Maria Protopapa

Safety and efficacy of delivering systemic treatments concomitantly with whole-brain radiotherapy: a prospective, observational, single-institution study

Maria Protopapa, Kalliopi Platoni, Michalis Psarras, Styliani-Theonymfi Nikoloudi et autres

Aim: The aim of our study was to evaluate the safety and efficacy of delivering systemic treatments concurrently with whole-brain radiotherapy (WBRT). Methods: A single-institution, prospective observational study was conducted in Athens, Greece, including 99 patients treated with WBRT for brain metastases …

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266 Outcome Evaluation of Volume-Staged Stereotactic Radiosurgery for Cerebral Arteriovenous Malformations

Georgios Mantziaris, Bardia Hajikarimloo, Salem M Tos, Stylianos Pikis et autres

INTRODUCTION: Single-session stereotactic radiosurgery (SRS) has limited role for large arteriovenous malformations (AVM). Volume-staged SRS (VS-SRS) is used to optimize outcomes but studies reporting results are limited. METHODS: This multicenter retrospective cohort of 378 patients from 21 centers reports results of VS-SRS …

Real-World Data on the Safety and Efficacy of SBRT for Central and Ultra-Central Lung Tumors: A Retrospective Multi-Center Cohort

Anna G. Zygogianni, Andromachi Kougioumtzopoulou, Kalliopi Platoni, Maria Protopapa et autres

Background/Objectives: The use of stereotactic body radiotherapy (SBRT) for centrally and ultra-centrally located early-stage non-small cell lung cancer (NSCLC) remains clinically challenging due to the proximity of critical mediastinal organs at risk and the limited prospective evidence, particularly for ultra-central disease. Real-world …

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Volumetric Modulated Arc Therapy Versus Dynamic Conformal Arc Therapy for Single Isocenter Stereotactic Radiotherapy of Multiple Brain Metastases

Theodoros Stroubinis, Maria Giannopoulou, Despoina Stasinou, Michalis Psarras et autres

INTRODUCTION: Stereotactic radiosurgery is a highly precise radiotherapy technique widely used for the management of brain metastases. While VMAT enables highly conformal dose distributions, it is often associated with increased plan complexity and longer delivery times. Optimized dynamic conformal arc therapy (OptDCA) …

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Outcome Evaluation of Volume-Staged Stereotactic Radiosurgery for Cerebral Arteriovenous Malformations

Georgios Mantziaris, Bardia Hajikarimloo, Salem M Tos, Stylianos Pikis et autres

BACKGROUND AND OBJECTIVES: Single-session stereotactic radiosurgery (SRS) has limited role for large arteriovenous malformations (AVM). Volume-staged SRS (VS-SRS) is used to optimize outcomes, but studies reporting results are limited. METHODS: This multicenter retrospective cohort of 378 patients from 21 centers reports results …

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Stereotactic radiosurgery for brain metastases

Stylianos Pikis, Maria Protopapa, Georgios Mantziaris, Mahmoud Osama et autres

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Recent Advances in Radiotherapy of Lung Cancer

Maria Protopapa, M. Balafouta, Georgia Lymperopoulou, Andreas Koulouris et autres

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Identifying Key Factors for Predicting the Age at Peak Height Velocity in Preadolescent Team Sports Athletes Using Explainable Machine Learning

Nikolaos-Orestis Retzepis, Alexandra A. Avloniti, Christos Kokkotis, Maria Protopapa et autres

Maturation is a key factor in sports participation and often determines the young athletes’ characterization as a talent. However, there is no evidence of practical models for understanding the factors that discriminate children according to maturity. Hence, this study aims to deepen …

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Stereotactic radiosurgery for brain metastases from human epidermal receptor 2 positive breast Cancer: an international, multi-center study

Stylianos Pikis, Georgios Mantziaris, Maria Protopapa, Salem M Tos et autres

PURPOSE: To report patient outcomes and local tumor control rates in a cohort of patients with biopsy-proven HER-2 positive breast cancer treated with stereotactic radiosurgery (SRS) for brain metastases (BM). METHODS: This international, retrospective, multicenter study, included 195 female patients with 1706 …

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Stereotactic Radiosurgery for Brain Metastases from Human Epidermal Receptor 2 Positive Breast Cancer: An International, Multi-center Study

Stylianos Pikis, Georgios Mantziaris, Maria Protopapa, Roman O. Kowalchuk et autres

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Single-Session Stereotactic Radiosurgery After Failed Repeat Radiosurgery for Cerebral Arteriovenous Malformations

Stylianos Pikis, Georgios Mantziaris, Maria Protopapa, Ahmed Taha Elsayed Shaaban et autres

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Third Stereotactic Radiosurgery for Residual Arteriovenous Malformations: A Retrospective Multicenter Study

Stylianos Pikis, Georgios Mantziaris, Chloé Dumot, Ahmed Taha Elsayed Shaaban et autres

BACKGROUND AND OBJECTIVES: There are no studies evaluating the efficacy and safety of more than 2 stereotactic radiosurgery (SRS) procedures for cerebral arteriovenous malformations (AVM). The aim of this study was to provide evidence on the role of third single-session SRS for …

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