Íris Rabinovich

Mastectomia redutora de risco com reconstrução imediata: estudo exploratório do bem-estar psicossocial e sexual por meio do BREAST-Q™

Isabela Chaves Monteiro Soares, Enilze Maria de Souza Fonseca Ribeiro, Guilherme Batalha, Michelli Esteves de Souza et autres

RESUMO Introdução: A mastectomia redutora de risco reduz significativamente a incidência de câncer de mama em mulheres com predisposição genética. Entretanto, seus impactos sobre o bem-estar psicossocial e sexual ainda são pouco explorados, especialmente em pacientes sem diagnóstico prévio da doença. Objetivo: …

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Risk-reducing mastectomy with immediate reconstruction: an exploratory study of psychosocial and sexual well-being using the BREAST-QTM

Isabela Chaves Monteiro Soares, Enilze Maria de Souza Fonseca Ribeiro, Guilherme Batalha, Michelli Esteves de Souza et autres

ABSTRACT Introduction: Risk-reducing mastectomy significantly decreases the incidence of breast cancer in women with a genetic predisposition. However, its effects on psychosocial and sexual well-being remain insufficiently explored, particularly among women without a previous diagnosis of breast cancer. Objective: To evaluate the …

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A prospective evaluation of breast satisfaction and expectation in preoperative immediate breast reconstruction patients

Flávia Kuroda, Cı́cero de Andrade Urban, Maíra Teixeira Dória, Íris Rabinovich et autres

Breast reconstruction has an important positive contribution to the quality of life of breast cancer patients. However, a large proportion of breast cancer survivors have unmet expectations surrounding reconstruction. This study aimed to delineate factors affecting preoperative native breast satisfaction and expectations …

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Three-dimensional Simulation on Patient-reported Outcomes Following Oncoplastic and Reconstructive Surgery of the Breast: A Randomized Trial

Flávia Kuroda, Cicero A. Urban, Maíra Dória, Íris Rabinovich et autres

Background: Three-dimensional (3D) imaging using computer simulations is an evolving technology. There is a lack of strong data on the use of this technology for oncoplastic (OP) and reconstructive surgery. Methods: A prospective, randomized, single-center trial including breast cancer patients undergoing OP …

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High-throughput proteomics of breast cancer subtypes: Biological characterization and multiple candidate biomarker panels to patients' stratification

Alexandre Luiz Korte de Azevedo, Talita Helen Bombardelli Gomig, MICHEL KOVALSKI BATISTA, Fabrício Klerynton Marchini et autres

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A three-sequence dynamic contrast enhanced abbreviated MRI protocol to evaluate response to breast cancer neoadjuvant chemotherapy

Eduardo Carnier Dornelas, Christiane S. Kawassaki, Márcia Olandoski, Carolina de L. Bolzon et autres

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Prospective study: Impact of breast magnetic resonance imaging on oncoplastic surgery and on indications of mastectomy in patients who were previously candidates to breast conserving surgery

Karina Furlan Anselmi, Cicero A. Urban, Maíra Teixeira Dória, Ana Paula Martins Sebastião et autres

Background: Routine use of magnetic resonance imaging (MRI) in the staging of patients with early breast cancer is still controversial. Oncoplastic surgery (OP) allows for wider resections without compromising the aesthetic results. This study aimed to assess the impact of preoperative MRI …

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Abstract P2-14-18: Oncological Outcomes of Nipple-Sparing Mastectomy after Neoadjuvant Chemotherapy

Íris Rabinovich, Leonardo Paese Nissen, Isabela Chaves Monteiro Soares, Alessandra C. Fornazari et autres

Abstract Introduction: Surgery is the mainstay treatment of breast cancer and has been improving in aesthetic outcomes even in locally advanced disease. Radical mastectomies are being replaced by less aggressive surgeries with immediate breast reconstruction. Nipple-Sparing Mastectomy (NSM) preserves Nipple Areolar Complex …

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Oncological safety of nipple-sparing mastectomy after neoadjuvant chemotherapy: a systematic review

Leonardo Paese Nissen, Isabela Chaves Monteiro Soares, Rubens Silveira de Lima, Cı́cero de Andrade Urban et autres

BACKGROUND: the use of nipple-sparing mastectomy (NSM) in local advanced breast cancer after neoadjuvant chemotherapy (NQT) is increasing, despite few studies on the subject. The aim of this systematic review was to determine the safety of NSM after neoadjuvant chemotherapy. METHODS: for …

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Segurança oncológica da mastectomia conservadora do mamilo após quimioterapia neoadjuvante: revisão sistemática

Leonardo Paese Nissen, Isabela Chaves Monteiro Soares, Rubens Silveira de Lima, Cı́cero de Andrade Urban et autres

RESUMO Introdução: O uso de mastectomia preservadora de complexo aréolo-papilar (MPCAP) no câncer de mama localmente avançado após quimioterapia neoadjuvante (QTN) é crescente, apesar de ainda haver poucos estudos abordando o assunto. O objetivo desta revisão sistemática foi determinar a segurança da …

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Prepectoral Direct-to-Implant Breast Reconstruction without Placement of Acellular Dermal Matrix or Mesh after Nipple-Sparing Mastectomy

Cı́cero de Andrade Urban, Alessandra Fornazari, Gastón Berman, Cléverton Spautz et autres

BACKGROUND: The aim of this study was to report the results of prepectoral direct-to-implant reconstruction in nipple-sparing mastectomy without acellular dermal matrices or mesh. METHODS: A multicenter cohort of patients undergoing prophylactic or therapeutic nipple-sparing mastectomy was included from 2013 to 2020. …

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Transcribed Ultraconserved Regions Are Associated with Clinicopathological Features in Breast Cancer

Érika Pereira Zambalde, Douglas Adamóski, Daniela Fiori Gradia, Íris Rabinovich et autres

Ultraconserved regions (UCRs) are 481 genome segments, with length longer than 200 bp, that are 100% conserved among humans, mice, and rats. The majority of UCRs are transcriptionally active (T-UCRs) as many of them produce non-coding RNAs. In a previous study, we …

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