Yan Liu

Swietenine alleviated cardiomyocyte inflammation in diabetic cardiomyopathy by regulating NAMPT/SIRT1

Yuqian Huang, Tian Yao Zhang, Zihao Lu, Shuwen Li et autres

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Abstract 4367586: Safety Profile of the CardioMEMS HF System in Pulmonary Arterial Hypertension: A Pooled Adverse Event Analysis from Three Clinical Studies

Raymond L. Benza, Alexander Rothman, Tatiane Abvreu Dall'Agnol, Rahul Agrawal et autres

Introduction: Pulmonary arterial hypertension (PAH) is a progressive disease. Continuous hemodynamic monitoring may help manage more severe PAH. The CardioMEMS HF System, an implantable pulmonary artery pressure (PAP) monitoring device, has shown promise in PAH management. However, its safety in patients with …

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The Combined Prognostic Value of the Systemic Immune-Inflammation Index and LDL-C in Patients with AMI Undergoing PPCI

Xiuli Zhang, Ailin Liu, Chenyang Li, Yanqing Pan et autres

Background: The combined prognostic impact of the systemic immune-inflammation index (SII) and low-density lipoprotein cholesterol (LDL-C) after primary percutaneous coronary intervention (PPCI) in acute myocardial infarction (AMI) remains unclear. We evaluated their joint predictive value for clinical outcomes. Methods: We retrospectively analyzed …

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Combined Prognostic Value of Systemic Immune-Inflammation Index (SII) and LDL-C in AMI Patients After Primary Percutaneous Coronary Intervention ( PPCI )

Xiuli Zhang, Ailin Liu, Chenyang Li, Yanqing Pan et autres

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The inflammation burden index can predict the cardiac injury following antitumour therapy in lung cancer patients with diabetes

Yumin Wang, Chunyan Huan, Guodong Wang, Huijuan Pu et autres

Lung cancer is a leading cause of cancer-related morbidity and mortality worldwide. Diabetes, as a common metabolic disorder, further increases the risk of cardiovascular damage. Studies have shown that myocardial cells in diabetic patients are more vulnerable to the toxic effects of …

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A new online dynamic nomogram based on the inflammation burden index to predict cardiac injury after antitumor therapy in lung cancer patients

Yumin Wang, Chunyan Huan, Huijuan Pu, Guodong Wang et autres

INTRODUCTION: Cardiotoxicity has become a major concern in cancer patients, especially those with lung cancer, as anti-tumor therapies can significantly affect patient survival and quality of life. This study aims to develop and validate a dynamic nomogram based on the Inflammation Burden …

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Preliminary exploration of poor prognostic factor IL-33 and its involvement in perioperative immunotherapy in stage II–III lung squamous cell carcinoma: a retrospective cohort study

Yan Liu, Pengpeng Liu, Rui Zhang, Nobuhiko Seki et autres

Background: Current knowledge about the prognostic role of interleukin-33 (IL-33) in lung squamous cell carcinoma (LUSC) remains limited, particularly in stage II-III patients. This study aimed to verify the correlation between IL-33 expression and poor prognosis in stage II-III LUSC patients at …

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Electrophysiological correlation between executive vigilance and attention network based on cognitive resource control theory

Tianran Chen, Yan Liu, B.Y. Zhang, Yibo Wu et autres

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Lipid goal attainment in diabetes mellitus patients after acute coronary syndrome: a subanalysis of Dyslipidemia International Study II-China

Tongshuai Guo, Chao Chu, Yang Wang, Mingjun He et autres

BACKGROUND: Lipid management with a low-density lipoprotein cholesterol (LDL-C) goal of < 1.4 mmol/L is recommended for patients with acute coronary syndrome (ACS) and diabetes mellitus (DM) due to a high risk for adverse cardiovascular events. This study evaluated the lipid-lowering treatment …

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Effect of Rivaroxaban vs Enoxaparin on Major Cardiac Adverse Events and Bleeding Risk in the Acute Phase of Acute Coronary Syndrome

Shenghua Zhou, Yichao Xiao, Chonglun Zhou, Zhaofen Zheng et autres

Importance: Parenteral enoxaparin is a preferred anticoagulant used in the acute phase for patients with acute coronary syndrome (ACS). The safety and efficacy of short-term low-dose rivaroxaban in this clinical setting remain unknown. Objective: To compare the safety and efficacy of rivaroxaban …

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Aggressive Afterload Lowering to Improve the Right Ventricle: A New Target for Medical Therapy in Pulmonary Arterial Hypertension?

Carmine Dario Vizza, Irene Marthe Lang, Roberto Badagliacca, Raymond L. Benza et autres

Despite numerous therapeutic advances in pulmonary arterial hypertension, patients continue to suffer high morbidity and mortality, particularly considering a median age of 50 years. This article explores whether early, robust reduction of right ventricular afterload would facilitate substantial improvement in right ventricular …

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Biochanin A Attenuates Ovariectomy-Induced Cognition Deficit via Antioxidant Effects in Female Rats

Yanmeng Zhou, Bingbing Xu, Haiyang Yu, Wei Zhao et autres

Background: Impairment of memory and cognition is one of the major symptoms in women with postmenopausal disorders due to estrogen deficiency, which accounts for the much higher prevalence of Alzheimer’s disease in females. Biochanin A (BCA), a natural phytoestrogen, has been reported …

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