Hiroyuki Nishimura

Protective Effect of Uric Acid on Rat Model of Irritable Bowel Syndrome Requires Brain–Gut Communication Through Vagal Cholinergic Pathways

Hiroyuki Nishimura, Masaaki Higashiyama, Akinori Mizoguchi, Akinori Wada et autres

BACKGROUND: Uric acid (UA) is an endogenous antioxidant that protects against neuroinflammatory diseases. Although irritable bowel syndrome (IBS) is considered a disorder of gut-brain interaction, the role of UA in IBS remains unclear. METHODS: An experimental rat model of IBS was induced …

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Fukuoka Industrial Technology Center Supporting Regional Industrial Development

Hiroyuki Nishimura

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Water avoidance stress exacerbates orthotopic pancreatic cancer growth by suppressing cytotoxic T lymphocyte infiltration

Shin Nishii, Yoshikiyo Okada, Akinori Mizoguchi, Nao Sugihara et autres

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Community‐Level Compact City Design, Health Care Provision, and Outcomes of Patients With Stroke

Yukihiro Imaoka, Nice Ren, Soshiro Ogata, Shogo Watanabe et autres

BACKGROUND: The optimal scale of urbanization for stroke health care provision and the potential impact of compact city design on stroke outcomes remain unclear. We investigated the impact of zip code area-level compact city design using the walkability index (WI) and its …

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Imaging assessment of tumor densities and sizes following pazopanib treatment for central nervous system solitary fibrous tumors with multiple extracranial metastases: A case series

Takaya Tsuno, Noritaka Masahira, Kunihiko Numoto, Hitomi Iwasa et autres

Central nervous system (CNS) solitary fibrous tumors (SFTs) are rare but aggressive, often metastasizing to extracranial regions, with no established treatments apart from surgery. Pazopanib, a multikinase angiogenesis inhibitor, is used to treat extracranial SFTs; however, its efficacy for treating CNS SFTs …

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706 SUCCINATE ENHANCES ALLERGIC REACTION IN OVA-INDUCED DIARRHEAL MICE MODELS POSSIBLY VIA SUCCINATE-MAST CELL AXIS.

Kana Ayaki, Yoshikiyo Okada, Masaaki Higashiyama, Kazuki Horiuchi et autres

Initiatives During the COVID-19 Pandemic as a Laser Manufacturer—Development of Masks to Prevent the Spread of Coronavirus—

Hiroyuki Nishimura, Machiko Takaki, Satoshi Takaya

コロナ禍におけるレーザーメーカーとしての取り組みの一つとして，レーザー治療時の感染予防の為の特殊マスクを開発したので，その開発の背景や経緯を記述した．また，それ以外に社会に対する責任を果たしながら，自社の為のみならず，社会全体やお客様の為に行ってきたことをまとめた．

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Evaluation of a creatinine clearance correction equation based on body fat mass in older Japanese patients with diabetes

Sara Utsumi, Yuki Kondo, Yoshihiko Harada, Akira Yoshida et autres

Background: The estimation of creatinine clearance (CCr) in older adult patients with diabetes is subject to deviations from the results of actual measurements because of changes in body composition. In the present study, we aimed to create a correction for the equation …

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Topography of Retinal Ganglion Cells of a Northern Goshawk Accipiter gentilis

Hiroyuki Nishimura, Shoko Nakamuta, Yoshio Yamamoto

The retina of a Northern Goshawk Accipiter gentilis was investigated in a whole-mount preparation using Nissl's staining method. The total number of retinal ganglion cells (RGCs) was 4,427.2×103. The visual streak extended horizontally across the retina with an RGC density of 10.3–22.8×103 …

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Vehicle Simulations development to predict Electric field level distribution based on GB/T18387 measurement method

Keishi Miwa, Toshio Watari, Hiroyuki Nishimura, Hiroki Ogawa

The development of electric vehicles has been progressed, rapidly, to achieve Carbon neutrality by 2050. There have been increasing concerns about Electromagnetic Compatibility (EMC) performance due to increasing power for power trains of vehicles. Because same power train system expands to some …

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Impact of areal socioeconomic status on prehospital delay of acute ischaemic stroke: retrospective cohort study from a prefecture-wide survey in Japan

Hitoshi Fukuda, Yuki Hyohdoh, Hitoshi Ninomiya, Yusuke Ueba et autres

OBJECTIVES: To examine whether the Areal Deprivation Index (ADI), an indicator of the socioeconomic status of the community the patient resides in, is associated with delayed arrival at the hospital and poor outcomes in patients with acute ischaemic stroke from a prefecture-wide …

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Visceral hypersensitivity induced by mild traumatic brain injury via the corticotropin‐releasing hormone receptor: An animal model

Akinori Mizoguchi, Masaaki Higashiyama, Akinori Wada, Hiroyuki Nishimura et autres

BACKGROUND: Mild blast-induced traumatic brain injury (bTBI) induces various gut symptoms resembling human irritable bowel syndrome (IBS) as one of mental and behavioral disorders. However, the underlying mechanisms remain unclear. We investigated whether the extremely localized brain impact extracranially induced by laser-induced …

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