Y. Ville

Maternal-Fetal Letermovir Exposure In Vivo and Physiologically Based Pharmacokinetic Modeling: A Rationale for Congenital Cytomegalovirus Therapy

Valentine Faure‐Bardon, Naïm Bouazza, Gilles Peytavin, Minh Hoang Le et autres

BACKGROUND: Cytomegalovirus (CMV) affects 0.5%-2.0% of all live births and is the main nongenetic cause of congenital sensorineural hearing loss and neurological damage, yet no validated prenatal treatment exists for infected fetuses. Letermovir, a CMV-specific antiviral, is approved for prophylaxis in transplant …

fr (code pays fourni par la source)

Parental Choices Following Prenatal Diagnosis and Neonatal Mortality Trends: A Population‐Based Analysis

Nicolas Bourgon, Elsa Kermorvant‐Duchemin, Philippe Roth, Alexandre Lapillonne et autres

fr (code pays fourni par la source)

Cytomegalovirus universal screening in early pregnancy: truth is a tendency

Guillaume Favre, Nicolas Bourgon, Philippe Roth, Christos Chatzakis et autres

The data that support the findings of this study are available in Le rapport médical et scientifique procréation et génétique at https://rams.agence-biomedecine.fr/. These data were derived from the following resources available in the public domain: - 2023 data, https://rams.agence-biomedecine.fr/ – 2011-2022 data, …

fr (code pays fourni par la source)

WS06.02Pharmacology of fetal therapy in cystic fibrosis. Report from the MODUL-CF study

A.-S. Bonnel, Tiphaine Bihouée, I. Sermet-Gaudelus, Mélanie Ribault et autres

P091 Pharmacokinetic of elexacaftor/tezacaftor/ivacaftor in the context of fetal cystic fibrosis therapy

N.H. Truong, S. Benaboud, Paulette Magnas, A.-S. Bonnel et autres

fr (code pays fourni par la source)

Prévention secondaire de l’infection foetale à cytomégalovirus par l’administration de valaciclovir dans les primo-infections maternelles périconceptionnelles et du premier trimestre de la grossesse

Christos Chatzakis, Nicolas Bourgon, Marianne Leruez-Ville, Y. Ville

fr (code pays fourni par la source)

First real-world study of fetal therapy with CFTR modulators in cystic fibrosis: Report from the MODUL-CF study

Anne-Marie Bonnel, Tiphaine Bihouée, Mélanie Ribault, Marine Driessen et autres

fr (code pays fourni par la source)

Fetal Urinoma Secondary to Posterior Urethral Valve and Its Association to Postnatal Renal Function: A Multicenter Retrospective Study

Flore‐Anne Martin, Matthieu Peycelon, Nicolas Vinit, Thibault Planchamp et autres

AIM: The role of prenatal urinoma in lower urinary tract obstruction (LUTO) such as posterior urethral valves (PUV) is debated. We aimed to describe the risk factors associated with fetal urinoma and the association between fetal urinoma and postnatal renal function before …

fr (code pays fourni par la source)

Quantification of maternal and fetal valaciclovir exposure in a pharmacokinetic study of cytomegalovirus-infected pregnant women treated to prevent vertical transmission

Valentine Faure‐Bardon, Naïm Bouazza, Sihem Benaboud, Frantz Foissac et autres

BACKGROUND: In cases of maternal primary infection with cytomegalovirus (CMV-MPI) maternal treatment with oral valaciclovir 8 g/day has been shown to reduce the risk of fetal infection. The pharmacological profile of this high dosage during pregnancy is not yet known. OBJECTIVES: To …

fr, us (code pays fourni par la source)

Foetal achondroplasia: Prenatal diagnosis, outcome and perspectives

D. Grévent, Bettina Bessières, Laurent Julien Salomon, Laurence Legeai‐Mallet et autres

fr (code pays fourni par la source)

The Effect of Valacyclovir on Secondary Prevention of Congenital Cytomegalovirus Infection, Following Primary Maternal Infection Acquired Periconceptionally or in the First Trimester of Pregnancy: An Individual Patient Data Meta-analysis

Christos Chatzakis, Karen Shahar-Nissan, Valentine Faure‐Bardon, Olivier Picone et autres

(Abstracted from Am J Obstet Gynecol 2024;230(2):109–117 The incidence rate for congenital cytomegalovirus (cCMV) infection ranges from 0.2% to 2.2%. CMV is the most common cause of congenital hearing loss and accounts for about a third of cases.

Management of short cervix in twin-to-twin transfusion syndrome: a role for pessary placement following fetoscopic laser surgery?

Raphaël Bartin, Cleisson Fábio Andrioli Peralta, A. Horak, Karina Jorge Rodrigues da Costa et autres

fr, br (code pays fourni par la source)