Sam Groves

Infliximab versus ciclosporin in steroid resistant acute severe ulcerative colitis: a model-based cost-utility analysis of data from CONSTRUCT pragmatic trial

M Fasihul Alam, Mirella Longo, David R. Cohen, Sam Groves et autres

BACKGROUND: There is limited evidence in the literature on the long-term effectiveness and cost-effectiveness of treatments for Acute Severe Ulcerative Colitis (ASUC). The study aimed to perform decision analytic model-based long-term cost-utility analysis (CUA) of infliximab versus ciclosporin for steroid-resistant ASUC investigated …

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Overweight/Obesity and Time Preference: Evidence from a Survey among Adults in the UK

Morro Touray, David R. Cohen, Simon Robert Pask Williams, M Fasihul Alam et autres

INTRODUCTION: Overweight and obesity is a global problem incurring substantial health and economic implications. This has also been highlighted by the ongoing COVID-19 pandemic which has disproportionately affected overweight and obese individuals. Most of the interventions have concentrated on promotion of physical …

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A multicentre randomised feasibility STUdy evaluating the impact of a prognostic model for Management of BLunt chest wall trauma patients: STUMBL Trial

Ceri Elisabeth Battle, Hayley Anne Hutchings, Timothy Driscoll, Claire O’Neill et autres

Objective A new prognostic model has been developed and externally validated, the aim of which is to assist in the management of the blunt chest wall trauma patient in the emergency department (ED). The aim of this trial is to assess the …

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Home-based pre-surgical psychological intervention for knee osteoarthritis (HAPPiKNEES): a feasibility randomized controlled trial

Roshan das Nair, Jacqueline R. Mhizha-Murira, Pippa Anderson, Hannah Carpenter et autres

OBJECTIVE: To determine the feasibility of conducting a trial of a pre-surgical psychological intervention on pain, function, and mood in people with knee osteoarthritis listed for total knee arthroplasty. DESIGN: Multi-centre, mixed-methods feasibility randomized controlled trial of intervention plus usual care versus …

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12 A multi-centre randomised feasibility study evaluating the impact of a prognostic model for management of blunt chest wall trauma patients: stumbl trial

Ceri Elisabeth Battle, Hayley Anne Hutchings, Zoe Abbott, Claire O’Neill et autres

Introduction A new prognostic model has been developed and externally validated, the aim of which is to assist in the management of the blunt chest wall trauma patient in the Emergency Department (ED). A definitive randomised controlled trial (impact trial), is required …

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Protocol for a multicentre randomised feasibility STUdy evaluating the impact of a prognostic model for Management of BLunt chest wall trauma patients: STUMBL trial

Ceri Elisabeth Battle, Zoe Abbott, Hayley Anne Hutchings, Claire O’Neill et autres

INTRODUCTION: A new prognostic model has been developed and externally validated, the aim of which is to assist in the management of the blunt chest wall trauma patient in the emergency department (ED). A definitive randomised controlled trial (impact trial) is required …

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Prioritisation of specialist health care services; not NICE, not easy but it can be done

Pippa Anderson, Philip Webb, Sam Groves

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A synthesis of field-based application areas of ‘low impact’ group support

Tony E. Gear, Sam Groves, Martin J. Read

This paper is focused on a review of application areas of one form of group support system (GSS), based on the use of wireless handsets, which we have termed ‘low impact’ in type. Our aim is two-fold: to inform understanding of how …

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Antibiotic prescribing and associated diarrhoea: a prospective cohort study of care home residents

David Ch. Gillespie, Kerenza Hood, Antony J. Bayer, Ben Carter et autres

BACKGROUND: the risk factors for and frequency of antibiotic prescription and antibiotic-associated diarrhoea (AAD) among care home residents are unknown. AIM: to prospectively study frequency and risks for antibiotic prescribing and AAD for care home residents. DESIGN AND SETTING: a 12-month prospective …

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A national Programme Budgeting and Marginal Analysis (PBMA) of health improvement spending across Wales: disinvestment and reinvestment across the life course

Rhiannon Tudor Edwards, Joanna Mary Charles, Sara Thomas, Julie Bishop et autres

BACKGROUND: Wales faces serious public health challenges, with relatively low life expectancies and wide inequalities in life expectancy with associated pressures on the National Health Service (NHS) at a time of financial recession. This has led to growing recognition of the need …

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Developing Conversations

Martin J. Read, Tony E. Gear, Sam Groves

This paper explores the process of supporting learning through the use of a ‘low impact' Group Support System (GSS) based on handset technology. The protocol used is described and a conceptual framework is proposed with which to explain practice. The framework centres …

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Continuity of care in the transition from child to adult diabetes services: A realistic evaluation study

Davina A. Allen, David R. Cohen, Christine Atwell, Claire Lane et autres

OBJECTIVES: To identify the continuity mechanisms central to a smooth transition from child to adult diabetes care, the service components through which these can be achieved and their inter-relations in different contexts. METHODS: A realistic evaluation study of five models of transition …

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