Brian Hsueh

Tumor infiltrating lymphocytes in glioblastoma: immunobiology and translational implications

Cameron M. Hill, Chibueze D. Nwagwu, Angel O. Odukoya, Brian Hsueh et autres

Glioblastoma (GBM) poses unique challenges to immunotherapy, owing to its low tumor mutational burden, profound antigenic heterogeneity, and highly immunosuppressive microenvironment. Observations of tumor-infiltrating lymphocytes (TILs) in human GBM differ from those in syngeneic orthotopic murine models: whereas TILs in several widely …

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Immunotherapy and targeted therapy for high grade gliomas: current and future directions

Brian Hsueh, Samuel J. Steuart, Briana C. Prager, Young Joon Kim et autres

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Early exposure to neurosurgery: promoting early specialty interest through a single-day resident-driven neurosurgical course for preclinical students

Nicole A Perez, Zsombor Tamas Gal, William Muñoz, Brian Hsueh et autres

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Immunologic specificity in glioblastoma: Antigen discovery and translational implications

Cameron M. Hill, Anthony Z. Wang, Brian Hsueh, Ngima D. Sherpa et autres

Recent studies have highlighted the therapeutic potential of targeting tumor antigens (TAs) in glioblastoma (GBM). Several classes of TAs, such as tumor-associated, cancer testis, and tumor-specific antigens, have proven to be immunogenic and used safely in vaccines. Many of these vaccines have …

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Sub-Internship Academy: Implementation and Evaluation of Single-Day Resident-Driven Focused Sub-Internship Preparation Course

Zsombor Tamas Gal, Pranav Nanda, Brian Hsueh, Faith C. Robertson et autres

OBJECTIVE: Strong performance in neurosurgical sub-internships is a vital component of a successful residency application and requires adequate familiarity with clinical knowledge and technical skills that may not be covered in standard medical school curricula. Accordingly, a need exists for immersive and …

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Immunotherapy for Brain Tumors: Where We Have Been, and Where Do We Go From Here?

Alexander F. Wang, Brian Hsueh, Bryan D. Choi, Elizabeth Robins Gerstner et autres

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429 Sub-internship Academy: Implementation and Evaluation of Single-Day Resident-Driven Focused Sub-internship Preparation Course

Zsombor Tamas Gal, Pranav Nanda, Brian Hsueh, Faith C. Robertson et autres

INTRODUCTION: Strong performance in neurosurgical sub-internships requires familiarity with clinical and technical skills which may not otherwise be covered in standard medical school curricula. Thus, a need exists for immersive and comprehensive sub-internship preparation programs, which should be optimized based on student …