Accès ouvert
2026
article
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Yifan Zhang, Xiaomin Xu, Shulin Wang, Xiaochen Yin et autres
BACKGROUND: The discovery and therapeutic application of immune checkpoint inhibitors (ICIs) have significantly improved clinical outcomes in cancer treatment. However, the response rate is still low in gastrointestinal (GI) cancers. The gut microbiome's impact on immune modulation is a promising area for …
cn, il
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Accès ouvert
2026
article
OpenAlex
Jie Zhao, Jiacheng Hao, Jincheng Chen, Mengze Lyu et autres
Oral tolerance represents a hallmark of intestinal mucosal immunity to prevent inflammatory responses to harmless natural antigens, such as dietary components or commensal organisms. According to recent studies, RORγt+ antigen-presenting cell (APC) contributes to intestinal homeostasis, including oral tolerance, through inducing microbiota- …
cn, us
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2026
article
OpenAlex
Na Li, X. Guo
Colonization resistance is a fundamental host defense mechanism that relies on the synergistic interaction between the gut microbiota and the host immune system to prevent enteric pathogen colonization and infection. This review synthesizes current knowledge of the multifaceted mechanisms governing colonization resistance …
cn
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Accès ouvert
2017
erratum
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B. P. Abbott, R. Abbott, T. D. Abbott, M. R. Abernathy et autres
International audience
us, it, fr, de, nl, br, in, au, gb, hu, pl, ru
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