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Profil bibliographique

Claudia-Crina Toma

Informations fournies par OpenAlex. Research Africa ne déduit ni nationalité, ni poste, ni coordonnées personnelles.

17Publications signalées
239Citations signalées
1Affiliations récentes

Les institutions déclarées

Les domaines associés

Natural product bioactivities and synthesisBioactive Compounds and Antitumor AgentsNigella sativa pharmacological applicationsCytokine Signaling Pathways and InteractionsPharmacological Effects of Natural Compounds

Les publications récentes

Accès ouvert 2026 article OpenAlex

Emerging Role of Essential Oils as Modulators of the JAK/STAT Signaling Pathway: A Comprehensive Review

Maria Rosaria Perri, Carmine Lupia, Mary Fucile, Claudia-Crina Toma et autres

Background/Objectives: Essential Oils (EO), complex mixtures of organic compounds, exhibit a wide range of properties useful in the pharmaceutical, cosmetic, perfumery and agri-food fields. In particular, well-recognized EO anti-inflammatory properties push towards the investigation of the mechanisms underlying them. One of the …

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0 citations Pharmaceuticals
Accès ouvert 2026 article OpenAlex

Plant Extracts Downregulating the JAK/STAT Signaling Pathway as a Potential Tool for Psoriasis Management: A Review

Maria Rosaria Perri, Giulia Conforti, Eugenio Provenzano, Maria Itria Giancotta et autres

Background/Objectives: Among the Inflammatory Skin Diseases (ISDs), psoriasis represents a recalcitrant and disabling dermatological disorder associated with perpetuated inflammatory conditions. Recent findings showed that psoriasis pathogenesis is sustained by the interplay of different inflammatory Signaling Pathways, among which the JAK/STAT stands out. …

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1 citation Pharmaceuticals
Accès ouvert 2025 article OpenAlex

Glycyrrhiza glabra L. Extracts Prevent LPS-Induced Inflammation in RAW264.7 Cells by Targeting Pro-Inflammatory Cytokines, Mediators and the JAK/STAT Signaling Pathway

Maria Rosaria Perri, Michele Pellegrino, Claudia-Crina Toma, Pierfrancesco Prezioso et autres

Glycyrrhiza glabra L. is a species widely spread all over the world, with a long tradition of use in folk medicine. Here, raw and hydrolyzed extracts obtained from roots collected in different geographical areas belonging to the Mediterranean basin were standardized as …

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3 citations Foods
Accès ouvert 2025 article OpenAlex

Current Findings on Allium Species with Melanogenesis Inhibitory Activity

Mariangela Marrelli, Maria Pia Argentieri, Vincenzo Musolino, Carmine Lupia et autres

Allium genus (Amaryllidaceae) is widely distributed in the Northern hemisphere. Some species, including garlic and onion, have been used since ancient times as both food ingredients and medicinal plants. Many reviews deal with the chemical constituents, particularly the typical sulfur compounds, as …

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4 citations Plants
Accès ouvert 2025 article OpenAlex

Anti-Obesity and Weight Management-Related Antioxidant Potential Properties of Calabrian Pine Extracts: Pinus nigra Subsp. laricio (Poir.) Maire

Mary Fucile, Carmine Lupia, Maria Francesca Armentano, Mariangela Marrelli et autres

Natural extracts derived from plants have gained attention as potential therapeutic agents for obesity management. Some natural extracts were demonstrated to inhibit pancreatic lipase and alpha amylase, potentially influencing nutrient absorption and contributing to weight management. Pinus nigra subsp. laricio (Poir.) Maire, …

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2 citations Plants
Accès ouvert 2024 review OpenAlex

Effects of Arnica Phytotherapeutic and Homeopathic Formulations on Traumatic Injuries and Inflammatory Conditions: A Systematic Review

Claudia-Crina Toma, Mariangela Marrelli, Monica Puticiu, Filomena Conforti et autres

