Sai Chen

Mechanistic Study on Regulating the Aspect Ratio of Silver Lines in Dry Aerosol Jet Printing via Focusing Ratio

Y Zhang, Xiayun Shu, Sai Chen, Guangfu QIU et autres

This study systematically investigated the regulatory mechanism of the focusing ratio σ (σ = sheath gas flow rateQs/ carrier gas flow rateQc) on the morphology of conductive silver lines, aiming to achieve high resolution and high aspect ratio in dry aerosol jet …

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Functionally segmented small-diameter vascular grafts with excellent mechanical matchability prepared by emulsion spinning method

Ziru Sun, Enxiang Jiao, Chengchen Deng, Meihong Xu et autres

MiR-34a-5p suppresses cutaneous squamous cell carcinoma progression by targeting SIRT6

Sai Chen, Muxing Yuan, Tong Wu, Tianqi Wu et autres

Cutaneous squamous cell carcinoma (cSCC) is a malignant tumor originating from epidermal or appendageal keratinocytes, with a rising incidence in recent years. Understanding the molecular mechanism driving its development is crucial. This study aims to investigate whether miR-34a-5p is involved in the …

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Expression analysis and biological regulation of silencing regulatory protein 6 (SIRT6) in cutaneous squamous cell carcinoma

Sai Chen, H Chen, Xu Wang, Dongmei Zhang et autres

BACKGROUND: Cutaneous squamous cell carcinoma (CSCC) is one of the most common types of skin cancer worldwide. Therefore, the identification of biomarkers associated with CSCC progression could aid in the early detection of high-risk squamous cell carcinoma and the development of novel …

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Causal effects of dietary habits on COVID-19 susceptibility, hospitalisation and severity: a comprehensive Mendelian randomisation study

Xiaoping Li, Ningning Wang, Congjie Wang, Sai Chen et autres

Abstract This study aimed to investigate the causal effect of dietary habits on COVID-19 susceptibility, hospitalisation and severity. We used data from a large-scale diet dataset and the COVID-19 Host Genetics Initiative to estimate causal relationships using Mendelian randomisation. The inverse variance …

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Identification of potential genes correlated with breast cancer metastasis and prognosis

Chao Tan, Fang Zuo, Mingqian Lu, Sai Chen et autres

We aimed to screen, via bioinformatics analyses, potential gene markers related to BC metastasis and prognosis. A gene expression dataset (GSE102818) and relevant clinical information were downloaded from the GEO database and TCGA, respectively. Then, differentially expressed genes (DEGs) were identified between …

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Impact-resistant membranes from electrospun fibers with a shear-thickening core

Wenhua Cai, Sai Chen, Rong Zhang, Xuechen Wang

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Early Death and Survival of Patients With Acute Promyelocytic Leukemia in ATRA Plus Arsenic Era: A Population-Based Study

Hong‐Hu Zhu, Yafang Ma, Yu Kang, Guifang Ouyang et autres

Most randomized trials for acute promyelocytic leukemia (APL) have investigated highly selected patients under idealized conditions, and the findings need to be validated in the real world. We conducted a population-based study of all APL patients in Zhejiang Province, China, with a …

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Fabrication and Characterization of Electrospun Poly(acrylonitrile-co-vinylidene Chloride) Copolymer/Poly(n-tetradecyl acrylate-co-n-hexadecyl Acrylate) Sheath/Core Nanofiber-wrapped Thermo-regulated Filaments

Sai Chen, Lijuan Tao, Wenhua Cai, Haihui Liu et autres

Thermo-regulated fibers, which contain phase change materials with a melting temperature close to human body temperature, have attracted great scientific attention. Nanofibers with poly( n -tetradecyl acrylate- co - n -hexadecyl acrylate) (poly(TDA- co -HDA)) as the core material and poly(acrylonitrile- co …

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Genetic architectures of proximal and distal colorectal cancer are partly distinct.

Jeroen R. Huyghe, Tabitha A. Harrison, Stephanie A. Bien, Heather Hampel et autres

OBJECTIVE: An understanding of the etiologic heterogeneity of colorectal cancer (CRC) is critical for improving precision prevention, including individualized screening recommendations and the discovery of novel drug targets and repurposable drug candidates for chemoprevention. Known differences in molecular characteristics and environmental risk …

Essential Thrombocythaemia with Concomitant Waldenström Macroglobulinaemia: Case Report and Literature Review

Nina Lu, Chin Loon Neoh, Zhengying Ruan, Леи Жао et autres

Essential thrombocythaemia (ET) and Waldenström macroglobulinaemia (WM) are two distinct disorders. Studies have reported several cases of myeloproliferative neoplasms (MPNs) with concomitant plasma cell dyscrasia. However, there were no reported cases of ET with concomitant WM to date. Here, we present a …

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Erratum: Cyclin Dependent Kinase 1 (CDK1) Activates Cardiac Fibroblasts via Directly Phosphorylating Paxillin at Ser244

Sai Chen, Jian Zhao, Yu Zhu, Yun Zhu et autres

An error appeared in the article entitled "Cyclin Dependent Kinase 1 (CDK1) Activates Cardiac Fibroblasts via Directly Phosphorylating Paxillin at Ser244" by Chen Sai, Jiang Yunhan, Jian Zhao, Zhu Yu, Zhu Yun, Cao Zhezhe, Tang Fuqin, Xiao Yingbin, and Ma Ruiyan (Vol. …

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