regarding further iPDT developments. For three specific applications, interstitial PDT (iPDT) for prostate cancer …

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Assemblage of a functional and versatile endoscopy trainer reusing medical waste: Step‐by‐step video tutorial

Riccardo Vasapolli, Jörg Schirra, Christian Schulz

Watch a video of this article.

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Pankreaszysten – Indikationen, Zeitpunkt und Rationale für eine Surveillance

Marlies Vornhülz, Simon Sirtl, Elisabeth Orgler, Maximilian Weniger et autres

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A machine-learning based decision tool selecting patients with idiopathic acute pancreatitis for endosonography to exclude a biliary aetiology

Simon Sirtl, Michał Żorniak, Georg Beyer, Eric Hohmann et autres

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Biliary sludge, microlithiasis and gallstone-induced acute pancreatitis are associated with comparable clinical outcome: a single-centre analysis and narrative review of the literature

Simon Sirtl, Katharina Bretthauer, Eric Hohmann, Mahmood Ahmad et autres

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Machine learning-based decision tool for selecting patients with idiopathic acute pancreatitis for endosonography to exclude a biliary aetiology

Simon Sirtl, Michał Żorniak, Eric Hohmann, Georg Beyer et autres

BACKGROUND: Biliary microlithiasis/sludge is detected in approximately 30% of patients with idiopathic acute pancreatitis (IAP). As recurrent biliary pancreatitis can be prevented, the underlying aetiology of IAP should be established. AIM: To develop a machine learning (ML) based decision tool for the …

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Microscopic alterations of the gastric mucosa in preneoplastic lesions as assessed by new-generation endocytoscopy

Riccardo Vasapolli, Lukas Neuhaus, Jörg Schirra, Jens Neumann et autres

Chronic atrophic gastritis with/without intestinal metaplasia is defined as a gastric precancerous condition (GPC) that increases the risk of gastric cancer according to the severity of atrophy [ 1 ]. Advanced endoscopic imaging permits accurate visualization of the mucosa and optical diagnosis …

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Evidence of Endoscopic and Interventional Treatment of Chronic Pancreatitis and Pseudocysts

Jörg Schirra, Simon Sirtl, Markus M. Lerch, Julia Mayerle

In patients with chronic pancreatitis burdened with a high comorbidity endoscopic therapy can provide short-term relief of symptoms. In many instances the benefit of endoscopic therapy is transient and repeated interventions are necessary. Endotherapy is the first line of management in chronic …

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Biliäre Mikrolithiasis und Sludge mit Gallenstein-äquivalenten Pankreatitis-Outcome

Simon Sirtl, Katharina Bretthauer, Eike Hohmann, Masood Ahmad et autres

Einleitung Biliärer Sludge und Mikrolithiasis gelten seit Jahrzehnten als wichtigste ätiologische Treiber innerhalb der Kohorte der idiopathischen akuten Pankreatitis. Die Subsumierung der Mikrolithiasis- und Sludge-induzierten Pankreatitis Patienten in die Kohorten der idiopathischen oder Gallenstein-induzierten akuten Pankreatitis machte eine adäquate Risikobewertung bisher jedoch …

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