Eduardo Martin Arranz

T cell and cytokine signatures as early predictors of response to IL-12/IL-23 inhibition in Crohn’s disease

Eduardo Martin Arranz, Laura García Ramírez, Ana Van Den Rym, Cristina Seijo Suárez et autres

Introduction: Crohn's disease (CD) is a disabling inflammatory disorder with highly variable response to biologic therapies. Despite the availability of multiple biologic agents, a significant proportion of patients experience primary non-response, while others initially respond but subsequently develop secondary loss of response, …

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Evaluación de la remisión histológica en colitis ulcerosa mediante endocitoscopia

Cristina Suárez Ferrer, Eduardo Martin Arranz, J L Rueda García, María Sánchez Azofra et autres

P0322 Global coagulation assays for the assessment of hypercoagulable states in Inflammatory Bowel Diseases.

J L Rueda García, Elena Monzón Manzano, Paula Acuña, Eduardo Martin Arranz et autres

Abstract Background Inpatients with Inflammatory Bowel Disease (IBD) are at risk for thromboembolic events, but the risk for flaring outpatients is less understood1. Global Coagulation Assays (GCA) (Thrombin generation assay using Calibrated Automated Thrombogram [CAT] and Rotational Thromboelastometry [ROTEM]) have emerged as …

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Intensification with Intravenous Ustekinumab in Refractory Crohn’s Disease

Cristina Suárez Ferrer, José Arroyo Argüelles, J L Rueda García, Laura García Ramírez et autres

Background: The rates of clinical and biochemical responses in Crohn’s disease (CD) patients treated with intravenous (IV) ustekinumab (UST) intensification are scarcely described. Methods: Patients with diagnosis of CD who were under intensified IV ustekinumab treatment (130 mg every 4 weeks) were …

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P611 Relation between AntiTNF levels during the induction and clinical and radiological outcomes in perianal Crohn´s disease

Clara Amiama Roig, Cristina Suárez Ferrer, Eduardo Martin Arranz, J L Rueda García et autres

Abstract Background Perianal Crohn's disease(PCD) significantly impacts quality of life with poor long-term prognosis. Anti-tumor necrosis factor(anti-TNF) therapy improves fistula closure rates. However, achieving permanent closure remains challenging. Our aim is to evaluate the relation between antiTNF(infliximab (IFX) and adalimumab(ADA) serum concentrations …

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Evaluation of Genetic Variants Associated with the Risk of Thiopurine-Related Pancreatitis: A Case Control Study from ENEIDA Registry

Iván Guerra, Francisco Barros, María Chaparro, J M Benítez et autres

INTRODUCTION: Risk factors for developing pancreatitis due to thiopurines in patients with inflammatory bowel disease (IBD) are not clearly identified. Our aim was to evaluate the predictive pharmacogenetic risk of pancreatitis in IBD patients treated with thiopurines. METHODS: We conducted an observational …

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The Impact of COVID-19 on Patients with IBD in a Prospective European Cohort Study

Aurélien Amiot, Jean‐François Rahier, Filip Baert, Stéphane Nahon et autres

BACKGROUND AND AIMS: There are concerns regarding the potential impact of the COVID-19 outbreak on patients with inflammatory bowel disease [IBD]. We report on the impact of the COVID-19 outbreak in a European prospective cohort study of patients with IBD. PATIENTS AND …

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P106 Cromoendoscopy versus second generation Narrow band Imaging for dysplasia detection in IBD. An interim analysis of a prospective randomized control trial

Eduardo Martin Arranz, Cristina Suárez Ferrer, Laura García Ramírez, María Sánchez Azofra et autres

Abstract Background Colonic neoplastic risk is increased in long-standing colitis. Chromoendoscopy (CE) is the recommended screening method. Narrow band imaging (NBI) is potentially a more convenient alternative. Few studies have explored the diagnostic yield of second generation NBI (Olympus 190 series) versus …

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Optimization of azathioprine dose in combined treatment with anti-TNF-alpha in inflammatory bowel disease

Javier Lucas Ramos, Cristina Suárez Ferrer, Joaquín Poza Cordón, María Sánchez Azofra et autres

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Optimization of azathioprine dose in combined treatment with anti-TNF-alpha in inflammatory bowel disease

Javier Lucas Ramos, Cristina Suárez Ferrer, Joaquín Poza Cordón, María Sánchez Azofra et autres

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Management of COVID-19 Pandemic in Spanish Inflammatory Bowel Disease Units: Results From a National Survey

Eduardo Martin Arranz, Cristina Suárez Ferrer, Laura García Ramírez, J L Rueda García et autres

BACKGROUND: The outbreak of COVID-19 has rapidly evolved into a pandemic that has represented a challenge to health systems worldwide. Inflammatory bowel disease (IBD) units have been forced to change their practices to address the disease and to ensure the quality of …

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PROGNOSTIC VALUE OF ULTRASOUND ACTIVITY AND PARIETAL HEALING IN PATIENTS WITH CROHN'S DISEASE.

Cristina Suárez Ferrer, Joaquín Poza Cordón, Olivia Crivillén Anguita, Patricia Mayor Delgado et autres

INTRODUCTION: the "treat to target" strategy for the management of patients with Crohn's disease (CD) requires simple, reliable and non-invasive tools for continuous monitoring of the disease. Intestinal ultrasound has been proposed as an emerging technique that could be very useful in …

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