Accès ouvert
2025
article
OpenAlex
Minjun Wang, Fei Chen, Junling Gao, Qinggui Liu et autres
BACKGROUND & AIMS: Liver fibrosis, a common outcome of chronic liver diseases, is generally considered irreversible. Upregulation of clusterin (CLU), a secreted glycoprotein, occurs in several degenerative diseases and is suggested to have protective effects; however, its potential in treating or reversing …
cn
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Accès ouvert
2025
article
OpenAlex
Kai Yang, Fei Chen, Aiping Tian, Long Deng et autres
Objectives: Liver fibrosis staging and etiology diagnosis are critical for patient management, but non-invasive methods remain challenging. This study aims to evaluate the performance of radiomics models using 2D shear wave elastography (2D-SWE) of the liver and spleen for liver fibrosis staging …
cn
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Accès ouvert
2025
article
OpenAlex
Lan Wang, Ruiling He, Lili Zhao, Jia Wang et autres
ABSTRACT Aims Bleeding from gastroesophageal varices (GEV) is a medical emergency associated with high mortality. We aim to construct an artificial intelligence‐based model of two‐dimensional shear wave elastography (2D‐SWE) of the liver and spleen to precisely assess the risk of GEV and …
cn, us
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Accès ouvert
2025
article
OpenAlex
Bingtian Dong, Ruiling He, Shenghong Ju, Yuping Chen et autres
BACKGROUND/AIMS: A large percentage of patients undergoing esophagogastroduodenoscopy (EGD) screening do not have esophageal varices (EV) or have only small EV. We evaluated a large, international, multicenter cohort to develop a novel score, termed FIB-4plus, by combining the fibrosis-4 (FIB-4) score, liver …
cn, hr, ch, kr
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Accès ouvert
2025
article
OpenAlex
Fei Chen, Jingjing An, Long Deng, Jing Wang et autres
BACKGROUND: US tools to quantify hepatic steatosis have recently been made clinically available by different manufacturers, but comparative data on their consistency are lacking. OBJECTIVE: US tools to quantify hepatic steatosis have recently been made clinically available by different manufacturers, but comparative …
cn
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Accès ouvert
2023
article
OpenAlex
Linghua Kong, Tao Xu, Runtian Wan, Fei Chen
BACKGROUND: Human papillomavirus (HPV) has been confirmed as a major causative factor for malignant transformation of cervical epithelial cells and for the development of cervical intraepithelial neoplasia (CIN) and invasive cervical cancer. We carried out this study to investigate the association of …
cn
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Accès ouvert
2023
article
OpenAlex
Fei Chen, Yaning Yao, Zhen Li, Long Deng et autres
Patients with chronic liver disease progressed to compensated advanced chronic liver disease (cACLD), the risk of liver-related decompensation increased significantly. This study aimed to develop prediction model based on individual bile acid (BA) profiles to identify cACLD. This study prospectively recruited 159 …
cn
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