Bruce H. Brundage

Survival in Patients with Primary Pulmonary Hypertension

Gilbert E. D’Alonzo, Robyn J. Barst, Stephen M. Ayres, Edward H. Bergofsky et autres

▪ Objective: To characterize mortality in persons diagnosed with primary pulmonary hypertension and to investigate factors associated with survival. ▪ Design: Registry with prospective follow-up. ▪...

Ultrafast Computed Tomography: A New Method for the Evaluation of Hypertrophic Cardiomyopathy

Eva V. Chomka, Christopher J. Wolfkiel, Stuart Rich, Jeffrey G. Shanes et autres

Hypertrophic cardiomyopathy (HCM) presents with a wide spectrum of heterogeneous morphology. Modalities used to assess HCM include echocardiography, cardiac catheterization, radionuclide angiography, conventional computed tomography (CT), and magnetic resonance imaging. This investigation was performed to assess the feasibility of using ultrafast CT …

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Tadalafil for the Treatment of Pulmonary Arterial Hypertension

Ronald J. Oudiz, Bruce H. Brundage, Nazzareno Galiè, Hossein Ardeschir Ghofrani et autres

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Tadalafil in idiopathic or heritable pulmonary arterial hypertension compared to pulmonary arterial hypertension associated with connective tissue disease

Nazzareno Galiè, Robyn J. Barst, Bruce H. Brundage, Hossein Ardeschir Ghofrani et autres

Patients (pts) with PAH associated with connective tissue disease (APAH-CTD) have a worse prognosis compared to idiopathic (I) or heritable (H)PAH. Our objective was to evaluate the clinical outcomes in these two subgroups. In a 16 week (wk), double-blind, placebo (PBO) controlled …

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Tadalafil monotherapy and as add-on to background bosentan in patients with pulmonary arterial hypertension

Robyn J. Barst, Ronald J. Oudiz, Anthony Beardsworth, Bruce H. Brundage et autres

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Don't Throw the Baby Out With the Bath Water

Bruce H. Brundage

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Tadalafil Therapy for Pulmonary Arterial Hypertension

Nazzareno Galiè, Bruce H. Brundage, Hossein Ardeschir Ghofrani, Ronald J. Oudiz et autres

BACKGROUND: Treatment options for pulmonary arterial hypertension target the prostacyclin, endothelin, or nitric oxide pathways. Tadalafil, a phosphodiesterase type-5 inhibitor, increases cGMP, the final mediator in the nitric oxide pathway. METHODS AND RESULTS: In this 16-week, double-blind, placebo-controlled study, 405 patients with …

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TADALAFIL IMPROVES EXERCISE CAPACITY, HEALTH RELATED QUALITY OF LIFE AND DELAYS TIME TO CLINICAL WORSENING IN PATIENTS WITH SYMPTOMATIC PULMONARY ARTERIAL HYPERTENSION (PAH)

Robyn J. Barst, Bruce H. Brundage, Hossein Ardeschir Ghofrani, Ronald J. Oudiz et autres

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ACCF/AHA 2007 Clinical Expert Consensus Document on Coronary Artery Calcium Scoring by Computed Tomography in Global Cardiovascular Risk Assessment and in Evaluation of Patients With Chest Pain

Philip Greenland, Robert O. Bonow, Bruce H. Brundage, Matthew Jay Budoff et autres

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ACCF/AHA 2007 Clinical Expert Consensus Document on Coronary Artery Calcium Scoring By Computed Tomography in Global Cardiovascular Risk Assessment and in Evaluation of Patients With Chest Pain

Philip Greenland, Robert O. Bonow, Bruce H. Brundage, Matthew Jay Budoff et autres

Working group 8: Defining the different types of cardiovascular specialists and developing a new model for training general clinical cardiologists

Valentı́n Fuster, John Winslow Hirshfeld, Alan S. Brown, Bruce H. Brundage et autres

Micrococcus-Associated Central Venous Catheter Infection in Patients With Pulmonary Arterial Hypertension

Ronald J. Oudiz, Allison C. Widlitz, Xiaosing J. Beckmann, Daisy Camanga et autres

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