Jianjun Ren

Long Non-Coding RNA CASC2 Drives Cholangiocarcinoma Progression via HMGCS1-Mediated Lipid Metabolism

Rui Ting Wang, Shaojie Liu, Na Wang, Guoliang Liu et autres

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Targeting AGTPBP1 inhibits pancreatic cancer progression via regulating microtubules and ERK signaling pathway

Ding-zhong Li, Zhe-yu Yang, Asi leng, Qian Zhang et autres

BACKGROUND: AGTPBP1 is a cytosolic carboxypeptidase that cleaves poly-glutamic acids from the C terminus or side chains of α/β tubulins. Although its dysregulated expression has been linked to the development of non-small cell lung cancer, the specific roles and mechanisms of AGTPBP1 …

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A modified kidney-sparing portal vein arterialization model of heterotopic auxiliary liver transplantation increases liver IL-6, TNF-α, and HGF levels and enhances liver regeneration: an animal model

Jun Li, Jianjun Ren, JunJing Zhang, Xing‐Kai Meng

BACKGROUND AND AIM: The success of partial donor liver transplantation is affected by the implantation site of the donor liver and the vascular reconstruction approach. We investigated the effects of different donor liver implantation sites and vascular reconstruction approaches on liver regeneration …

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Long-term exposure to genistein inhibits the proliferation of gallbladder cancer by downregulating the MCM complex

Yajun Geng, Shili Chen, Yang Yang, Huijie Miao et autres

Soy isoflavones are natural tyrosine kinase inhibitors closely associated with decreased morbidity and mortality of various tumors. The activation of tyrosine kinases such as ERBB2 is the mechanism by which cholecystitis transforms into gallbladder cancer (GBC), therefore, it is important to investigate …

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How to learn the cardiac anatomy efficiently and interestingly?

Riwa Hao, Dong Li, Yuanzhen Ma, Jianjun Ren et autres

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USP22 Protects Against Myocardial Ischemia–Reperfusion Injury via the SIRT1-p53/SLC7A11–Dependent Inhibition of Ferroptosis–Induced Cardiomyocyte Death

Shuxian Ma, Linyan Sun, Wenhao Wu, WU Jiang-li et autres

Myocardial ischemia-reperfusion (MI/R) injury is characterized by iron deposition and reactive oxygen species production, which can induce ferroptosis. Ferroptosis has also been proposed to promote cardiomyocyte death. The current study sought to define the mechanism governing cardiomyocyte death in MI/R injury. An …

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“Hand for liver” — A new approach for learning liver segmentation for medical students

Qian Zhang, Jianjun Ren, Jianliang Qiao

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[Male infertility - related gene knockout mouse models].

Wenxiu Li, Yan-Chao Bian, Jianjun Ren, Rui Xiao

The pathogenesis of male infertility is rather complicated. The establishment of animal models, especially mouse models, of male infertility, provides a model basis for the studies of the roles and molecular mechanisms of infertility-related genes. Currently there are mainly three types of …

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Establishment of a Canine Training Model for Digestive Tract Reconstruction after Pancreaticoduodenectomy

Jingrui Yang, Rui Xiao, Jiang Zhou, Lu Wang et autres

PURPOSE: Practical training models can be a viable and effective educational tool that allows surgeons to acquire specific surgical techniques or skills. However, a suitable animal training model for reconstruction after a pancreaticoduodenectomy (PD) has not yet been reported. Therefore, we explored …

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“Hands and feet” figural teaching method in portal vein traffic branch: A surgeon's teaching experience

Lu Wang, Jingrui Yang, Jiang Zhou, Wen Bo et autres

Figure 1 "Hands and feet" figural teaching method in portal vein traffic branch.

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Extrahepatic biliary tract angle is a risk factor for biliary tract injury in laparoscopic cholecystectomy: A surgeon's experience

Yang Jia-yuan, Jianjun Ren, Junhua Jin, Zhen-fang Yang

Summary In our clinical work, we found that there is a certain angle in the extrahepatic biliary system, that is to say, there is an angle between the extension line of the lower common bile duct and the upper duodenal segment of …

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Pancreatic tail and spleen “shape frozen” causes difficulty in Splenectomy – Application of the pancreatic body suspended blocking hilus of spleen method

Jiaxing Wang, Qian Zhang, Lu Wang, Jianjun Ren et autres

Pancreatic tail and spleen "shape frozen" causes difficulty in Splenectomy e Application of the pancreatic body suspended blocking hilus of spleen method Dear Editor,We recently read Dorota Radkowiaka et al Surgery of the article published in the International Journal "20 years' experience …

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