2026
article
OpenAlex
Shisheng Chen, Yuanyuan Hu, Hongping Ge, Lin Fan et autres
Hypertrophic scar (HS) is a fibrotic disorder caused by imbalanced tissue repair after skin injury. Its core features include persistent inflammation and excessive collagen deposition. Current clinical treatments are limited by poor efficacy, severe local adverse reactions, and low transdermal delivery efficiency …
cn
(code pays fourni par la source)
2026
article
OpenAlex
Hongping Ge, S Chen, Chenle Dong, Tongyue Yang et autres
Hypertrophic scarring remains a challenging clinical problem because of its multifactorial pathology involving reduced apoptosis, excessive collagen deposition, aberrant fibroblast migration, and sustained inflammation. Here, we report Cuprorivaite as a multifunctional biomaterial for hypertrophic scar modulation with intrinsic photothermal enhancement. Through sustained …
cn, th
(code pays fourni par la source)
Accès ouvert
2025
article
OpenAlex
Hongping Ge, Jing Yu, Pan Li, Lifang Zhang et autres
A multifunctional adhesive electrospun BG/HPMC film delivers BG-derived bioactive ions (Si, Ca, Na, P) to the oral ulcer site, creating a biomimetic microenvironment. This enables synergistic antimicrobial, pro-proliferative (epithelial/endothelial), ROS-scavenging, and anti-inflammatory effects, accelerating ulcer re-epithelialization. The study demonstrates the effectiveness of …
cn
(code pays fourni par la source)
Accès ouvert
2024
article
OpenAlex
Zhaowenbin Zhang, Chen Fan, Q. N. Xu, Feng Guo et autres
Inspired by the scar-free wound healing in infants, an anti-scar strategy is proposed by accelerating wound healing using silicate bioactive materials. Bioglass/alginate composite hydrogels are applied, which significantly inhibit scar formation in rabbit ear scar models. The underlining mechanisms include stimulation of …
cn
(code pays fourni par la source)