Accès ouvert
2026
article
OpenAlex
Soner Kumcu, Eren Oral Kalbisağde, Burak Toprak
Background: Despite advances in surgical and perioperative care, early mortality and postoperative complications after isolated coronary artery bypass grafting (CABG) remain clinically relevant. Conventional risk models primarily reflect baseline clinical and operative characteristics and may not fully capture the dynamic immune-inflammatory response …
tr
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Accès ouvert
2026
article
OpenAlex
Özkan Karaca, Burak Toprak, Nihat Söylemez, Mustafa Ekici et autres
Background Permanent pacemaker implantation (PPI) and early mortality remain important complications after transcatheter aortic valve implantation (TAVI). The Hematological Inflammatory Global Score (HIGS), derived from routine hematological parameters, may provide prognostic information after TAVI. This study evaluated the association of HIGS with …
tr, is
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Accès ouvert
2026
article
OpenAlex
Burak Toprak, Abdülkadir Bilgiç, Rahime Akın, Mustafa Ekici et autres
Background: Systemic inflammation plays a central role in determining postoperative outcomes in patients undergoing isolated coronary artery bypass grafting with cardiopulmonary bypass. Traditional inflammatory indices such as the neutrophil-to-lymphocyte ratio and the platelet-to-lymphocyte ratio have prognostic value; however, their dynamic behavior during …
tr
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Accès ouvert
2026
article
OpenAlex
Burak Toprak, Nihat Söylemez, Menaf Akın Sert, Özkan Karaca et autres
Background: Coronary anatomical complexity is commonly used for perioperative risk assessment in patients undergoing coronary artery bypass grafting (CABG), although it may not fully reflect systemic biological vulnerability. This study aimed to evaluate the association between the Prognostic Nutritional Index (PNI), a …
tr
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Accès ouvert
2026
article
OpenAlex
Özkan Karaca, Burak Toprak, Mustafa Ekici, Nihat Söylemez et autres
Background: Inflammation plays a central role in the pathophysiology and clinical progression of acute myocardial infarction (MI). Although clopidogrel is known to exert potential anti-inflammatory effects in addition to platelet inhibition, the behavior of the early inflammatory response after treatment initiation and …
tr
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Accès ouvert
2026
article
OpenAlex
Rıdvan Bora, Burak Toprak, Emrah Yeşil, Rojda Tanrıverdi et autres
Background: Inflammation plays a central role in the pathophysiology of acute coronary syndrome (ACS). Raftlin, a lipid raft-associated inflammatory protein involved in immune signaling, has emerged as a potential biomarker in cardiovascular disease. This study aimed to evaluate circulating raftlin levels and …
tr, us, gb
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Accès ouvert
2026
article
OpenAlex
Nihat Söylemez, Burak Toprak, Özkan Karaca, Samet Yılmaz et autres
Background: Heart failure (HF) remains a major early complication following myocardial infarction (MI), contributing significantly to morbidity and adverse clinical outcomes. Reliable early risk stratification is essential for optimizing post-MI management. This study aimed to evaluate the prognostic performance and incremental value …
tr
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Accès ouvert
2026
article
OpenAlex
Samet Yımaz, Nihat Söylemez, Mustafa Ekici, Mahmut Yılmaz et autres
Background: The C-reactive protein-to-albumin ratio (CAR) has emerged as a composite biomarker reflecting both systemic inflammation and nutritional status. This study investigated the prognostic value of preoperative and postoperative CAR in predicting early mortality following coronary artery bypass grafting (CABG). Methods: This …
tr
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Accès ouvert
2026
article
OpenAlex
Rıdvan Bora, Rojda Tanrıverdi, Şenay Balci Fidancı, Burak Toprak et autres
Background/Objectives: Coronary artery disease is a chronic inflammatory disorder characterized by progressive atherosclerosis and heterogeneous clinical presentations ranging from acute coronary events to stable ischemic conditions. Galectin-3 is a β-galactoside-binding lectin involved in inflammatory responses, fibrosis, and tissue remodeling, and has been …
tr
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2026
article
OpenAlex
Rıdvan Bora, Rojda Tanrıverdi, Şenay Balcı, Cemil Gülüm et autres
BACKGROUND: Coronary artery disease (CAD) is a multifactorial disorder influenced by both environmental and genetic factors. The PLAU gene, which plays a key role in fibrinolysis, inflammation, and extracellular matrix remodeling, has been implicated in atherosclerotic plaque progression. However, the relationship between …
tr
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Accès ouvert
2026
article
OpenAlex
Hakan Eke, Burak Toprak, Elif Dilber Bozkurt
Laryngoscopy and intubation provoke strong sympathetic activation and may cause hemodynamic instability in cardiovascular surgery patients. Maintaining adequate hypnotic depth and cerebral oxygenation during induction is essential. Although BIS and NIRS are widely used, their simultaneous behavior during induction in a homogeneous …
tr
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Accès ouvert
2026
article
OpenAlex
Muhammed Adıyaman, Rıdvan Bora, Burak Toprak, Mustafa Demir et autres
Background: Contrast-induced nephropathy (CIN) is a common complication after coronary angiography (CAG), especially in patients with diabetes. Sodium–glucose cotransporter-2 (SGLT-2) inhibitors are well known for their cardio–renal protective effects, but their impact on CIN remains unclear. This study aimed to evaluate the …
us, tr, gb
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