Hua Xie

Nasal Continuous Positive Airway Pressure vs Nasal Intermittent Positive Pressure Ventilation in Preterm Infants With Respiratory Distress Syndrome

Hui Zhang, Yijia Zhang, L Zeng, Xiaomei Tong et autres

Importance: Respiratory distress syndrome (RDS) remains a leading cause of morbidity and mortality in preterm infants. Evidence regarding the optimal initial noninvasive ventilation (NIV) mode for extremely preterm infants (<30 weeks' gestation) with RDS is inconsistent. Objective: To determine whether nasal continuous …

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Genome-wide identification and functional characterization of six ERD6-like genes involved in soluble sugar accumulation and response to drought in peach (Prunus persica)

Yanfu Jing, Yuexin Liu, Yaoguang Xu, Yanyan Su et autres

Soluble sugars are key determinants of fruit quality, contributing to the desirable flavors of fruit crops such as peach. Our previous research identified PpERDL16 (early response to dehydration 6-like) as a negative regulator of fructose content in peach fruits. The current study …

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Successful Pregnancy and Healthy Baby Outcome in a Patient With Tyrosine Kinase Inhibitor–Refractory ALK-Positive NSCLC and Central Nervous System Metastasis Treated With Lorlatinib With Maternal-Fetal Pharmacokinetics and Child Milestone Development Correlations

Zhuoran Yao, Min Tang, Ying Jin, Jie Ruan et autres

INTRODUCTION: Lorlatinib is the preferred first-line treatment for advanced ALK+ (ALK+) NSCLC on the basis of the 5-year CROWN update. However, the effects of lorlatinib on the fetus and neonate remain unknown. METHODS: We report the first case of a patient with …

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Occult epidermal growth factor receptor-mutant lung adenocarcinoma complicated by prostatic metastasis: a case report

Fan Yang, Hua Xie, Yajie Zhu, Yi Wang et autres

Herein, we report a case of occult epidermal growth factor receptor (EGFR)-mutant lung adenocarcinoma complicated by prostatic metastasis. A 75-year-old male with >30 years of smoking history presented with lower back pain as the initial symptom. Respiratory symptoms, including cough and sputum …

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Tetrazolium iridium complexes as potential antibacterial agents

Yifei Lü, Xiu Juan Zhang, Minmin Song, Hua Xie et autres

TAZ showed the best antimicrobial activity and the most effective hemolytic performance, which may pave the way to explore the value of the complexes for clinical applications in the future.

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A few-shot learning framework for the diagnosis of osteopenia and osteoporosis using knee X-ray images

Hua Xie, Chenqi Gu, Wenchao Zhang, Jiacheng Zhu et autres

OBJECTIVE: We developed a few-shot learning (FSL) framework for the diagnosis of osteopenia and osteoporosis in knee X-ray images. METHODS: Computer vision models containing deep convolutional neural networks were fine-tuned to enable generalization from natural images (ImageNet) to chest X-ray images (normal …

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3D printing of melatonin-loaded esophageal stents for treatment of corrosive esophagitis

Tianyu Yuan, Dongdong Liu, Qian Li, Wei Meng et autres

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So many measures in ERAS protocol: Which matters most?

Nan Xie, Hua Xie, Wei Li, Zhongxian Zhu et autres

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The combined application of Bacillus velezensis BCP6 and Jinggangmycin (JGM) to control soft rot caused by Pectobacterium aroidearum on Amorphophallus konjac

Mengjia Zhu, Siyuan Ren, Changlong Chen, Yu Ting Tian et autres

Amorphophallus spp. is an important group of crop and medicinal plants, but it is susceptible to infection by soft rot disease during both field growth and storage stages. This results in huge economic and yield losses, which must be properly addressed. Combined …

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A nomogram for predicting death for infants born at a gestational age of <28 weeks: a population-based analysis in 18 neonatal intensive care units in northern China

Xiaofang Huang, Shuaijun Li, Qi Feng, Xiuying Tian et autres

Background: In China, the number of preterm infants is the second largest globally. Compared with those in developed countries, the mortality rate and proportion of treatment abandonment for extremely preterm infants (EPIs) are higher in China. It would be valuable to conduct …

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Focal to bilateral tonic–clonic seizures predict pharmacoresistance in focal cortical dysplasia–related epilepsy

Phat Ly Chang, Hua Xie, Venkata Sita Priyanka Illapani, Xiaozhen You et autres

OBJECTIVE: Focal cortical dysplasia (FCD) is the most common etiology of surgically-remediable epilepsy in children. Eighty-seven percent of patients with FCD develop epilepsy (75% is pharmacoresistant epilepsy [PRE]). Focal to bilateral tonic-clonic (FTBTC) seizures are associated with worse surgical outcomes. We hypothesized …

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Current Status in Rechallenge of Immunotherapy

Han Hwa Hu, Ke Wang, Rong Jia, Zixun Zeng et autres

The treatment of malignant tumors has entered the era of immunotherapy, and immune checkpoint inhibitors (ICIs) have brought significant benefits to patients. However, some patients are required to discontinue treatment with ICIs owing to factors such as disease progression and intolerable side …

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