Accès ouvert
2026
article
OpenAlex
Ki-Jun Ryu, Minju Kim, Jiyun Yoo
SNAI (snail family transcriptional repressor) is a master regulator of epithelial-mesenchymal transition (EMT), yet its protein abundance varies markedly across breast cancer subtypes and cellular states. We identify SNAI as a bona fide substrate of chaperone-mediated autophagy (CMA) and propose a localization …
kr
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Accès ouvert
2026
article
OpenAlex
Minju Kim, Keun-Seok Hong, Taeyoung Kim, Ki-Jun Ryu et autres
Snail (SNAI1), a central transcription factor driving epithelial-mesenchymal transition (EMT), is pivotal in cancer metastasis and tissue remodeling. Owing to its labile nature, Snail activity is tightly controlled by post-translational modifications that dictate its stability. Here this review summarizes how the ubiquitin-proteasome …
kr
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Accès ouvert
2026
article
OpenAlex
Semin Lee, Minjun Kim, Seungmin Lee, Hyo-Jin Kim et autres
Extracellular vesicles (EVs), including exosomes and microvesicles, act as transmitters of various biological signals through cell-cell communication. Although EVs derived from immune response cells have been partially studied, the characteristics of EVs mediated by NLR family pyrin domain-containing 3 (NLRP3) inflammasome activation …
kr, us
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Accès ouvert
2026
article
OpenAlex
Semin Lee, Minjun Kim, Seungmin Lee, Jiyun Yoo et autres
Objective: Cisplatin is a widely used chemotherapeutic agent due to its ability to damage DNA in the treatment of cancer. However, its clinical application is often limited by adverse effects on normal tissues, especially th... | Find, read and cite all the …
kr
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Accès ouvert
2013
article
OpenAlex
In-Kyu Kim, Young Chul Yun, Yong Chul Shin, Jiyun Yoo
꽃송이버섯(Sparassis crispa)은 항암 및 면역증강 효과가 뛰어나다고 알려져 있는 베타-글루칸의 함량이 건조중량의 40% 이상인 것으로 보고되고 있는 산림버섯이다. 일반적으로 버섯에서 추출한 베타-글루칸의 면역활성 및 항암 효과는 널리 알려져 있는 반면 꽃송이버섯 유래의 베타-글루칸에 의한 대식세포의 활성화 기작 및 자실체 추출물에 의한 항암 …
kr
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