Arnica L. genus (Asteraceae) comprises perennial herbs native to the temperate and boreal parts of the northern hemisphere. Arnica montana is the main species. It shows different biological activities, such as antioxidant, anti-inflammatory, antibacterial, antifungal, and antitumor effects. The Arnica formulations are …

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15 citations Plants
Accès ouvert 2024 article OpenAlex

Enhancing the nitric oxide inhibitory activity using a combination of plant essential oils and mixture design approach

Mariangela Marrelli, Michele De Luca, Claudia-Crina Toma, Fedora Grande et autres

The synergistic effects of essential oils (EOs) from three aromatic plant species, Foeniculum vulgare subsp. piperitum (C.Presl) Bég. (FV), Origanum heracleoticum L. (OH) and Lavandula austroapennina N.G.Passal., Tundis & Upson. (LA), were evaluated for their inhibitory properties on nitric oxide production in …

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9 citations Heliyon
Accès ouvert 2023 article OpenAlex

Identification of Pinosylvin in Pinus nigra subsp. laricio: A Naturally Occurring Stilbenoid Suppressing LPS-Induced Expression of Pro-Inflammatory Cytokines and Mediators and Inhibiting the JAK/STAT Signaling Pathway

Maria Rosaria Perri, Michele Pellegrino, Mariangela Marrelli, Stefano Aquaro et autres

Stilbenoids, a group of phytoalexin polyphenols produced by plants as a defence mechanism in response to stress conditions, are known for their anti-inflammatory potential. Pinosylvin, a naturally occurring molecule traditionally found in pinus trees, was here identified in Pinus nigra subsp. laricio …

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9 citations Pharmaceuticals
Accès ouvert 2021 article OpenAlex

Beneficial Role of Fruits, Their Juices, and Freeze-Dried Powders on Inflammatory Bowel Disease and Related Dysbiosis

Maria Rosaria Perri, Carmen Romano, Mariangela Marrelli, Ludovica Zicarelli et autres

Inflammatory bowel disease (IBD) is a group of complex chronic inflammatory conditions affecting the gastrointestinal tract. It is linked to a number of genetic and environmental factors able to perturb the immune-microbiome axis. Diet is the most investigated variable both for its …

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12 citations Plants
2021 article OpenAlex

Ranunculusspecies suppress nitric oxide production in LPS-stimulated RAW 264.7 macrophages

Mariangela Marrelli, Caterina Tecla De Marco, Giancarlo Statti, Teodora Alina Neag et autres

Aerial parts and roots from three Ranunculus species were extracted with 70% ethanol. The phytochemical composition was investigated using GC-MS and multivariate data analysis. The total phenolic and flavonoid contents were also assessed. The in vitro inhibitory properties were evaluated as nitrite …

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11 citations Natural Product Research
Accès ouvert 2017 article OpenAlex

POLYPHENOLS PROFILE AND ANTIOXIDANT ACTIVITY OF SOME ROMANIAN RANUNCULUS SPECIES

Teodora Alina Neag, Claudia-Crina Toma, Neli-Kinga Oláh, Aurel Ardelean

The Ranunculus species are mostly known for their toxic effect due to the anemonine and protoanemonine content. This paper studies the polyphenols and the antioxidant activity of four different spontaneous species from Ranunculus genus (Ranunculaceae family) harvested from Western Romania’s spontaneous flora. …

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13 citations Studia Universitatis Babeș-Bolyai Chemia
Accès ouvert 2015 article OpenAlex

Comparative Studies on Polyphenolic Composition, Antioxidant and Diuretic Effects of Nigella sativa L. (Black Cumin) and Nigella damascena L. (Lady-in-a-Mist) Seeds

Claudia-Crina Toma, Neli-Kinga Oláh, Laurian Vlase, Cristina Mogoșan et autres

This study was performed to evaluate the phenolic profile, antioxidant and diuretic effects of black cumin and lady-in-a-mist seeds. In the phenolic profile, differences between the two species are significant. Qualitative and quantitative analyses of the phenolic compounds were performed using a …

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119 citations Molecules

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