José Remacle

Data from ABCA3 as a Possible Cause of Drug Resistance in Childhood Acute Myeloid Leukemia

Daniel Steinbach, Jean‐Pierre Gillet, Axel Sauerbrey, Bernd Gruhn et autres

Abstract Background: A major issue in the treatment of acute myeloid leukemia (AML) is resistance to chemotherapeutic drugs. Multidrug resistance can be caused by ATP-binding cassette (ABC) transporters that function as drug efflux pumps. The majority of these proteins have not yet …

de, be (code pays fourni par la source)

Data from ABCA3 as a Possible Cause of Drug Resistance in Childhood Acute Myeloid Leukemia

Daniel Steinbach, Jean‐Pierre Gillet, Axel Sauerbrey, Bernd Gruhn et autres

Abstract Background: A major issue in the treatment of acute myeloid leukemia (AML) is resistance to chemotherapeutic drugs. Multidrug resistance can be caused by ATP-binding cassette (ABC) transporters that function as drug efflux pumps. The majority of these proteins have not yet …

Supplementary Figures 1-2 from ABCA3 as a Possible Cause of Drug Resistance in Childhood Acute Myeloid Leukemia

Daniel Steinbach, Jean‐Pierre Gillet, Axel Sauerbrey, Bernd Gruhn et autres

Supplementary Figures 1-2 from ABCA3 as a Possible Cause of Drug Resistance in Childhood Acute Myeloid Leukemia

Supplementary Figures 1-2 from ABCA3 as a Possible Cause of Drug Resistance in Childhood Acute Myeloid Leukemia

Daniel Steinbach, Jean‐Pierre Gillet, Axel Sauerbrey, Bernd Gruhn et autres

Supplementary Figures 1-2 from ABCA3 as a Possible Cause of Drug Resistance in Childhood Acute Myeloid Leukemia

Subcellular Localization of Glutathione Peroxidase, Change in Glutathione System during Ageing and Effects on Cardiometabolic Risks and Associated Diseases

Théophile Mbemba Fundu, Paulin Mutwale Kapepula, Justin Mboloko Esimo, José Remacle et autres

Glutathione peroxidase (GPx) is a selenoprotein with biological properties that allow the detoxification of endogenous or exogenous reactive oxygen species as well as the elimination of xenobiotic compounds in the cells.Due to its isoform activities and pathophysiological functions, GPx holds the status …

République démocratique du Congo, be (code pays fourni par la source)

Examination of the role of integrin β3 in chemoresistance by analysis of residual NACT tumor specimens and knock-in experiments

Madhumathy G Nair, Jyothi S. Prabhu, José Remacle, Sun P et autres

in (code pays fourni par la source)

Alternate Epigenetic Mechanism for the Repression of BRCA1 in Sporadic Breast Cancers Mediated by MIR182

Aruna Korlimarla, Jyothi S. Prabhu, José Remacle, Uthandaraman Mahalinga Raja et autres

in (code pays fourni par la source)

Design, recruitment, logistics, and data management of the GEHA (Genetics of Healthy Ageing) project

Axel Skytthe, Silvana Valensin, Bernard Jeune, Elisa Cevenini et autres

dk, it, fr, nl, ua, cn, pl, gb, de, be, gr, fi (code pays fourni par la source)

Comparative clinical and transcriptomal profiles of breast cancer between French and South Mediterranean patients show minor but significative biological differences.

Nasséra Chalabi, Dominique J Bernard-Gallon, Y. J. Bignon, F Kwiatkowski et autres

BACKGROUND: In Western countries, breast cancer incidence and mortality are higher than in Mediterranean countries. These differences have been ascribed to environmental factors but also to late-stage diagnostic and biological specific characteristics. PATIENTS AND METHODS: Between September 2002 and September 2005, we …

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Evaluation of a low density DNA microarray for small B-cell non-Hodgkin lymphoma differential diagnosis

Jean‐Pierre Gillet, Thierry Jo Molina, Jacques Jamart, Philippe Gaulard et autres

Lymphomas are classified according to the World Health Organisation (WHO) classification which defines subtypes on the basis of clinical, morphological, immunophenotypic, molecular and cytogenetic criteria. Differential diagnosis of the subtypes is sometimes difficult, especially for small B-cell lymphoma (SBCL). Standardisation of molecular …

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Bovine Serum-Albumin with Grafted RGD Tailed Cyclic Peptudes as an Engineered Proadhesive Protein

Janique Dewelle, Dominiqe Delforge, Sabine Pirotton, José Remacle et autres

be (code pays fourni par la source)

Hypoxia induces protection against etoposide-induced apoptosis: molecular profiling of changes in gene expression and transcription factor activity

Audrey Sermeus, Jean-Philippe Cosse, Marianne Crespin, Véronique Mainfroid et autres

BACKGROUND: it is now well established that hypoxia renders tumor cells resistant to radio- but also chemotherapy. However, few elements are currently available as for the mechanisms underlying this protection. RESULTS: in this study, physiological hypoxia was shown to inhibit apoptosis induced …

be (code pays fourni par la source)