Jean-François Gauchat

A novel modulator of IL-6R prevents inflammation-induced preterm birth and improves newborn outcome

France Côté, Élizabeth Prairie, Estefania Marin Sierra, Christiane Quiniou et autres

Preterm birth (PTB) is a major cause of neonatal mortality and morbidity. Evidence supports a determinant role for interleukin-6 (IL-6) in the pathophysiology of PTB. Our group developed a small peptide, HSJ633, that antagonizes the interleukin-6 receptor (IL-6R). Binding assays performed on …

ca, au (code pays fourni par la source)

Thiols Decrease Human IL-4 Production and IL-4-lnduced Immunoglobulin Synthesis

Pascale Jeannin, Yves Delneste, Jean‐Pierre Aubry, Sybille Lecoanet-Henchoz et autres

ch, us (code pays fourni par la source)

Subject Index, Vol. 113, No.1–3, 1997

Johannes Ring, Fritz Melchers, Stephen Joseph Galli, Alain L. de Weck et autres

Contents, Vol. 107, No. 1-3, 1995

Stephen T. Holgate, Martin K. Church, Peter Hugo Howarth, Newton E. Morton et autres

Author Index, Vol. 113, No. 1–3, 1997

Johannes Ring, Fritz Melchers, Stephen Joseph Galli, Alain L. de Weck et autres

CLF associates with CLC to form a functional heteromeric ligand for the CNTF receptor complex

Greg Elson, Eric Lelièvre, Catherine Guillet, Sylvie Chevalier et autres

fr (code pays fourni par la source)

The distribution of IL-13 receptor α1 expression on B cells, T cells and monocytes and its regulation by IL-13 and IL-4

Pierre Graber, Denise Gretener, Suzanne Herren, Jean-Pierre Aubry et autres

To study the expression of IL-13 receptor alpha1 (IL-13Ralpha1), specific monoclonal antibodies (mAb) were generated. Surface expression of the IL-13Ralpha1 on B cells, monocytes and T cells was assessed by flow cytometry using these specific mAb. Among tonsillar B cells, the expression …

Alpha-1 antitrypsin up-regulates human B cell differentiation selectively into IgE- and IgG4-secreting cells

Pascale Jeannin, Sybille Lecoanet-Henchoz, Yves Delneste, Jean-François Gauchat et autres

Numerous allergens have proteolytic activities. It has been speculated that this property may contribute to their allergenicity. Therefore, we have evaluated the effect of different physiological protease inhibitors (PI) on the regulation of human IgE synthesis. Unexpectedly, the serine PI, alpha-1 antitrypsin, …

Induction of human IgE synthesis in B cells by mast cells and basophils

Jean-François Gauchat, Sybille Henchoz, Gonzalo J. Mazzei, Jean‐Pierre Aubry et autres

ch, gb, jp, us (code pays fourni par la source)