Jean-Valéry C. E. Coumans

United against racism: enhancing access and patient experience for black and Hispanic patients in Neuro-oncological care

Emmy Duerr, Rishab Ramapriyan, Emmanuel Mensah, Jasmine Gabriel Hughes et autres

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ROCK-dependent mechanotransduction of macroscale forces drives fibrosis in degenerative spinal disease

Muhamed Hadzipasic, Margaret S. Sten, Elie Massaad, Ali Kiapour et autres

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495 Delineating Growth Dynamics and Surgical Indicators in VHL-Associated and Sporadic Hemangioblastomas

Shahaan S. Razak, Timothy R. West, Amy J. Wang, Ethan Wetzel et autres

INTRODUCTION: Hemangioblastomas, especially those with von Hippel-Lindau (VHL) disease, exhibit variable clinical trajectories, ranging from prolonged stability to aggressive growth necessitating surgical intervention. METHODS: We retrospectively identified patients with intracranial hemangioblastomas resected between 2000 and 2022 at a single institution. Patient demographics, …

Disparities in Surgical Intervention and Health-Related Quality of Life Among Racial/Ethnic Groups With Degenerative Lumbar Spondylolisthesis

Elie Massaad, Taylor Mitchell, Emmy Duerr, Ali Kiapour et autres

BACKGROUND AND OBJECTIVES: Racial and socioeconomic disparities in spine surgery for degenerative lumbar spondylolisthesis persist in the United States, potentially contributing to unequal health-related quality of life (HRQoL) outcomes. This is important as lumbar spondylolisthesis is one of the most common causes …

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1077 Operative Management and Outcomes in Spinal Hemangioblastoma: A Multi-institutional Case Series of 59 Patients

Sarah E. Blitz, Gabriel N. Friedman, Jean-Valéry C. E. Coumans, John H. Shin et autres

INTRODUCTION: Hemangioblastoma is a rare benign neoplasm that accounts for 2-5% of all spinal cord tumors and is associated with von-Hippel Landau (VHL) disease in about 25-30% of patients. Symptomatic spinal hemangioblastomas are typically managed with en bloc microsurgical resection, but the …

429 Sub-internship Academy: Implementation and Evaluation of Single-Day Resident-Driven Focused Sub-internship Preparation Course

Zsombor Tamas Gal, Pranav Nanda, Brian Hsueh, Faith C. Robertson et autres

INTRODUCTION: Strong performance in neurosurgical sub-internships requires familiarity with clinical and technical skills which may not otherwise be covered in standard medical school curricula. Thus, a need exists for immersive and comprehensive sub-internship preparation programs, which should be optimized based on student …

Neurological Surgery Residency Programs in the United States: A National Cross-Sectional Survey

Patrick R. Ng, Alexander G. Yearley, Tiffany Alyssa Eatz, Sonia Ajmera et autres

BACKGROUND AND OBJECTIVES: The Accreditation Council for Graduate Medical Education has approved 117 neurological surgery residency programs which develop and educate neurosurgical trainees. We present the current landscape of neurosurgical training in the United States by examining multiple aspects of neurological surgery …

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Belzutifan treatment of Von Hippel-Lindau (VHL) related central nervous system (CNS) hemangioblastomas (HBs): A single institution experience.

Othon Iliopoulos, Otto Rapalino, Frederick George Barker, Jean-Valéry C. E. Coumans et autres

2078 Background: Patients with inactivating germline mutations in the VHL gene develop CNS (brain and/or spine) HBs and/or renal cancers, pheochromocytomas and pancreatic neuroendocrine tumors. The oral HIF2a inhibitor belzutifan has been approved by FDA for the treatment of VHL-related HBs. We …

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In Reply: Congenitally Fused Cervical Spine is Associated With Adjacent-Level Degeneration in the Absence of Cervical Spine Surgery

Gabriel N. Friedman, Jean-Valéry C. E. Coumans

To the Editor: We thank Dr Goel for his letter regarding our article1,2 detailing adjacent segment degeneration in the cervical spine in patients with congenital cervical fusion. It is certainly intriguing to consider the hypothesis that spinal segmental fusion is always secondary. …

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322 Distributed Vector Representations of Neurosurgical Admission Notes Predict Discharge Disposition

Arjun Khanna, Jean-Valéry C. E. Coumans

INTRODUCTION: Natural language processing (NLP) aims to extract information from unstructured language input for use in machine learning, without the need for laborious manual review of text to retrieve data of potential interest. An NLP-based model utilizing term frequency-inverse document frequency (TF-IDF) …

486 Macroscale Forces Drive Targetable Microscale Fibrotic Mechanosensing in Degenerative Spinal Disease

Muhamed Hadzipasic, Margaret Sten, Elie Massaad, Ali Kiapour et autres

INTRODUCTION: Mechanical forces are emerging as key drivers of fibrosis. Elucidating this pathophysiology is relevant in degenerative spinal disease (DSD) where mechanical stress on the spine is associated with fibrotic changes in ligament and bone, with resultant compression of the neural elements. …

Applying objective metrics to neurosurgical skill development with simulation and spaced repetition learning

Faith C. Robertson, Christopher J. Stapleton, Jean-Valéry C. E. Coumans, Federico Nicolosi et autres

OBJECTIVE: Surgical skills laboratories augment educational training by deepening one's understanding of anatomy and allowing the safe practice of technical skills. Novel, high-fidelity, cadaver-free simulators provide an opportunity to increase access to skills laboratory training. The neurosurgical field has historically evaluated skill …

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