Hongju Yang

[In vivo study of posterior cruciate ligament reconstruction augmented by a novel elastic internal tension-relieving augmentation tape in Diannan miniature pigs].

Zhengliang Shi, Zhaohui Ruan, Hongju Yang, Kejia Li et autres

Objective: To explore the biosafety of a novel elastic internal tension-relieving augmentation tape (hereinafter referred to as "novel tension-relieving tape") for posterior cruciate ligament (PCL) reconstruction and its regulatory effects on graft healing and tendon-bone integration via a Diannan miniature pig PCL …

cn (code pays fourni par la source)

Biomechanical Superiority of the Chinese Knotting Technique in Posterior Cruciate Ligament Reconstruction: A Cadaveric Study

Zhengliang Shi, Rui Han, Ping Yuan, Zhaohui Ruan et autres

OBJECTIVE: We previously developed a novel internal tension-relieving augmentation suture, the Chinese knotting technique (CKT), which demonstrated better knee kinematic recovery and clinical outcomes when assisting posterior cruciate ligament (PCL) reconstruction. This study evaluated the biomechanical effect of the CKT in cadaveric …

cn (code pays fourni par la source)

ETS1-driven transcriptional activation of ACSL4 mediates hypoxia-induced ferroptosis in anterior cruciate ligament fibroblasts

Zhengliang Shi, Rui Han, Zhaohui Ruan, Hongju Yang et autres

Background Anterior cruciate ligament (ACL) injury is a prevalent sports-related trauma that severely compromises knee joint function. The hypoxic microenvironment is a critical pathological driver of fibroblast dysfunction following ACL injury; however, whether ferroptosis participates in this process and the underlying regulatory …

cn (code pays fourni par la source)

[Application of internal brace ligament augmentation technology in repair and reconstruction of cruciate ligament injuries].

Hongju Yang, Zhengliang Shi, Zhaohui Ruan, Kejia Li et autres

Objective: To review the application progress of internal brace ligament augmentation (IBLA) technology in the repair and reconstruction of anterior cruciate ligament (ACL) or posterior cruciate ligament (PCL) injuries, and to clarify the development trends of IBLA technology. Methods: biomechanical studies, animal …

cn (code pays fourni par la source)

[Research progress on enhanced recovery after posterior cruciate ligament reconstruction].

Zhengliang Shi, Yanlin Li, Hongju Yang, Kejia Li et autres

Objective: To summarize research progress on enhanced recovery after posterior cruciate ligament (PCL) reconstruction, clarify the core contradictions, effective intervention methods, and evaluation shortcomings in current clinical practice, and provide theoretical support for optimizing clinical rehabilitation strategies. Methods: Relevant domestic and international …

cn (code pays fourni par la source)

Ruminococcus bromii alleviates constipation by pullulanase-driven resistant starch degradation and microbiota modulation

Rong Li, Qianqian Yang, Jian He, Min Li et autres

Constipation is a prevalent gastrointestinal disorder associated with alterations in the gut microbiota. However, the potential microbial targets and their underlying mechanisms remain to be explored. Our analysis found the genus Ruminococcus was depleted in constipated patients. We then tested four species, …

cn (code pays fourni par la source)

MOMMY study profile: An integrative early‐life multi‐omics cohort in China

Lin Zhang, Yingzhi Liu, Shilan Wang, Jessica Yuet‐Ling Ching et autres

Large-scale, prospective birth cohorts capturing the complex interplay between the gut microbiome, host biology, and environmental exposures are crucial to understanding early-life health but remain scarce, particularly within Asian populations. To address this gap, we established the MOMMY cohort (The MOther-infant Microbiota …

hk, us, cn (code pays fourni par la source)

Human Albumin infusion in liver Cirrhosis and overt Hepatic Encephalopathy (HACHE): protocol of an investigator-initiated, open-label, multicentre, randomised controlled trial

Qianqian Li, Huan Tong, Xuemei Liu, Fei Liao et autres

INTRODUCTION: Hepatic encephalopathy (HE), a severe complication of decompensated cirrhosis, is characterised as neurocognitive dysfunction. Emerging evidence suggests the potential role of human albumin infusion for the treatment of HE, but its optimal dosage remains undefined. Therefore, we planned a randomised controlled …

cn, nl, it (code pays fourni par la source)

Analysis of parkinson’s disease patients with Gastrointestinal symptoms using structural and functional magnetic resonance imaging

Yuchao Tai, Wei Huang, Yongyun Zhu, Bin Liu et autres

cn (code pays fourni par la source)

In vivo systematic analysis of microbiota-prebiotic crosstalk reveals a synbiotic that effectively ameliorates DSS-induced colitis in mice

Qianwen Peng, Puzi Jiang, Liwen Yi, Yun Li et autres

Systematic identification of prebiotic–microbe interactions is essential for developing precision microbiome-targeted interventions to improve human health. In this study, we developed an in vivo systematic screening platform to evaluate microbiota-prebiotic crosstalk and applied it to identify a synbiotic combination effective against dextran …

cn (code pays fourni par la source)

Macrophage Vesicles‐Loaded NIR‐II AIEgens for Precise In Situ Fluorescence Imaging of Atherosclerosis

Zhiheng Luo, Xipeng Li, Caifa You, Laiping Fang et autres

Precise diagnosis of atherosclerosis (AS) is a crucial strategy for reducing acute cardiovascular events. Herein, a macrophage membrane (MM)-camouflaged biomimetic vesicle loaded with near-infrared-II (NIR-II) aggregation-induced emission luminogens (AIEgens) (P4TT@MM) is proposed to achieve localized in vivo imaging of atherosclerosis. The AIEgens …

cn (code pays fourni par la source)

Corrigendum to “The role of the right atrial appendage and right atrium in post-radiofrequency ablation recurrence in different types of atrial fibrillation [Clin Radiol 79 (11) (2024) e1312–e1320]”

Tao Pan, Xiaofeng Tian, Yi Liu, Hongju Yang et autres

cn (code pays fourni par la source)