Ryohei Nishino

Rapidly Progressive Diffuse Alveolar Damage Following Transbronchial Lung Biopsy in a Patient with Lung Adenocarcinoma: An Autopsy Case Report

Hiromi Idehata, Yu Nakanishi, Aoi Kurihara, Sora Mishima et autres

An 80-year-old man with a persistent cough underwent chest computed tomography, which revealed a pulmonary mass with subtle ground-glass opacities. A transbronchial lung biopsy confirmed lung adenocarcinoma. Shortly after bronchoscopy, the patient developed rapidly progressive hypoxemic respiratory failure, consistent with acute respiratory …

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Pathogenic role of IFNγ from activated CD4+ T cells in lupus model mice induced by topical treatment with toll-like receptor agonist imiquimod

Reona Tanimura, Yuya Kondo, Ryota Sato, Ryohei Nishino et autres

Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by multiple organ involvement. It is known that cytokines produced from activated CD4+ T cells play a pivotal role in the development of SLE; however, the details of pathological processes remain unclear. The …

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Allergic Bronchopulmonary Mycosis Caused by Nigroporus vinosus

Yu Nakanishi, Takashi Kei SAITO, Shoshi Akieda, Ryohei Nishino et autres

Allergic bronchopulmonary mycosis (ABPM) is a chronic respiratory disease in which saprophytic fungi grow in the airways of adults and induce types I and III allergic reactions. ABPM is often caused by Aspergillus spp.; however, data on non-Aspergillus ABPM are limited. The …

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Diffuse Large B-cell Lymphoma Arising from Middle Mediastinum with Severe Endobronchial Involvement: A Case Report

Tai Okusaki, Yu Nakanishi, Yutaro Takata, Masako Watanabe et autres

Diffuse large B-cell lymphoma (DLBCL) commonly presents at various anatomical sites. However, primary involvement of the middle mediastinum is rare. We report a 72-year-old male who presented with progressive dyspnea due to severe bronchial obstruction caused by a middle mediastinal mass. Bronchoscopic …

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Effect of Cu on Solidification Microstructure and Solidification Process in High Carbon High Speed Steel Type Cast Alloy

Yuki Tanaka, Ryohei Nishino, Kazunori Kamimiyada, Kohei Morishita et autres

Effect of copper on solidification microstructure and solidification process were investigated for high carbon high speed steel type alloys (Fe-2.0%C-5%Cr-5%Mo-5%V-0~7.5%Cu in mass%). The microstructure of all as-cast specimens with different copper content is dendrite consisting mainly of primary γ, MC-γ eutectic and …

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Influence of Mo and W on Solidification Microstructure Formation for Ni-hard Type Cast Iron

Ryohei Nishino, Yūki Tanaka, Kazunori Kamimiyada, Kohei Morishita et autres

The solidification microstructure of Ni-hard type cast iron was investigated to evaluate the influence of Mo and W additions on the formation of carbides and graphite. The specimen was prepared based on the composition of Fe-3.3%C-0.8%Si-0.8%Mn-4.4%Ni in mass%, and Mo or W …

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Effect of Cu on Solidification Microstructure and Solidification Process in High Carbon High Speed Steel Type Cast Alloy

Yuki Tanaka, Ryohei Nishino, Kazunori Kamimiyada, Kohei Morishita et autres

Effect of copper on solidification microstructure and solidification process were investigated for high carbon high speed steel type alloys (Fe-2.0%C-5%Cr-5%Mo-5%V-0~7.5%Cu in mass%). The microstructure of all as-cast specimens with different copper content is dendrite consisting mainly of primary γ, MC-γ eutectic and …

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Supplementary Figure Legend from RASEF is a Novel Diagnostic Biomarker and a Therapeutic Target for Lung Cancer

Hideto Oshita, Ryohei Nishino, Atsushi Takano, Takashi Fujitomo et autres

PDF file - 61K

Supplementary Tables 1 - 2 from RASEF is a Novel Diagnostic Biomarker and a Therapeutic Target for Lung Cancer

Hideto Oshita, Ryohei Nishino, Atsushi Takano, Takashi Fujitomo et autres

PDF file - 113K, Supplementary Table S1. Lung cancer cell lines used in analysis. Supplementary Table S2. Background of lung cancer patients analyzed by tissue microarray (n=341).

Supplementary Figures 1 - 6 from RASEF is a Novel Diagnostic Biomarker and a Therapeutic Target for Lung Cancer

Hideto Oshita, Ryohei Nishino, Atsushi Takano, Takashi Fujitomo et autres

PDF file - 2714K, S1. Western blot analysis with anti-RASEF antibody after phosphatase treatment of NCI-H2170 cells. S2. Kaplan-Meier analysis of tumor-specific survival of surgically treated NSCLC patients (n = 341) according to expression levels of RASEF. Markers on survival curves mean …

Data from RASEF is a Novel Diagnostic Biomarker and a Therapeutic Target for Lung Cancer

Hideto Oshita, Ryohei Nishino, Atsushi Takano, Takashi Fujitomo et autres

Abstract Genome-wide gene expression profiling revealed that the Ras and EF-hand domain containing (RASEF) transcript was significantly transactivated in the majority of lung cancers. Using lung cancer cells, transient expression of RASEF promoted cell growth, whereas RASEF knockdown not only reduced its …

Data from RASEF is a Novel Diagnostic Biomarker and a Therapeutic Target for Lung Cancer

Hideto Oshita, Ryohei Nishino, Atsushi Takano, Takashi Fujitomo et autres

Abstract Genome-wide gene expression profiling revealed that the Ras and EF-hand domain containing (RASEF) transcript was significantly transactivated in the majority of lung cancers. Using lung cancer cells, transient expression of RASEF promoted cell growth, whereas RASEF knockdown not only reduced its …