Kulranjan Singh

Clinicopathological and Prognostic Implications of Circulating MicroRNA-429 in Breast Cancer Patients

Shivangini Sharma, Taniya Suryavanshi, Preeti Agarwal, Alok Singh et autres

BACKGROUND/AIMS: MicroRNA-429 (miR-429), a member of the miR-200 family, has been implicated in epithelial-mesenchymal transition and tumor progression, yet its clinicopathological significance in breast cancer remains unclear. This study aimed to evaluate serum miR-429 expression in treatment-naïve breast cancer patients and correlate …

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Impact of the tumor microenvironment on survival in anaplastic thyroid carcinoma

Chanchal Rana, Prabhakar Mishra, Kulranjan Singh, Pooja Ramakant et autres

Anaplastic thyroid carcinoma (ATC) is a highly aggressive malignancy characterized by nearly 100% mortality and significant therapeutic challenges. This study investigated the tumour microenvironment (TME) in ATC, focusing on immune checkpoint molecules (PD-L1/PD-1), tumour-associated macrophages (TAMs), and E-cadherin expression. A retrospective cohort …

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Exploring the Tumor Microenvironment of Anaplastic Thyroid Carcinoma and its impact on Patient Survival

Chanchal Rana, Prabhakar Mishra, Kulranjan Singh, Pooja Ramakant et autres

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Effect of Erector Spinae Block and Pectoralis Block on Quality of Recovery and Analgesia After Modified Radical Mastectomy

Md Hammad Mohsin, Reetu Verma, Dinesh Kumar Singh, Sarita Singh et autres

Objectives: Post-operative pain after a modified radical mastectomy ranges from moderate to severe. Pectoralis (PECS) block has been found to be more effective than erector spinae block in reducing pain and the consumption of rescue analgesia in the post-operative period. This study …

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Cellular fibroadenoma versus phyllodes tumors: A pre‐operative diagnostic approach based on radiological and cytological features

Chanchal Rana, Nidhi Kamal, Prabhakar Mishra, Akanksha Singh et autres

OBJECTIVE: This study has been designed in an effort to identify the clinico-radiological and cytological features that could effectively help in differentiating cellular fibroadenoma (CFA) and phyllodes tumors (PT), which have several overlapping characteristics. METHOD: Histologically proven cases of CFA and PT …

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Osteoclastic variant of anaplastic thyroid carcinoma: An insight into a rarest of rare entity

Poorvi Mathur, Chanchal Rana, Vaibhav Sheel Gupta, Pooja Ramakant et autres

Anaplastic thyroid carcinoma is a rare and a very aggressive thyroid malignancy with a dismal prognosis. It has a short history and presents with a rapidly increasing neck mass associated with compressive symptoms like pain, hoarseness of voice, dysphagia and shortness of …

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Letter to the Editor: Development of a Rapid Intraoperative Point‐of‐Care Method Using Tissue Suspension to Differentiate Parathyroid Tissue: A Possible Substitute for Frozen Sections

Upander Kumar, Pooja Ramakant, Kulranjan Singh, Anand B. Kumar et autres

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Effect of the Noninvasive Follicular Thyroid Neoplasm With Papillary-Like Nuclear Features (NIFTP) Nomenclature Revision on Indian Thyroid Fine-Needle Aspiration Practice

Chanchal Rana, Pooja Ramakant, Divya Goel, Akanksha Singh et autres

OBJECTIVES: To analyze risk of malignancy (ROM) in Bethesda categories (BCs) and the impact of noninvasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP) reclassification on malignancy risk and surgical outcome. METHODS: In this retrospective study based on fine-needle aspiration samples with …

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Noninvasive follicular neoplasm with papillary like nuclear features: A comprehensive analysis with a diagnostic algorithm

Chanchal Rana, Shreyamsa Manjunath, Pooja Ramakant, Kulranjan Singh et autres

BACKGROUND: Noninvasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP) lacks the carcinoma label, avoiding aggressive therapy, physiological, social and financial impact of cancer diagnosis. Unfortunately, the preoperative diagnosis is still a challenge. Varied incidence of NIFTP has been document with limited …

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A Synchronous Metastatic Growth in Thyroid Gland from Carcinoma Cervix

Suresh Babu, Pooja Ramakant, Anand Mishra, Chanchal Rana et autres

Aim: To describe a rare case of synchronous carcinoma cervix metastasizing to the thyroid, while the patient being of therapy for primary cancer.Background: Metastasis to thyroid primarily occurs from lung, kidney, gastrointestinal tract (GIT), and head and neck.Cervix cancer metastasis to thyroid …

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Intra-Operative Frozen Sections: Experience at A Tertiary Care Centre

preeti agarwal, Sameer Gupta, Kulranjan Singh, Abhinav Arun Sonkar et autres

The present study was conducted to assess error rates with diagnosis using intra-operative frozen sections, and to indicate ways to increase overall performance. Over a period of two years, 227 cases were biopsied intra-operatively. Errors were observed in 14 cases. Four of …

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