T. Yano

[Non-Small Cell Lung Cancer in the Right Upper Lobe Was Surgically Resected, after Small Cell Lung Cancer of the Same Lobe with Complete Response to Chemoradiotherapy].

T. Yano, Jun Miyagi, Sakura Shimizu, Nobuyuki Shiroma et autres

A 60s man presented with leukemia for an underlying disease, which had CR to chemotherapy. By medical examination, an INSM1-positive small cell carcinoma was found next to the right lung hilar region. The patient was diagnosed with cT2aN1M0. Radiation therapy was performed …

jp (code pays fourni par la source)

ONOKORO project: Comprehensive research of cluster formation in medium-heavy and heavy nuclei

Y. Kubota, Kodjo Agbekponou, DeukSoon Ahn, H. Baba et autres

jp, kr (code pays fourni par la source)

PNS169 A STUDY ON THE FACTORS ASSOCIATED WITH HOSPITAL STAFFS INFLUENZA AT A UNIVERSITY HOSPITAL IN JAPAN

Yeongchang Jo, Hitoshi Hirose, T. Yano, Chiaki Sano et autres

jp (code pays fourni par la source)

Risk of rupture of unruptured cerebral aneurysms in elderly patients

Tomohito Hishikawa, Isao Date, Koji Tokunaga, Shinjiro Tominari et autres

OBJECTIVES: The aim of this study was to identify risk factors for rupture of unruptured cerebral aneurysms (UCAs) in elderly Japanese patients aged 70 years or older. METHODS: The participants included all patients 70 years of age or older in 3 prospective …

jp, us (code pays fourni par la source)

Role of multifunctional transcription factor TFII-I and putative tumour suppressor DBC1 in cell cycle and DNA double strand damage repair

Michihiro Tanikawa, Osamu Wada‐Hiraike, Naoko Yoshizawa-Sugata, A Shirane et autres

BACKGROUND: In multicellular organisms, precise control of cell cycle and the maintenance of genomic stability are crucial to prevent chromosomal alterations. The accurate function of the DNA damage pathway is maintained by DNA repair mechanisms including homologous recombination (HR). Herein, we show …

jp, us (code pays fourni par la source)

362 Anti-tumor Efficacy of DS-7423, a Novel PI3K/mTOR Dual Inhibitor, in Ovarian Clear Cell Adenocarcinoma

Tomoko Kashiyama, Koji Oda, Yoshiki Ikeda, Yoshinobu Shiose et autres

M313 A DIAGNOSTIC UTILITY OF SINGLE NUCLEOTIDE POLYMORPHISM ARRAYS IN SYNCHRONOUS CARCINOMAS

Yuji Ikeda, Katsutoshi Oda, Satoru Nakagawa, Osamu Hiraike et autres

Bone morphogenetic protein-7(BMP-7) might contribute to folliculogenesis by promoting angiogenesis

Ikumi Akiyama, Osamu Yoshino, Yutaka Osuga, T. Yano

jp (code pays fourni par la source)

SESSION 73: FEMALE FERTILITY PRESERVATION

Dror Meirow, Hila Raanani, Masha Brengauz, Jehoshua Dor et autres

Genotype-dependent efficacy of a dual PI3K/mTOR inhibitor, NVP-BEZ235, and an mTOR inhibitor, RAD001, in endometrial carcinomas.

Katsutoshi Oda, Keiko Shoji, Setsuko Nakagawa, Tomoko Kashiyama et autres

5110 Background: PI3K (phosphatidylinositol-3-kinase) /mTOR (mammalian target of rapamycin) pathway is frequently activated in endometrial cancer through various PI3K/AKT activating genetic alterations, including mutations in PTEN, PIK3CA, and K-Ras. We evaluated the activity of a dual PI3K/mTOR.inhibitor, NVP-BEZ235, and an mTOR inhibitor, …

jp (code pays fourni par la source)

TGF- 1 induces proteinase-activated receptor 2 (PAR2) expression in endometriotic stromal cells and stimulates PAR2 activation-induced secretion of IL-6

Atsushi Saito, Yutaka Osuga, Osamu Yoshino, M. Takamura et autres

BACKGROUND: Proteinase-activated receptor 2 (PAR2) is a G-protein-coupled receptor that is activated by several serine proteases. PAR2 activation in endometriotic stromal cells (ESCs) has been implicated in the development of endometriosis but the regulatory mechanism of PAR2 expression in ESC is unknown. …

jp (code pays fourni par la source)

Multifunctional transcription factor TFII-I is an activator of BRCA1 function

Michihiro Tanikawa, Osamu Wada‐Hiraike, Shunsuke Nakagawa, A Shirane et autres

BACKGROUND: The TFII-I is a multifunctional transcriptional factor known to bind specifically to several DNA sequence elements and to mediate growth factor signalling. A microdeletion at the chromosomal location 7q11.23 encoding TFII-I and the related family of transcription factors may result in …

jp (code pays fourni par la source)