Runtian Wan

Immediate risk and 5-year cumulative risk of high-grade cervical lesions in high-risk HPV-positive patients with minor cytological abnormalities: a retrospective single-center study in China

Linghua Kong, Runtian Wan, Shuanzheng Zhao

BACKGROUND: Although minor cytological abnormalities predict a low risk of high-grade lesions, their high reporting rates lead to a considerable number of high-grade lesion cases. We carried out this study to analyze the immediate risk and 5-year cumulative risk of high-grade cervical …

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Mogroside-rich extract alleviates the inflammation state in polycystic ovary syndrome rats through modulating intestinal microbiota-metabolic axis and suppressing the NF-κB/NLRP3 pathway

Shuai Li, Renhong Lu, Boping Zhou, Runtian Wan et autres

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Equol Alleviates the In Vitro Aging‐Induced Disruption of Porcine Oocytes

Rui Chen, Runtian Wan, Ke Peng, Xinxin Liu et autres

Oocyte quality is crucial for determining the subsequent embryo developmental capacity and reproductive outcomes. However, aging is detrimental to oocyte quality. Previous studies have demonstrated that soy isoflavones have positive effects on the reproductive performance of female pigs. Equol, the primary metabolite …

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Equol promotes the in vitro maturation of porcine oocytes by activating the NRF2/KEAP1 signaling pathway

Sai Jin Xiao, Ke Peng, Rui Chen, Xinxin Liu et autres

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The splicing factor SF3B1 is essential for proper alternative splicing and zygotic genome activation in early porcine embryos

Yanan Zhao, Hua Zhang, Boping Zhou, Runtian Wan et autres

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[A multicenter study on the accuracy of PAX1/JAM3 dual genes methylation testing for screening cervical cancer].

Xiao Shang, Lijuan Kong, Xing Xiao, Runtian Wan et autres

test in cervical exfoliated cells has excellent accuracy for the diagnosis of both CIN2+and CIN3+, which is superior to traditional screening protocols and screening strategies.

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Immediate histologic correlation in patients with different HPV genotypes and ages: a single center analysis in China

Linghua Kong, Tao Xu, Runtian Wan, Fei Chen

BACKGROUND: Human papillomavirus (HPV) has been confirmed as a major causative factor for malignant transformation of cervical epithelial cells and for the development of cervical intraepithelial neoplasia (CIN) and invasive cervical cancer. We carried out this study to investigate the association of …

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[The role of DNA methylation in the screening of endometrial cancer in postmenopausal women].

Lijuan Kong, Xing Xiao, Runtian Wan, Xue Chao et autres

In postmenopausal women with suspected endometrial lesions, the accuracy of cervical cytology DNA methylation is better than other noninvasive clinical indicators for the screening of endometrial cancer. DNA methylation combined with TVS can further improve the sensitivity of screening.

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Retrospective Analysis of the Association Between Cervical Squamous Intraepithelial Lesions and Human Papillomavirus Genotypes

Linghua Kong, Tao Xu, Runtian Wan, Yang Xiang

Abstract Background: Human papillomavirus (HPV) has been confirmed as a major causative factor for malignant transformation of cervical epithelial cells and for the development of cervical intraepithelial neoplasia (CIN) and invasive cervical cancer. Methods: We collected the cervical cell samples of women …

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