Raman Kumar

Novel PCDH12 pathogenic missense variants cause neurodevelopmental disorders with ocular malformation

Jennifer Rakotomamonjy, Lucas Fares-Taie, Raman Kumar, Cole Gebert et autres

Abstract Protocadherin-12 (PCDH12), a cell-adhesion protein belonging to the non-clustered protocadherin family, plays a crucial role in the establishment and regulation of neuronal connections and communication. Bi-allelic loss-of-function (LoF) variants in the PCDH12 gene have been associated with several neurodevelopmental disorders (NDDs) …

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Synergistic reinforcement of HPAM/Cr(III) acetate polymer gels using Fe₃O₄@Saponin/Ni nanocomposites for conformance control applications

Heyder Mhohamdi, Raman Kumar, Ashutosh Pattanaik, Hrushikesh Sarangi et autres

The persistent challenge of gel instability and inadequate performance under harsh reservoir conditions limits the efficiency of polymer-based systems in enhanced oil recovery (EOR) and water shutoff operations. This study addresses these limitations by introducing Fe₃O₄@Saponin/Ni nanocomposites as synergistic reinforcing agents within …

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P0276 As severe as Acute Severe Ulcerative Colitis (ASUC)? Clinical findings from a large cohort of moderately severe acute Ulcerative Colitis inpatients

Amirah Etchegaray, Naeman Goetz, K Hannigan, Jennifer Phillips et autres

Abstract Background The Truelove and Witts criteria (TWC) has historically guided clinical decision-making for the disposition of acute Ulcerative Colitis (UC) patients.1 However, many TWC moderately severe (MSUC) patients also require inpatient management for intravenous corticosteroids (IVCS). We aimed to explore the …

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P0776 The Likelihood of Early Infliximab Failure (LEIF) Score for Day Two Prediction of Infliximab Failure in Acute Ulcerative Colitis

Naeman Goetz, Amirah Etchegaray, George Tambakis, J Phillips et autres

Abstract Background Infliximab (IFX) is the primary rescue therapy for steroid-refractory acute ulcerative colitis (UC), but up to 40% of patients do not respond. The Medical Rescue Therapy (MRT) score is one of the few tools available to predict early IFX response, …

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P0339 Unmasking the faces of Severe Colitis: A data-driven approach to defining Ulcerative Colitis phenotypes and predicting clinical outcomes

Amirah Etchegaray, Naeman Goetz, Satomi Okano, Günter Härtel et autres

Abstract Background The clinical heterogeneity of acute Ulcerative Colitis (UC) poses a notable challenge to effective risk stratification and timely intervention. Existing severity indices derived in the 20th century may be obfuscated by the effects of novel therapeutics and fail to capture …

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P1236 Incidence and prevalence of complicated inflammatory bowel disease in Queensland, Australia: a population-based data linkage study

George Tambakis, Satomi Okano, Günter Härtel, Raman Kumar et autres

Abstract Background Inflammatory bowel disease (IBD), including ulcerative colitis (UC), Crohn’s disease (CD) represents a spectrum of chronic inflammatory conditions affecting the gastrointestinal tract. Whilst some patients experience a benign disease course, others develop complicated IBD characterised by frequent hospitalisations and surgery. …

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Strengthening colonoscopy screening in primary care: A preventive imperative before the coming surge

Manas Pustake, Raman Kumar

India stands at a critical juncture in its cancer control efforts. While cervical, breast, and oral cancers receive substantial screening attention, colorectal cancer (CRC), a largely preventable disease, remains conspicuously absent from the national preventive health agenda. With approximately 70,000 new cases …

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Effectiveness of suspending agents and determination of optimal conditions for crude oil demulsification in oil refining

Hongli Wang, Farag M. A. Altalbawy, Hussein Basim Furaijl, Nareshkumar Jadeja et autres

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Predicting filter cake thickness in drilling fluids using machine learning techniques

Minghui OU, Mohammed Al-Bahra, Raman Kumar, Ashutosh Pattanaik et autres

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Author response for "Influence of Structural Diversity in Co(II)-oxamide Complexes Towards Single Molecule Magnets and Electrochemical Oxygen Evolution Reaction †"

Swati Nag, Raman Kumar, Manjeet Singh, Atanu Panda et autres

Author response for "Influence of Structural Diversity in Co(II)-oxamide Complexes Towards Single Molecule Magnets and Electrochemical Oxygen Evolution Reaction †"

Swati Nag, Raman Kumar, Manjeet Singh, Atanu Panda et autres

Author response for "Influence of Structural Diversity in Co(II)-oxamide Complexes Towards Single Molecule Magnets and Electrochemical Oxygen Evolution Reaction †"

Swati Nag, Raman Kumar, Manjeet Singh, Atanu Panda et autres