Qianyu Zhang

Retraction Note: Zinc Deficiency Causes Glomerulosclerosis and Renal Interstitial Fibrosis Through Oxidative Stress and Increased Lactate Metabolism in Rats

Zixuan Huang, Yajie Liao, Yunxi Zheng, Ye Shang et autres

cn, gb (code pays fourni par la source)

The Effectiveness of Digital Intervention on Psychological Resilience in Postoperative Breast Cancer Patients During Chemotherapy Intervals: Quasi-Experimental Study

Xin He, Qianyu Zhang, Liping Wang, Qunying Fang et autres

Abstract Background Patients with breast cancer during postoperative chemotherapy intervals commonly experience psychological distress and reduced resilience while recovering at home. Digital mindfulness interventions may provide accessible psychological support during this vulnerable period; however, evidence regarding tailored interventions for postoperative patients with …

cn (code pays fourni par la source)

Skin-fold-inspired antimicrobial auxetic silk fibroin fabric for joint wound management

Qianyu Zhang, Qichang Dong, Mengru Wu, Zhijia Dong et autres

cn (code pays fourni par la source)

Diagnostic performance of mDIXON-Quant imaging in assessing glomerulosclerosis severity for chronic kidney disease: a comparative study of R2* and fat fraction parameters

Wenhui Wang, Renna Luo, Ye Ju, Q. Hu et autres

OBJECTIVE: To compare two region-of-interest (ROI) measurement methods based on mDIXON-Quant for distinguishing healthy volunteers (HV), chronic kidney disease (CKD) patients with low (≤ 15%) and high (> 15%) glomerulosclerosis (GS), and establish a non-invasive auxiliary protocol. METHODS: A total of 42 …

cn, ca (code pays fourni par la source)

Carrier-free nanoparticles derived from Huanglian Jiedu decoction target ATP5F1C to eliminate senescent cells and ameliorate pulmonary fibrosis

Ying Zhang, Lirun Zhou, Yajian Li, Weiling Wang et autres

cn (code pays fourni par la source)

Caffeic Acid Acts as a Potent Senomorphic and Alleviates Inflammation and Lung Fibrosis by Covalently Targeting Annexin A5 Protein in Mice

Yinhua Zhu, Ying Zhang, Qianyu Zhang, Ping Song et autres

The accumulation of senescent cells and their secretion of senescence-associated secretory phenotype (SASP) play important roles in the pathogenesis of idiopathic pulmonary fibrosis (IPF). Small molecules, known as senolytics or senomorphics, have been effective in targeting senescent cells. Although senolytic drugs have …

cn, sg (code pays fourni par la source)

Theoretical Origin and Application of the Method of Promoting Blood Circulation to Prevent Miscarriage in Recurrent Spontaneous Abortion Induced by Blood Stasis

Qianyu Zhang, Xinchun Xiao

Recurrent spontaneous abortion (RSA) represents a significant reproductive health challenge affecting women of childbearing age, characterized by complex etiology and pathogenesis. In Traditional Chinese Medicine (TCM), RSA falls under the categories of “habitual abortion” and “recurrent miscarriage.” Beyond traditional pathological mechanisms such …

Decoupling Half‐Process Assisted Mitochondrial Transplantation via Self‐Stripping pHLIP Boosts Macrophages Reprogramming for Inflammation Resolution

Ping He, Xianghao Wu, Mingzheng Li, Kehao Liu et autres

Exogenous mitochondrial transplantation holds promise for reprogramming macrophages with mitochondrial dysfunction to alleviate inflammation, yet its efficacy is hindered by poor targeting, low efficiency, or functional interference and cytotoxicity of modifiers. Herein, a convenient pH-low insertion peptides (pHLIPs)-tailored mitochondrial "decoupling transplantation" strategy …

cn (code pays fourni par la source)

Long-Acting Copper Ion Hydrogel for Immune Regulation in Diabetic Wounds

Ziyu Huang, Xiaoke Su, Xianghao Wu, Qianyu Zhang et autres

Dysregulated copper ion homeostasis is a key factor in disrupting the immune microenvironment of diabetic wounds. However, conventional copper delivery systems are limited by unstable release kinetics and transient therapeutic effects. To address these challenges, this study introduces a long-acting copper ion-releasing …

cn (code pays fourni par la source)

Targeting fibroblasts in pathological bone formation: mechanisms and treatments

Qianyu Zhang, Zhouxiang Li, Xinyi Wu, Yuxiong Chen et autres

Fibroblasts are integral to the pathological processes underlying abnormal bone formation, including heterotopic ossification (HO), ankylosing spondylitis (AS), and ossification of the posterior longitudinal ligament (OPLL). This review summarized the diverse roles of fibroblasts, from their transdifferentiation into osteoblast-like cells to their …

cn (code pays fourni par la source)

Neoadjuvant Chemotherapy With Cisplatin Up‐Regulates GSDMD to Enhance Oral Squamous Cell Carcinoma Metastasis Through MMP14‐Mediated EMT Activation

Zixian Huang, Qiming Jiang, Qianyu Zhang, Rui Chen et autres

Neoadjuvant chemotherapy has been widely used for the treatment of solid tumors. However, clinical observations have shown that patients with oral squamous cell carcinoma (OSCC) who are receiving neoadjuvant chemotherapy with cisplatin still face issues such as a poor lymph node response …

cn (code pays fourni par la source)

Analysis of factors influencing of supportive care needs in chemotherapy interval breast cancer patients based on a structural equation model: a cross-sectional study

Wei Chao Liu, Liping Wang, Chengang Hong, Qianyu Zhang et autres

In recent years, although there have been studies on the supportive care needs (SCNs) of breast cancer patients, there have been no studies on the factors affecting the supportive care needs of breast cancer patients during the chemotherapy interval. Guided by the …

cn (code pays fourni par la source)