Mingqian Lu

Real-world safety and effectiveness of fuzuloparib in patients with ovarian cancer: A prospective multicenter study

Bowen Huang, Jie Jiang, Mingqian Lu, Yingjie Yang et autres

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Abstract 2991: Superior detection of NTRK fusions across Chinese solid tumors using amplicon-based DNA and RNA NGS co-detection compared with hybrid-capture DNA-NGS

Mingqian Lu

Abstract Background: NTRK fusions are clinically actionable drivers across many solid tumors, with several tumor-agnostic targeted therapies approved. Traditional DNA-based assays often lack sensitivity for NTRK rearrangements. Although RNA-NGS improves fusion detection, the relative performance of amplicon-based DNA+RNA NGS co-detection versus hybrid-capture …

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[Retracted] Downregulation of Bmi‑1 is associated with suppressed tumorigenesis and induced apoptosis in CD44 + nasopharyngeal carcinoma cancer stem‑like cells

Xinhua Xu, Yang Liu, Jin Su, Daojun Li et autres

has decided that this paper should be retracted from the Journal on account of a lack of confidence in the presented data. The Editor apologizes to the readership for any inconvenience caused. [Oncology Reports 35: 923‑931, 2016; DOI: 10.3892/or.2015.4414].

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Multichannel deep learning prediction of major pathological response after neoadjuvant immunochemotherapy in lung cancer: a multicenter diagnostic study

Zuhan Geng, Kuo Li, Peiyuan Mei, Zhenyu Gong et autres

OBJECTIVES: This study aimed to develop a pretreatment CT-based multichannel predictor integrating deep learning features encoded by Transformer models for preoperative diagnosis of major pathological response (MPR) in non-small cell lung cancer (NSCLC) patients receiving neoadjuvant immunochemotherapy. MATERIAL AND METHODS: This multicenter …

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HRD status and genomic characteristics of Chinese NSCLC patients.

Mingqian Lu, Ning Gao

e20507 Background: Homologous recombination deficiency (HRD) is a condition marked by dysfunction in homologous recombination repair (HRR), leading to genomic instability and increased mutations. This study aims to clarify the HRD status and genomic characteristics of Chinese non-small cell lung cancer (NSCLC) …

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Safety and effectiveness of fuzuloparib in patients with ovarian cancer: A nationwide, multicenter, prospective real-world study.

Qinglei Gao, Jie Jiang, Mingqian Lu, Zhe Guo et autres

5572 Background: Fuzuloparib, a poly (ADP-ribose) polymerase (PARP) inhibitor, is approved in China for the treatment of platinum-sensitive recurrent (PSR) ovarian cancer (OC) and for maintenance therapy in newly diagnosed advanced and PSR OC. This study aims to evaluate the safety and …

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Clinical study of different interventional treatments for primary hepatocellular carcinoma based on propensity-score matching

Xiaobo Cheng, Li Yang, Mingqian Lu, Lei Wang et autres

BACKGROUND Transcatheter arterial chemoembolization (TACE) is the main treatment for patients with primary hepatocellular carcinoma (PHC) who miss the opportunity to undergo surgery. Conventional TACE (c-TACE) uses iodized oil as an embolic agent, which is easily washed by blood and affects its …

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[Analysis of gut target microbiota and species difference in patients with obstructive sleep apnea based on 16S rRNA sequencing].

Juan Zhu, Mingqian Lu, Yeying Sun, Li Liu et autres

OBJECTIVE: To explore the difference in gut microbiota composition between patients with obstructive sleep apnea (OSA) and healthy individuals and the role of gut microbiota in the pathogenesis of OSA. METHODS: Thirty-nine patients with OSA admitted to our hospital between May and …

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401TiP Oral opioid vs intravenous patient-controlled analgesia (PCA) with hydromorphone bolus-only or continuous infusion to maintain analgesia for severe cancer pain: A randomized phase III trial

Rongbo Lin, Li He, Mingqian Lu, Yuan Wang et autres

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Reinforcement Learning Swarm of Self-Organizing Unmanned Surface Vehicles with Unavailable Dynamics

Ning Wang, Yong‐Jin Liu, Mingqian Lu

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Intravenous Patient-Controlled Analgesia Versus Oral Opioid to Maintain Analgesia for Severe Cancer Pain: A Randomized Phase II Trial

Rongbo Lin, Jinfeng Zhu, Y. Luo, Xia Lv et autres

BACKGROUND: Optimal analgesic maintenance for severe cancer pain is unknown. This study evaluated the efficacy and safety of intravenous patient-controlled analgesia (IPCA) with continuous infusion plus rescue dose or bolus-only dose versus conventional oral extended-release morphine as a background dose with normal-release …

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Identification of potential genes correlated with breast cancer metastasis and prognosis

Chao Tan, Fang Zuo, Mingqian Lu, Sai Chen et autres

We aimed to screen, via bioinformatics analyses, potential gene markers related to BC metastasis and prognosis. A gene expression dataset (GSE102818) and relevant clinical information were downloaded from the GEO database and TCGA, respectively. Then, differentially expressed genes (DEGs) were identified between …

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