M Petkova

Clinical Relevance of Anti-C3 and Anti-C4 Autoantibodies in Lupus Nephritis

Vasil V. Vasilev, Mikel Rezola Artero, M Petkova, Galya Mihaylova et autres

Introduction: Complement system overactivation is pivotal in lupus nephritis (LN) pathophysiology. Considering that anti-C3 autoantibodies play a significant role in LN pathophysiology, we explored them as disease activity biomarkers and compared them to the ones against the homologous protein, C4. Methods: = …

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[A rare case of Itsenko-Cushing disease accompanied by gangrene of the fingers and cryoglobulinemia].

M Petkova, Andrey Manov, M Baleva, A Tsanev

A case of a woman with Itsenko [correction of Icenko]-Cushing's disease and a rare complication--necrosis of the fingers of the left hand--is presented. Besides the known factors of hypercorticism injuring the vascular wall, cryoglobulinemia was found in the patient. It is probably …

[Case of primary hypogonadism in congenital dyskeratosis: Zinsser-Cole-Engmann syndrome].

M Petkova, A Tsanev

A rare case is described with congenital dermatosis, leading to systemic lesions of epithelium of skin and mucose, combined with primary hypogonadism. A very low level of testosterone was established with high gonadotropic hormones and prolactin. Hypogonadism was established to be the …