Shaojie Liu

A 3D Graphene Oxide Model Reveals Fine Particulate Matter Induced Cell Cycle Dysregulation in Neural Stem Cells

Siqi Li, Huiyun Chang, Mengjie Gao, Wenlou Zhang et autres

Fine particulate matter (PM2.5) exposure increases the risk of neurodevelopmental abnormalities by disrupting neural stem cell (NSC) proliferation and cell cycle homeostasis, which are critical for normal neurodevelopment. This study investigated the impact of fine particulate matter (PM2.5) on NSC proliferation and …

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Microplastic-associated gut microbial profile and antibiotic resistance in preschool children: a multicentre cross-sectional study in China

Xinyuan Liu, Hua Cai, Long Zhao, Dandan Ke et autres

BACKGROUND: Microplastics (MPs) are ubiquitous in ecosystems and present in the human body, causing a worldwide environmental issue. However, the extent of human exposure to MPs remains largely unknown. Although mice exposed to MPs exhibit gut microbiota dysbiosis, the impact of MPs …

kr, cn, us (code pays fourni par la source)

Editorial: Dietary pattern and metabolic syndrome

Shaojie Liu, Yingnan Jia, Mengyun Luo

Metabolic Syndrome (MetS), a clustering of obesity, hypertension, dysglycemia, and dyslipidemia, is a major global driver of type 2 diabetes and cardiovascular disease. Its rising prevalence represents a formidable public health challenge. While diet is a cornerstone of MetS management, the effectiveness …

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Active-targeting biomimetic nanosystem for prostate cancer enhances radiotherapy efficacy by inducing ferroptosis

Zhihao Hu, Hongji Li, Kai Gan, Yu Li et autres

Radioresistance and off-target toxicity remain major challenges in prostate cancer (PCa) radiotherapy. Here, we report a biomimetic nanoplatform (Au/MOF-FIN@M-gy1) that synergistically enhances radiation deposition and ferroptosis for precision radiosensitization. By engineering macrophage membranes with prostate-specific membrane antigen (PSMA)-targeting nanobodies (gy1), we achieve …

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Rhizosphere phenolics by urban plants drive laccase-like oxidative conditions and selective degradation of phenolic/anilinic antibiotics

Zhimin Zhou, Shaowei Wu, Yuxin Chen, Yongpeng Li et autres

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Cryptographic Metasurface Enabled High-Security Information Authentication Using Dual-Beam Off-Axis Illumination

Zhenfei Li, Yuhang Zhang, Shaojie Liu, Jiaru Lin et autres

Optical information security has become paramount in data-driven technological systems, where metasurface holography has emerged as a transformative paradigm for high-density optical encryption. However, conventional methods remain constrained by fundamental limitations: multiplexed architectures suffer from inherent interchannel crosstalk, while complex cryptographic algorithms …

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CXCL12-targeting siRNA nanoparticles alleviate immunosuppression and inhibit tumor progression in esophageal squamous cell carcinoma

Shuyao Zhang, Hong Jiang, Chengkuan Zhao, Yanli Lei et autres

Esophageal squamous cell carcinoma (ESCC) is associated with a highly immunosuppressive tumor microenvironment (TME), driven in part by cancer-associated fibroblasts (CAFs) that promote immune evasion through the secretion of CXCL12. CXCL12 interacts with the CXCR4 receptor on immune cells, disrupting CD8+ T …

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Occurrence and distribution of melamine and its derivatives in the diverse aquatic environments in China

Shaojie Liu, Jing‐Li Fan, Yifei Wang, Zhanren Liu et autres

Due to the special characteristics of low octanol-water partition coefficient and high-water solubility, melamine (MEL) and its derivatives released from daily products will be preferentially allocated to aquatic environments. However, no study has reported the occurrence and distribution of MEL and its …

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Microplastics exposed by respiratory tract and exacerbation of community-acquired pneumonia: The potential influences of respiratory microbiota and inflammatory factors

Shaojie Liu, Jianheng Zheng, Zhiping Yang, Meizhen Li et autres

The relationships between microplastics (MP) exposure through respiratory and exacerbation of community-acquired pneumonia (CAP), as well as the potential influences of respiratory microbiota and inflammatory factors remain unknown in adults. Therefore, we conducted a cross-sectional study involving 50 non-severe CAP (NSCAP) and …

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Regulatory T Cell Infiltration-Driven Single-Cell Transcriptomic Analysis Identifies SAP18 as a Prognostic Marker for Esophageal Squamous Cell Carcinoma

Jianxiang Huang, Hanshuo Zhang, Xinyue Lin, Xiaolong Wu et autres

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Peri-URban ecosystems (PURE) promote faster antibiotic and ARG degradation: Insights from a microcosm experiment

Zhimin Zhou, Yinsen Lei, Panagiotis Karanis, Dionisio Zaldívar et autres

cn, cy, de, cu (code pays fourni par la source)

Machine learning-based exploration of the associations between multiple minerals' intake and thyroid dysfunction: data from the National Health and Nutrition Examination Survey

Shaojie Liu, Wei Y. Huang, Yifei Wang, Hongjin Li et autres

Objectives The associations between various minerals' intake and thyroid dysfunction (TD), including hyperthyroidism and hypothyroidism, are still inconclusive, which may be attributed to the potential synergistic effects among various minerals. Methods The data were obtained from the National Health and Nutrition Examination …

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