Clara Villanueva

Desarrollo Académico y Profesional en el Área de la Salud con Uso de IA

Aldo Alexi Acosta Linares, Clara Villanueva

El estudio evalúa el impacto de la inteligencia artificial (IA) en la formación académica y el desarrollo profesional en salud, abarcando educación médica y práctica clínica entre 2020–2024. Su alcance consideró investigaciones indexadas en bases como Scopus y Web of Science. Metodológicamente …

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Heterogeneity of cognitive progression and clinical predictors in Parkinson’s disease–subjective cognitive decline

Saül Martínez‐Horta, Arnau Puig‐Davi, Andrea Horta‐Barba, Javier Pagonabarraga et autres

Abstract Background Parkinson’s Disease (PD)-associated subjective cognitive decline (PDSCD) is defined as cognitive complaints without objective cognitive impairment. Based on most studies, it is associated with a greater risk of cognitive decline and may represent a prodromal stage of cognitive impairment. Methods …

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Dysphagia in Parkinson´s disease. A 5-year follow-up study

Diego Santos‐García, Teresa de Deus Fonticoba, Silvia Jesús, Marina Cosgaya et autres

BACKGROUND AND OBJECTIVE: Dysphagia at time of diagnosis suggests atypical parkinsonism instead Parkinson´s disease (PD). Our aim was to analyze the frequency of dysphagia in patients with early PD comparing with a control group and to identify related factors. PATIENTS AND METHODS: …

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Cognitive impairment and dementia in young onset Parkinson’s disease

Diego Santos‐García, Teresa de Deus Fonticoba, Carlos Cores Bartolomé, María J. Feal Painceiras et autres

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Predictors of clinically significant quality of life impairment in Parkinson’s disease

Diego Santos‐García, Teresa de Deus Fonticoba, Carlos Cores, Guillermo Muñoz et autres

Abstract Quality of life (QOL) plays an important role in independent living in Parkinson’s disease (PD) patients, being crucial to know what factors impact QoL throughout the course of the disease. Here we identified predictors of QoL impairment in PD patients from …

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Non-motor symptom burden in patients with Parkinson’s disease with impulse control disorders and compulsive behaviours: results from the COPPADIS cohort

Silvia Jesús, Miguel A. Labrador‐Espinosa, A. D. Adarmes, Carmen Barrio et autres

The study was aimed at analysing the frequency of impulse control disorders (ICDs) and compulsive behaviours (CBs) in patients with Parkinson's disease (PD) and in control subjects (CS) as well as the relationship between ICDs/CBs and motor, nonmotor features and dopaminergic treatment …

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Non‐motor symptom burden is strongly correlated to motor complications in patients with Parkinson’s disease

Diego Santos‐García, T. de Deus Fonticoba, E. Suárez Castro, Darrian McAfee et autres

BACKGROUND AND PURPOSE: The objective of this study was to analyze the relationship between motor complications and non-motor symptom (NMS) burden in a population of patients with Parkinson's disease (PD) and also in a subgroup of patients with early PD. METHODS: Patients …

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Non-motor symptoms burden, mood, and gait problems are the most significant factors contributing to a poor quality of life in non-demented Parkinson's disease patients: Results from the COPPADIS Study Cohort

Diego Santos‐García, T. de Deus Fonticoba, E. Suárez Castro, Carmen Borrué et autres

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Simultaneous Stimulation of the Globus Pallidus Interna and the Nucleus Basalis of Meynert in the Parkinson-Dementia Syndrome

Cristina Nombela, Andrés M. Lozano, Clara Villanueva, Juan A. Barcia

BACKGROUND/AIM: The prevalence of cognitive symptoms in recently diagnosed Parkinson's disease (PD) patients may be as high as 60%. We report a novel deep brain stimulation (DBS) strategy targeting both motor and cognitive symptoms. METHODS: A PD patient diagnosed with mild cognitive …

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Stimulation of the Tractography-Defined Subthalamic Nucleus Regions Correlates With Clinical Outcomes

Josué M. Avecillas-Chasín, Fernando Alonso‐Frech, Cristina Nombela, Clara Villanueva et autres

BACKGROUND: Although deep brain stimulation (DBS) of the dorsolateral subthalamic nucleus (STN) is a well-established surgical treatment for patients with Parkinson disease (PD), there is still controversy about the relationship between the functional segregation of the STN and clinical outcomes. OBJECTIVE: To …

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Reduced Cancer Incidence in Huntington’s Disease: Analysis in the Registry Study

Paul McNulty, Richard Pilcher, Renata Necuiniate, Alis Hughes et autres

BACKGROUND: People with Huntington's disease (HD) have been observed to have lower rates of cancers. OBJECTIVE: To investigate the relationship between age of onset of HD, CAG repeat length, and cancer diagnosis. METHODS: Data were obtained from the European Huntington's disease network …

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Identification of genetic variants associated with Huntington's disease progression: a genome-wide association study

Davina J. Hensman Moss, Antonio F. Pardiñas, Douglas R. Langbehn, Kitty Lo et autres

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