Guanghong Xu

Temporary Spinal Cord Stimulation versus Dorsal Root Ganglion Pulsed Radiofrequency for Preventing Postherpetic Neuralgia: A Propensity-Score–Matched Real-World Study

Penghui Ke, Likui Wang, Yang Song, Wenfeng Xu et autres

cn (code pays fourni par la source)

Dezocine-mediated reversal of sufentanil-induced respiratory depression and its mitigation of adverse reactions: A clinical investigation

Yong-Kang Gui, Li-fang Liu, Meng-lei Shan, Jia-wei Wang et autres

cn (code pays fourni par la source)

LncRNA SNHG5 promotes macrophage lipid accumulation and aggravates atherosclerosis by targeting the miR-216a-5p/HDAC3/ABCA1 axis

Xian Liu, Hui-Hui Wang, Xin-Yu Lan, Shao-Yang Sun et autres

cn (code pays fourni par la source)

Development of a machine learning-based prediction model for postoperative delirium in frail elderly patients undergoing noncardiac surgery under general anesthesia

Qiufeng Wang, Dali Mu, Xiaofeng Wang, Jianpeng Wang et autres

cn (code pays fourni par la source)

Development of a Machine Learning-Based Prediction Model for Postoperative Delirium in Frail Elderly Patients Undergoing Non-Cardiac Surgery Under General Anesthesia

Qiufeng Wang, Dali Mu, X M Wang, Jianpeng Wang et autres

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Standardization of nasal airway structure model of Chinese Han nationality for characterization of nasal formulation spatial deposition atlases

Zeru Li, Huipeng Xu, Siwen Wang, Qin Nie et autres

The deposition characteristics of nasal formulations directly determine the efficacy of the drugs, whilst the complexity of human nasal airway structure encumbers quantitative evaluation of nasal spatial deposition. Male and female standard nasal airway structure models were calculated from computed tomography data …

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LncRNA MIR17HG accelerates the development of atherosclerosis by promoting macrophage pyroptosis through the miR-301a-3p/TXNIP pathway

Yu‐Ping Wang, Xian Liu, Xiaodan Xu, Lei Hui et autres

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Polycomponent metal-organic frameworks of substituent polydispersion hydroxypropyl-β-cyclodextrin as inhalable drug carrier

Xiaojian He, Huipeng Xu, Xiangyu Zhao, Feng Li et autres

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Opioid-Free Anesthesia with Esketamine Combined with Iliac Fascia Block in Elderly Patients Undergoing Hip Surgery

Rui Xiao, Jinpeng Zhang, Wen-Feng Xi, Guanghong Xu et autres

Background: Most patients with hip fractures are elderly people with relatively high risks of cardiovascular and cerebrovascular accidents. Esketamine has little effect on haemodynamics and has an exact analgesic effect, which is beneficial for patients with intolerance to surgery and anaesthesia. Therefore, …

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Intraoperative Dexmedetomidine Infusion Improved Postoperative Sleep Quality and Melatonin Secretion in Patients Undergoing Elective Thoracoscopic Lung Surgery: A Prospective, Randomized Study

Bin Mei, Yueyue Yang, Juntao Weng, Rui Yang et autres

Background: Dexmedetomidine has been reported to improve postoperative sleep quality. However, the underlying mechanism remains unclear. This study aimed to investigate the effect of intraoperative dexmedetomidine infusion on postoperative sleep quality and changes in melatonin secretion in older patients undergoing elective thoracoscopic …

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Anesthesia/surgery leads to blood-brain barrier disruption via the transcellular and paracellular pathways, and postoperative delirium-like behavior: A comparative study in mice of different ages

Xudong Hu, Lixia Liu, Xin Da, Si-hui Zhu et autres

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Anesthesia/surgery activate MMP9 leading to blood-brain barrier disruption, triggering neuroinflammation and POD-like behavior in aged mice

Yun Hang Hu, Xudong Hu, Ziqing He, Yang Liu et autres

• MMP9 injures tight junctions and pericytes , leading to BBB disruption and POD-like behavior . MMP9 inhibitors can impedes this process, attenuating POD-like behaviors. • MMP9 also promotes endothelial transcytosis , which further leads to BBB disruption. MMP9 inhibitors can reverse …

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