Accès ouvert
2026
article
OpenAlex
Antonio Del Casale, Paolo Girardi, Jan Francesco Arena, Claudio Cantelmi et autres
Advances in psychiatric genetics have substantially reshaped current models of schizophrenia-spectrum disorders, shifting the focus from single risk factors to polygenic liability and its interaction with environmental adversity. Polygenic risk scores (PRS) provide a quantitative index of genetic vulnerability; however, how this …
it
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Accès ouvert
2023
article
OpenAlex
Valeria Raparelli, Giulio Francesco Romiti, Giulia Di Teodoro, Ruggiero Seccia et autres
BACKGROUND: Mechanisms of myocardial ischemia in obstructive and non-obstructive coronary artery disease (CAD), and the interplay between clinical, functional, biological and psycho-social features, are still far to be fully elucidated. OBJECTIVES: To develop a machine-learning (ML) model for the supervised prediction of …
ca, it, gb
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Accès ouvert
2022
article
OpenAlex
Valeria Raparelli, Cristina Nocella, Marco Proietti, Giulio Francesco Romiti et autres
Abstract Background Data on the interplay between sexual hormones balance, platelet function and clinical outcomes of adults with ischemic heart disease (IHD) are still lacking. Objective To assess the association between the Testosterone (T)-to-Estradiol (E2) Ratio (T/E2) and platelet activation biomarkers in …
ca, it, gb
(code pays fourni par la source)