Accès ouvert
2026
article
OpenAlex
Antonio Del Casale, Paolo Girardi, Jan Francesco Arena, Claudio Cantelmi et autres
Advances in psychiatric genetics have substantially reshaped current models of schizophrenia-spectrum disorders, shifting the focus from single risk factors to polygenic liability and its interaction with environmental adversity. Polygenic risk scores (PRS) provide a quantitative index of genetic vulnerability; however, how this …
it
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Accès ouvert
2025
article
OpenAlex
Edoardo Monaco, Paolo Girardi, P. Falaschi, Stefano Ferracuti et autres
Bullying is a manifestation of occupational stress and can therefore be considered as a real organizational pathology. Include the activities of the surgery dedicated to Mobbing, Unit of Occupational Medicine Sant' Andrea Hospital, which began operations in June 2001. In over ten …
it
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Accès ouvert
2024
editorial
OpenAlex
Antonio Del Casale, Jan Francesco Arena, Paolo Girardi, Gloria Angeletti
Ten years ago, the Society for Women’s Health Research highlighted sleep as a significant area of interest in women’s health research [...]
it
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Accès ouvert
2024
review
OpenAlex
Antonio Del Casale, Jan Francesco Arena, Francesca Giannetti, Antonino Minervino et autres
INTRODUCTION: Melatonin, a hormone produced by the pineal gland, regulates the sleep-wake cycle and is effective in restoring biological rhythms. Prolonged-release melatonin (PRM) is designed to mimic the natural physiological pattern of melatonin release. In circadian medicine, PRM can be used to …
it
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Accès ouvert
2023
article
OpenAlex
Antonio Del Casale, Maurizio Simmaco, Martina Nicole Modesti, Clarissa Zocchi et autres
Background: The objective of this study was to investigate the DRD2 rs1800497, rs1799732, rs1801028, DRD3 rs6280, and HTR2A rs6314, rs7997012, and rs6311 single-nucleotide polymorphism (SNP) correlations with resistance to second-generation antipsychotics (SGAs) in a real-world sample of patients with treatment-resistant mental disorders. …
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Accès ouvert
2023
article
OpenAlex
Paolo Girardi, Martina Nicole Modesti, Antonio Del Casale
In 2020, the number of international migrants worldwide—people residing in a country other than their country of birth—reached almost 281 million [...]
it
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Accès ouvert
2022
editorial
OpenAlex
Paolo Girardi, Martina Nicole Modesti, Antonio Del Casale
Is war evitable? Besides being a question to which humanity is struggling to answer, it is the title of the letter exchange between Freud and Einstein that inspired this editorial. The aim is to address this question and analyse whether there is …
it
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Accès ouvert
2022
article
OpenAlex
Antonio Del Casale, Marco Paolini, Giovanna Gentile, Marina Borro et autres
Patients affected by mental disorders smoke more than the general population. The reasons behind this habit are genetic, environmental, etc. This study aims to investigate the correlations between some polymorphisms and the smoking habits and nicotine dependence in patients with psychiatric disorders. …
it
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Accès ouvert
2022
article
OpenAlex
Antonio Del Casale, Leda Marina Pomes, Luca Bonanni, Federica Fiaschè et autres
Treatment-resistant depression (TRD) reduces affected patients’ quality of life and leads to important social health care costs. Pharmacogenomics-guided treatment (PGT) may be effective in the cure of TRD. The main aim of this study was to evaluate the clinical changes after PGT …
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Accès ouvert
2021
article
OpenAlex
Giulia Maria Giordano, Andrea Perrottelli, Armida Mucci, Giorgio Di Lorenzo et autres
Neurocognitive deficits and negative symptoms (NS) have a pivotal role in subjects with schizophrenia (SCZ) due to their impact on patients' functioning in everyday life and their influence on goal-directed behavior and decision-making. P3b is considered an optimal electrophysiological candidate biomarker of …
it
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Accès ouvert
2021
article
OpenAlex
Antonio Del Casale, Clarissa Zocchi, Georgios Demetrios Kotzalidis, Federica Fiaschè et autres
Major depressive disorder (MDD) and other affective disorders may surreptitiously arise in children and adolescents during their school period and impair their social and educational functioning. Besides the social and personal burden, which are increased during the SARS-CoV-2 pandemic, the onset of …
it
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Accès ouvert
2021
article
OpenAlex
Laura Palagini, Raffaele Manni, Eugenio Aguglia, Mario Amore et autres
Introduction: Insomnia and circadian rhythm disorders, such as the delayed sleep phase syndrome, are frequent in psychiatric disorders and their evaluation and management in early stages should be a priority. The aim of this paper was to express recommendations on the use …
it, fr
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