Laurence Clément

Eltrombopag Added to Standard Immunosuppressive Treatment as Front‐Line Therapy for Severe Aplastic Anemia: Long‐Term Outcomes of the Phase‐3 Randomized Superiority EBMT ‐ SAAWP RACE Study

Antonio Maria Risitano, Simona Iacobelli, Austin Gladston Kulasekararaj, Marleen van Os et autres

The RACE study (NCT02009747) compared horse antithymocyte globulin (hATG) plus cyclosporine A (CsA) ± eltrombopag as initial immunosuppressive treatment (IST) for severe aplastic anemia. Here we report the final 2-year analysis of this prospective randomized phase III study. One hundred ninety-seven treatment-naive …

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Relapsed Philadelphia chromosome‐positive B‐cell acute lymphoblastic leukaemia responds well to a combination of modified hyper‐CVAD, blinatumomab and tyrosine kinase inhibitor

Gaétan Basile, Jean Galtier, Titouan Cazaubiel, Édouard Forcade et autres

Introduction: Adults with relapsed or refractory Philadelphia chromosome-positive B-cell precursor acute lymphoblastic leukaemia (R/R Ph+ BCP-ALL) have a dismal outcome. Blinatumomab as a single agent has shown activity in R/R Ph- BCP-ALL, and second or third-generation tyrosine kinase inhibitors (TKIs) can produce …

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Devenir des lymphomes T cutanés après allogreffe de cellules souches hématopoïétiques

V. Rosette, Anne Pham‐Ledard, E. Forcade, Laurence Clément et autres

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Eltrombopag Added to Standard Immunosuppressive Treatment Improves Long-Term Outcomes As Front-Line Therapy for Severe Aplastic Anemia: Final 2-Year Analysis of EBMT-Saawp Race Study

Antonio Maria Risitano, Simona Iacobelli, Austin Gladston Kulasekararaj, Marleen van Os et autres

Introduction The RACE study (NCT02009747) compared standard Immuno-Suppressive Treatment (IST) (as horse antithymocyte globulin plus ciclosporin A) ± eltrombopag [EPAG] as front-line treatment for Severe Aplastic Anemia (SAA). Primary analysis has shown that triple therapy improved rate and quality of hematological response, …

nl, it, gb, fr, es, ch (code pays fourni par la source)

A-232 Outcome of cutaneous T-cell lymphomas after allogeneic hematopoietic stem cell transplantation : focus on relapses and their management

V. Rosette, Anne Pham‐Ledard, E. Forcade, Laurence Clément et autres

Impact of the number of organs retrieved during multiple organ procurement on short and long term renal graft function

T. Ghestem, Markus Uhl, F. Taha, Kévin Kaulanjan et autres

On behalf of the SFGM‐TC: Real‐life use of third‐party virus‐specific T‐cell transfer in immunocompromised transplanted patients

Esther Hazane Leroyer, Nadine Petitpain, Stéphane Morisset, Bénédicte Neven et autres

^Maud D'Aveni and Danièle Bensoussan contributed equally to the

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Reduced-toxicity myeloablative conditioning regimen using fludarabine and full doses of intravenous busulfan in pediatric patients not eligible for standard myeloablative conditioning regimens: Results of a multicenter prospective phase 2 trial

Fanny Rialland, Audrey Grain, Myriam Labopin, Gérard P. F. Michel et autres

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VANDA regimen followed by blinatumomab leads to favourable outcome in patients with Philadelphia chromosome‐negative B‐precursor acute lymphoblastic leukaemia in first relapse

Luc Héraudet, Jean Galtier, Simon Favre, Florent Peyraud et autres

Adults with relapsed or refractory B-precursor acute lymphoblastic leukaemia (R/R BCP-ALL) have very poor outcome. Blinatumomab as single agent has shown activity in R/R BCP-ALL. We aimed to assess the activity of blinatumomab in concomitant association with intensive chemotherapy. Seventeen patients with …

Eltrombopag Added to Immunosuppression in Severe Aplastic Anemia

Régis Peffault de Latour, Austin Gladston Kulasekararaj, Simona Iacobelli, Sofie Rosanne Terwel et autres

BACKGROUND: A single-group, phase 1-2 study indicated that eltrombopag improved the efficacy of standard immunosuppressive therapy that entailed horse antithymocyte globulin (ATG) plus cyclosporine in patients with severe aplastic anemia. METHODS: In this prospective, investigator-led, open-label, multicenter, randomized, phase 3 trial, we …

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AMAHRELIS : ADCETRIS MAINTENANCE AFTER AUTOLOGOUS STEM CELL TRANSPLANTATION IN HODGKIN LYMPHOMA : A REAL LIFE STUDY FROM SFGMTC AND LYSA GROUPS

Amira Marouf, Anne‐Ségolène Cottereau, Salim Kanoun, Paul Deschamps et autres

ASCT.This analysis was performed after one-to-one propensity score matching generated 24 pairs with well-balanced baseline confounding factors and with an adjustment on the propensity score on the whole population, and showed a similar outcome on PFS, whereas BV maintenance offers a better …

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Adoptive immunotherapy of refractory viral infections after allogeneic HSCT: An academic network framing the use of ATMP under hospital exemption

Yingying Wang, Marcelo De Carvalho Bittencourt, Typhaine Pierre, Mélanie Gauthier et autres